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Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
Romeo Romagnoli,
Filippo Prencipe,
Paola Oliva,
Maria Kimatrai Salvador,
Andrea Brancale,
Salvatore Ferla ,
Ernest Hamel,
Giampietro Viola,
Roberta Bortolozzi,
Leentje Persoons,
Jan Balzarini,
Sandra Liekens,
Dominique Schols
Bioorganic Chemistry, Volume: 97, Start page: 103665
Swansea University Author: Salvatore Ferla
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DOI (Published version): 10.1016/j.bioorg.2020.103665
Abstract
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
Published in: | Bioorganic Chemistry |
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ISSN: | 0045-2068 |
Published: |
Elsevier BV
2020
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URI: | https://cronfa.swan.ac.uk/Record/cronfa54944 |
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2020-09-03T12:34:35.9246645 v2 54944 2020-08-11 Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization d4c62248f510e3b221916989a7bbe6a6 0000-0002-5918-9237 Salvatore Ferla Salvatore Ferla true false 2020-08-11 PHAR Journal Article Bioorganic Chemistry 97 103665 Elsevier BV 0045-2068 Microtubules; Structure-activity relationship; Indole; Antiproliferative activity; Tubulin 1 4 2020 2020-04-01 10.1016/j.bioorg.2020.103665 COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2020-09-03T12:34:35.9246645 2020-08-11T20:35:39.4387459 Romeo Romagnoli 1 Filippo Prencipe 2 Paola Oliva 3 Maria Kimatrai Salvador 4 Andrea Brancale 5 Salvatore Ferla 0000-0002-5918-9237 6 Ernest Hamel 7 Giampietro Viola 8 Roberta Bortolozzi 9 Leentje Persoons 10 Jan Balzarini 11 Sandra Liekens 12 Dominique Schols 13 |
title |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
spellingShingle |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization Salvatore Ferla |
title_short |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
title_full |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
title_fullStr |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
title_full_unstemmed |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
title_sort |
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization |
author_id_str_mv |
d4c62248f510e3b221916989a7bbe6a6 |
author_id_fullname_str_mv |
d4c62248f510e3b221916989a7bbe6a6_***_Salvatore Ferla |
author |
Salvatore Ferla |
author2 |
Romeo Romagnoli Filippo Prencipe Paola Oliva Maria Kimatrai Salvador Andrea Brancale Salvatore Ferla Ernest Hamel Giampietro Viola Roberta Bortolozzi Leentje Persoons Jan Balzarini Sandra Liekens Dominique Schols |
format |
Journal article |
container_title |
Bioorganic Chemistry |
container_volume |
97 |
container_start_page |
103665 |
publishDate |
2020 |
institution |
Swansea University |
issn |
0045-2068 |
doi_str_mv |
10.1016/j.bioorg.2020.103665 |
publisher |
Elsevier BV |
document_store_str |
0 |
active_str |
0 |
published_date |
2020-04-01T04:08:48Z |
_version_ |
1763753621048000512 |
score |
11.037603 |