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COVID-19 and influenza vaccine uptake among pregnant women in national cohorts of England and Wales

Xinchun Gu Orcid Logo, Utkarsh Agrawal, Will Midgley Orcid Logo, Stuart Bedston, Sneha N. Anand, Rosalind Goudie, Rachel Byford, Mark Joy, Gavin Jamie Orcid Logo, Uy Hoang, Jose M. Ordóñez-Mena, Chris Robertson Orcid Logo, F. D. Richard Hobbs, Ashley Akbari Orcid Logo, Aziz Sheikh Orcid Logo, Simon de Lusignan Orcid Logo

npj Vaccines, Volume: 9, Issue: 1

Swansea University Authors: Will Midgley Orcid Logo, Stuart Bedston, Ashley Akbari Orcid Logo

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DOI (Published version): 10.1038/s41541-024-00934-9

Abstract

Vaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities in pregnant women during the COVID-19 pandemic to inform v...

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Published in: npj Vaccines
ISSN: 2059-0105
Published: Springer Science and Business Media LLC 2024
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URI: https://cronfa.swan.ac.uk/Record/cronfa67408
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Abstract: Vaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities in pregnant women during the COVID-19 pandemic to inform vaccination interventions. We used data from the Oxford-Royal College of General Practitioners Research and Surveillance Centre database in England and the Secure Anonymised Information Linkage Databank in Wales. The uptake of at least one dose of vaccine was 40.2% for COVID-19 and 41.8% for influenza among eligible pregnant women. We observed disparities in COVID-19 and influenza vaccine uptake, with socioeconomically deprived and ethnic minority groups showing lower vaccination rates. The suboptimal uptake of COVID-19 and influenza vaccines, especially in those from socioeconomically deprived backgrounds and Black, mixed or other ethnic groups, underscores the necessity for interventions to reduce vaccine hesitancy and enhance acceptance in pregnant women.
College: Faculty of Medicine, Health and Life Sciences
Funders: ThisresearchispartoftheDataandConnectivityNationalCoreStudy,ledby HealthDataResearchUKinpartnershipwiththeOfficeforNationalStatistics and funded by UK Research and Innovation (grant ref MC_PC_20058).This work was also supported by The Alan Turing Institute via ‘Towards Turing 2.0’ EPSRC Grant Funding. This work was supported by the Con-COV team funded by the Medical Research Council (grant number: MR/V028367/1). This work was supported by Health Data Research UK, which receives its funding from HDRUKLtd (HDR 9006), funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), and the Wellcome Trust. Data and Connectivity: COVID-19 Vaccines Pharmacovigilance National Core Study— Uptake, safety and effectiveness of COVID-19 vaccines in pregnancy; children and young people; those receiving booster doses; and disease caused by different variants (2021.0158) is a partnership between the University of Edinburgh, University of Oxford, University of Strathclyde, Queen’s University Belfast, Swansea University, Imperial College London and the Office for National Statistics. Additionally, the authors acknowledge the support of BREATHE—The Health DataResearch Hub for Respiratory Health (MC_PC_19004), which is funded through the UK Research and Innovation Industrial Strategy Challenge Fundand delivered through Health Data Research UK. The authors would like to acknowledge all other project collaborators not involved in these analyses but contributing to wider discussions and preceding outputs.
Issue: 1

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