Journal article 864 views
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
Paola Oliva,
Romeo Romagnoli,
Stefano Manfredini,
Andrea Brancale,
Salvatore Ferla ,
Ernest Hamel,
Roberto Ronca,
Federica Maccarinelli,
Arianna Giacomini,
Fatlum Rruga,
Elena Mariotto,
Giampietro Viola,
Roberta Bortolozzi
European Journal of Medicinal Chemistry, Volume: 200, Start page: 112448
Swansea University Author: Salvatore Ferla
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DOI (Published version): 10.1016/j.ejmech.2020.112448
Abstract
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
Published in: | European Journal of Medicinal Chemistry |
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ISSN: | 0223-5234 |
Published: |
Elsevier BV
2020
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Online Access: |
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URI: | https://cronfa.swan.ac.uk/Record/cronfa55226 |
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Keywords: |
Microtubules; Benzo[b]furan; In vivo activity; Inhibition tubulin assembly; Colchicine binding site |
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College: |
Faculty of Medicine, Health and Life Sciences |
Start Page: |
112448 |