Journal article 986 views
Stroboscopic fluorescence lifetime imaging
Mark D Holton,
Oscar R Silvestre,
Rachel J Errington,
Paul J Smith,
Daniel R Matthews,
Paul Rees 
,
Huw Summers
,
Huw Summers
Optics Express, Volume: 17, Issue: 7, Pages: 5205 - 5216
Swansea University Authors:
Paul Rees , Huw Summers
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1364/OE.17.005205
Abstract
Stroboscopic fluorescence lifetime imaging
| Published in: | Optics Express |
|---|---|
| ISSN: | 1094-4087 |
| Published: |
2009
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa6048 |
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| Item Description: |
This paper presents the first demonstration of a wholly novel experimental technique for time resolved fluorescence imaging. There are two established approaches to temporal resolution, i. direct observation in time domain using fast detectors or ii. indirect observation from frequency response measurements. This paper presents an approach based on modulated pulsed excitation (stroboscopic) and d.c. detection. It transforms the measurement of fluorescence lifetime in that it uses time integrated detection thus avoiding the usual trade-off between high speed resolution and low detection signal. The work was funded by EPSRC grant, EP/E013104/1 |
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| College: |
Faculty of Science and Engineering |
| Issue: |
7 |
| Start Page: |
5205 |
| End Page: |
5216 |