Journal article 121 views
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
Jürgen Brem 
,
Tharindi Panduwawala ,
Jon Ulf Hansen,
Joanne Hewitt,
Edgars Liepins,
Pawel Donets ,
Laura Espina,
Alistair J. M. Farley,
Kirill Shubin,
Gonzalo Gomez Campillos ,
Paula Kiuru ,
Shifali Shishodia ,
Daniel Krahn,
Robert K. Leśniak,
Juliane Schmidt,
Karina Calvopiña,
María-Carmen Turrientes,
Madeline E. Kavanagh ,
Dmitrijs Lubriks ,
Philip Hinchliffe,
Gareth W. Langley ,
Ali F. Aboklaish,
Anders Eneroth,
Maria Backlund ,
Andrei G. Baran,
Elisabet I. Nielsen ,
Michael Speake,
Janis Kuka,
John Robinson,
Solveiga Grinberga,
Lindsay Robinson,
Michael A. McDonough ,
Anna M. Rydzik,
Thomas M. Leissing,
Juan Carlos Jimenez-Castellanos,
Matthew B. Avison,
Solange Da Silva Pinto,
Andrew D. Pannifer,
Marina Martjuga,
Emma Widlake ,
Martins Priede ,
Iva Hopkins Navratilova,
Marek Gniadkowski,
Anna Karin Belfrage ,
Peter Brandt ,
Jari Yli-Kauhaluoma ,
Eric Bacque,
Malcolm G. P. Page ,
Fredrik Björkling ,
Jon Tyrrell ,
James Spencer ,
Pauline A. Lang ,
Pawel Baranczewski ,
Rafael Cantón ,
Stuart P. McElroy,
Philip S. Jones,
Fernando Baquero,
Edgars Suna ,
Angus Morrison,
Timothy R. Walsh,
Christopher J. Schofield
,
Tharindi Panduwawala ,
Jon Ulf Hansen,
Joanne Hewitt,
Edgars Liepins,
Pawel Donets ,
Laura Espina,
Alistair J. M. Farley,
Kirill Shubin,
Gonzalo Gomez Campillos ,
Paula Kiuru ,
Shifali Shishodia ,
Daniel Krahn,
Robert K. Leśniak,
Juliane Schmidt,
Karina Calvopiña,
María-Carmen Turrientes,
Madeline E. Kavanagh ,
Dmitrijs Lubriks ,
Philip Hinchliffe,
Gareth W. Langley ,
Ali F. Aboklaish,
Anders Eneroth,
Maria Backlund ,
Andrei G. Baran,
Elisabet I. Nielsen ,
Michael Speake,
Janis Kuka,
John Robinson,
Solveiga Grinberga,
Lindsay Robinson,
Michael A. McDonough ,
Anna M. Rydzik,
Thomas M. Leissing,
Juan Carlos Jimenez-Castellanos,
Matthew B. Avison,
Solange Da Silva Pinto,
Andrew D. Pannifer,
Marina Martjuga,
Emma Widlake ,
Martins Priede ,
Iva Hopkins Navratilova,
Marek Gniadkowski,
Anna Karin Belfrage ,
Peter Brandt ,
Jari Yli-Kauhaluoma ,
Eric Bacque,
Malcolm G. P. Page ,
Fredrik Björkling ,
Jon Tyrrell ,
James Spencer ,
Pauline A. Lang ,
Pawel Baranczewski ,
Rafael Cantón ,
Stuart P. McElroy,
Philip S. Jones,
Fernando Baquero,
Edgars Suna ,
Angus Morrison,
Timothy R. Walsh,
Christopher J. Schofield
Nature Chemistry, Volume: 14, Issue: 1, Pages: 15 - 24
Swansea University Author:
Jon Tyrrell
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1038/s41557-021-00831-x
Abstract
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
| Published in: | Nature Chemistry |
|---|---|
| ISSN: | 1755-4330 1755-4349 |
| Published: |
Springer Science and Business Media LLC
2022
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa70430 |
| College: |
Faculty of Medicine, Health and Life Sciences |
|---|---|
| Funders: |
The ENABLE project is financially supported by contributions from Academic and SME partners. The Oxford work was also supported by Cancer Research UK (C9047/A24759), the Medical Research Council, the Biotechnology and Biological Research Council (BB/S50676X/1) and the Ineos Oxford Institute for Antimicrobial Research (C.J.S.). This research was funded in whole, or in part, by the Wellcome Trust (grant no. 106244/Z/14/Z and no. 099141/Z/12/Z). The Bristol work was also supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) grant R01AI100560 (J.S. and P.H.) (the content is the responsibility of the authors and does not necessarily represent official views of the NIH) and the BrisSynBio Biosuite (UK Biotechnology and Biological Sciences (BBSRC) and Engineering and Physical Sciences (EPSRC) Research Councils (BB/L01386X/1) and BBSRC ALERT14 initiative (BB/M012107/1). |
| Issue: |
1 |
| Start Page: |
15 |
| End Page: |
24 |