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2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition

Romeo Romagnoli, Maria Kimatrai Salvador, Santiago Schiaffino Ortega, Pier Giovanni Baraldi, Paola Oliva, Stefania Baraldi, Luisa Carlota Lopez-Cara, Andrea Brancale, Salvatore Ferla Orcid Logo, Ernest Hamel, Jan Balzarini, Sandra Liekens, Elena Mattiuzzo, Giuseppe Basso, Giampietro Viola

European Journal of Medicinal Chemistry, Volume: 143, Pages: 683 - 698

Swansea University Author: Salvatore Ferla Orcid Logo

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DOI (Published version): 10.1016/j.ejmech.2017.11.096

Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2018
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URI: https://cronfa.swan.ac.uk/Record/cronfa55477
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first_indexed 2020-10-23T08:04:24Z
last_indexed 2020-12-11T04:19:45Z
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spelling 2020-12-10T14:45:04.3393926 v2 55477 2020-10-22 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition d4c62248f510e3b221916989a7bbe6a6 0000-0002-5918-9237 Salvatore Ferla Salvatore Ferla true false 2020-10-22 PHAR Journal Article European Journal of Medicinal Chemistry 143 683 698 Elsevier BV 0223-5234 Microtubule; Tubulin polymerization inhibitors; Antiproliferative agents; Colchicine site; Structure-activity relationship 1 1 2018 2018-01-01 10.1016/j.ejmech.2017.11.096 http://orca.cf.ac.uk/107819/ COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2020-12-10T14:45:04.3393926 2020-10-22T09:12:31.2865105 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Romeo Romagnoli 1 Maria Kimatrai Salvador 2 Santiago Schiaffino Ortega 3 Pier Giovanni Baraldi 4 Paola Oliva 5 Stefania Baraldi 6 Luisa Carlota Lopez-Cara 7 Andrea Brancale 8 Salvatore Ferla 0000-0002-5918-9237 9 Ernest Hamel 10 Jan Balzarini 11 Sandra Liekens 12 Elena Mattiuzzo 13 Giuseppe Basso 14 Giampietro Viola 15
title 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
spellingShingle 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
Salvatore Ferla
title_short 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
title_full 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
title_fullStr 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
title_full_unstemmed 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
title_sort 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
author_id_str_mv d4c62248f510e3b221916989a7bbe6a6
author_id_fullname_str_mv d4c62248f510e3b221916989a7bbe6a6_***_Salvatore Ferla
author Salvatore Ferla
author2 Romeo Romagnoli
Maria Kimatrai Salvador
Santiago Schiaffino Ortega
Pier Giovanni Baraldi
Paola Oliva
Stefania Baraldi
Luisa Carlota Lopez-Cara
Andrea Brancale
Salvatore Ferla
Ernest Hamel
Jan Balzarini
Sandra Liekens
Elena Mattiuzzo
Giuseppe Basso
Giampietro Viola
format Journal article
container_title European Journal of Medicinal Chemistry
container_volume 143
container_start_page 683
publishDate 2018
institution Swansea University
issn 0223-5234
doi_str_mv 10.1016/j.ejmech.2017.11.096
publisher Elsevier BV
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
url http://orca.cf.ac.uk/107819/
document_store_str 0
active_str 0
published_date 2018-01-01T04:09:42Z
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score 11.037603

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