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Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing

Tom Pritchard, Michael Darcy, Jack Davies, Elysia Geeves, Louis Giron, Sahar Sattar, Carol Ling, David O'connor, Raoul van Loon Orcid Logo, Hari Arora Orcid Logo

Strain, Volume: 61, Issue: 3

Swansea University Authors: Tom Pritchard, Michael Darcy, Jack Davies, Elysia Geeves, Louis Giron, Sahar Sattar, Carol Ling, Raoul van Loon Orcid Logo, Hari Arora Orcid Logo

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DOI (Published version): 10.1111/str.70010

Abstract

In the United Kingdom, aortic valve stenosis is a common heart condition and the cause of morbidity within the elderly population. A common treatment for aortic valve stenosis is replacement with a prosthetic valve, either mechanical or bioprosthetic, each with its own advantages and limitations. He...

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Published in: Strain
ISSN: 0039-2103 1475-1305
Published: Wiley 2025
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URI: https://cronfa.swan.ac.uk/Record/cronfa69547
first_indexed 2025-05-21T08:18:26Z
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A common treatment for aortic valve stenosis is replacement with a prosthetic valve, either mechanical or bioprosthetic, each with its own advantages and limitations. Here, the aim is to introduce a workflow for the creation and testing of phantom or prosthetic aortic heart valves to verify computational models and test the effect of valve design parameters on strain profile within the valve leaflet. Three silicone valve geometries were created and inserted into a physiologically representative flow system. High-speed digital image correlation was used to measure displacement and calculate principal strain in a single leaflet. The leaflet free edge was tracked during coaptation while the transvalvular pressure was recorded. A two stage closing process was established, the primary stage demonstrating geometry and material dependency, and secondary exhibiting solely material dependency. Areas of high principal strain were identified below the coaptation area with peaks near the commissures. 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spelling 2025-06-11T13:53:10.0751151 v2 69547 2025-05-21 Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing ca3aa35fb1034cdbeb740f8fbead4817 Tom Pritchard Tom Pritchard true false b5aec8101b64f8f9a02f142c2bc91cd6 Michael Darcy Michael Darcy true false b9ac7cfce4609c61c2b78f1e2dafa237 Jack Davies Jack Davies true false 06d7aefdae71315057d568a150731620 Elysia Geeves Elysia Geeves true false 2afc5b9fe0b2fa3fa003d98ced699f0d Louis Giron Louis Giron true false dc80b43f527ae93927f0316028d3cea3 Sahar Sattar Sahar Sattar true false ebf4f5b9ebf6a3ab4ff494a8e5d9812a Carol Ling Carol Ling true false 880b30f90841a022f1e5bac32fb12193 0000-0003-3581-5827 Raoul van Loon Raoul van Loon true false ed7371c768e9746008a6807f9f7a1555 0000-0002-9790-0907 Hari Arora Hari Arora true false 2025-05-21 In the United Kingdom, aortic valve stenosis is a common heart condition and the cause of morbidity within the elderly population. A common treatment for aortic valve stenosis is replacement with a prosthetic valve, either mechanical or bioprosthetic, each with its own advantages and limitations. Here, the aim is to introduce a workflow for the creation and testing of phantom or prosthetic aortic heart valves to verify computational models and test the effect of valve design parameters on strain profile within the valve leaflet. Three silicone valve geometries were created and inserted into a physiologically representative flow system. High-speed digital image correlation was used to measure displacement and calculate principal strain in a single leaflet. The leaflet free edge was tracked during coaptation while the transvalvular pressure was recorded. A two stage closing process was established, the primary stage demonstrating geometry and material dependency, and secondary exhibiting solely material dependency. Areas of high principal strain were identified below the coaptation area with peaks near the commissures. This work highlights the importance of further research into the effect of valve parameters on the strain profile within the leaflets to minimise failure risk in new replacement heart valve designs. Journal Article Strain 61 3 Wiley 0039-2103 1475-1305 aortic heart valve; aortic stenosis; diastole; digital image correlation; phantom 10 6 2025 2025-06-10 10.1111/str.70010 COLLEGE NANME COLLEGE CODE Swansea University SU Library paid the OA fee (TA Institutional Deal) European Regional Development Fund through the Welsh Government and Swansea University (SU), SU Research Excellence Scholarship, UKRI DTP and SU Employability Fund 2025-06-11T13:53:10.0751151 2025-05-21T09:13:15.7486837 Faculty of Science and Engineering School of Engineering and Applied Sciences - Biomedical Engineering Tom Pritchard 1 Michael Darcy 2 Jack Davies 3 Elysia Geeves 4 Louis Giron 5 Sahar Sattar 6 Carol Ling 7 David O'connor 8 Raoul van Loon 0000-0003-3581-5827 9 Hari Arora 0000-0002-9790-0907 10 69547__34461__6ee5cd6ec6c5475aa6e4899bbee361b4.pdf 69547.pdf 2025-06-11T13:50:44.8850085 Output 11029976 application/pdf Version of Record true © 2025 The Author(s). This is an open access article under the terms of the Creative Commons Attribution License. true eng http://creativecommons.org/licenses/by/4.0/
title Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
spellingShingle Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
Tom Pritchard
Michael Darcy
Jack Davies
Elysia Geeves
Louis Giron
Sahar Sattar
Carol Ling
Raoul van Loon
Hari Arora
title_short Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
title_full Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
title_fullStr Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
title_full_unstemmed Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
title_sort Effect of Aortic Valve Geometry on Leaflet Strain Within a Phantom Silicone Aortic Heart Valve During Closing
author_id_str_mv ca3aa35fb1034cdbeb740f8fbead4817
b5aec8101b64f8f9a02f142c2bc91cd6
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author_id_fullname_str_mv ca3aa35fb1034cdbeb740f8fbead4817_***_Tom Pritchard
b5aec8101b64f8f9a02f142c2bc91cd6_***_Michael Darcy
b9ac7cfce4609c61c2b78f1e2dafa237_***_Jack Davies
06d7aefdae71315057d568a150731620_***_Elysia Geeves
2afc5b9fe0b2fa3fa003d98ced699f0d_***_Louis Giron
dc80b43f527ae93927f0316028d3cea3_***_Sahar Sattar
ebf4f5b9ebf6a3ab4ff494a8e5d9812a_***_Carol Ling
880b30f90841a022f1e5bac32fb12193_***_Raoul van Loon
ed7371c768e9746008a6807f9f7a1555_***_Hari Arora
author Tom Pritchard
Michael Darcy
Jack Davies
Elysia Geeves
Louis Giron
Sahar Sattar
Carol Ling
Raoul van Loon
Hari Arora
author2 Tom Pritchard
Michael Darcy
Jack Davies
Elysia Geeves
Louis Giron
Sahar Sattar
Carol Ling
David O'connor
Raoul van Loon
Hari Arora
format Journal article
container_title Strain
container_volume 61
container_issue 3
publishDate 2025
institution Swansea University
issn 0039-2103
1475-1305
doi_str_mv 10.1111/str.70010
publisher Wiley
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Biomedical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Biomedical Engineering
document_store_str 1
active_str 0
description In the United Kingdom, aortic valve stenosis is a common heart condition and the cause of morbidity within the elderly population. A common treatment for aortic valve stenosis is replacement with a prosthetic valve, either mechanical or bioprosthetic, each with its own advantages and limitations. Here, the aim is to introduce a workflow for the creation and testing of phantom or prosthetic aortic heart valves to verify computational models and test the effect of valve design parameters on strain profile within the valve leaflet. Three silicone valve geometries were created and inserted into a physiologically representative flow system. High-speed digital image correlation was used to measure displacement and calculate principal strain in a single leaflet. The leaflet free edge was tracked during coaptation while the transvalvular pressure was recorded. A two stage closing process was established, the primary stage demonstrating geometry and material dependency, and secondary exhibiting solely material dependency. Areas of high principal strain were identified below the coaptation area with peaks near the commissures. This work highlights the importance of further research into the effect of valve parameters on the strain profile within the leaflets to minimise failure risk in new replacement heart valve designs.
published_date 2025-06-10T05:28:28Z
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score 11.089386

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