Journal article 738 views
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
Romeo Romagnoli,
Paola Oliva,
Maria Kimatrai Salvador,
Maria Encarnacion Camacho,
Chiara Padroni,
Andrea Brancale,
Salvatore Ferla ,
Ernest Hamel,
Roberto Ronca,
Elisabetta Grillo,
Roberta Bortolozzi,
Fatlum Rruga,
Elena Mariotto,
Giampietro Viola
European Journal of Medicinal Chemistry, Volume: 181, Start page: 111577
Swansea University Author: Salvatore Ferla
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1016/j.ejmech.2019.111577
Abstract
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
Published in: | European Journal of Medicinal Chemistry |
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ISSN: | 0223-5234 |
Published: |
Elsevier BV
2019
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Online Access: |
Check full text
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URI: | https://cronfa.swan.ac.uk/Record/cronfa55235 |
Keywords: |
Microtubules; Structure-activity relationship; 1H-pyrazole; Antiproliferative activity; Tubulin |
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College: |
Faculty of Medicine, Health and Life Sciences |
Start Page: |
111577 |