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Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

Samuel T. Cahill, Jon Tyrrell Orcid Logo, Iva Hopkins Navratilova, Karina Calvopiña, Sean W. Robinson, Christopher T. Lohans, Michael A. McDonough, Ricky Cain, Colin W.G. Fishwick, Matthew B. Avison, Timothy R. Walsh, Christopher J. Schofield, Jürgen Brem

Biochimica et Biophysica Acta (BBA) - General Subjects, Volume: 1863, Issue: 4, Pages: 742 - 748

Swansea University Author: Jon Tyrrell Orcid Logo

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Published in: Biochimica et Biophysica Acta (BBA) - General Subjects
ISSN: 0304-4165
Published: Elsevier BV 2019
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa70436
Item Description: Author Accepted Manuscript available at https://discovery.dundee.ac.uk/en/publications/studies-on-the-inhibition-of-ampc-and-other-%CE%B2-lactamases-by-cycli
Keywords: β-lactam antibiotic resistance; Cyclic boronate inhibitors; Metallo and serine β-lactamase inhibition; Transition state analogueβ-lactamase induction; Antimicrobial clinical coverage
College: Faculty of Medicine, Health and Life Sciences
Funders: We thank the Medical Research Council, the SWON alliance (MR/N002679/1), the SAMRC-Newton grant, the Wellcome Trust, and the European Gram-Negative Antibacterial Engine (ENABLE) for funding our MBL work.
Issue: 4
Start Page: 742
End Page: 748