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3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants

Eric Luis, Houwen Matthew Pan Orcid Logo, Anil Bastola Orcid Logo, Ram Bajpai Orcid Logo, Swee Leong Sing Orcid Logo, Juha Song, Wai Yee Yeong

Polymers, Volume: 12, Issue: 9, Start page: 2136

Swansea University Author: Anil Bastola Orcid Logo

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DOI (Published version): 10.3390/polym12092136

Abstract

Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implant...

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Published in: Polymers
ISSN: 2073-4360
Published: MDPI AG 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa65756
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spelling 2024-04-27T14:23:50.7789948 v2 65756 2024-03-05 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants 6775d40c935b36b92058eb10d6454f1a 0000-0002-5598-0849 Anil Bastola Anil Bastola true false 2024-03-05 ACEM Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples. Journal Article Polymers 12 9 2136 MDPI AG 2073-4360 additive manufacturing; 3D printing; silicone; meniscus implants; validation 18 9 2020 2020-09-18 10.3390/polym12092136 COLLEGE NANME Aerospace, Civil, Electrical, and Mechanical Engineering COLLEGE CODE ACEM Swansea University Another institution paid the OA fee This research is supported by the National Research Foundation, Prime Minister’s Office, Singapore under its Medium-Sized Center Funding scheme and the NTU Start-Up Grant. 2024-04-27T14:23:50.7789948 2024-03-05T22:00:19.2562961 Faculty of Science and Engineering School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Mechanical Engineering Eric Luis 1 Houwen Matthew Pan 0000-0003-4503-4581 2 Anil Bastola 0000-0002-5598-0849 3 Ram Bajpai 0000-0002-1227-2703 4 Swee Leong Sing 0000-0002-3980-6605 5 Juha Song 6 Wai Yee Yeong 7 65756__30167__7f4d8f24595f4247aa909d417b3c85b0.pdf 65756.VoR.pdf 2024-04-27T14:22:07.5536706 Output 6821081 application/pdf Version of Record true © 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. true eng http://creativecommons.org/licenses/by/4.0/
title 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
spellingShingle 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
Anil Bastola
title_short 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
title_full 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
title_fullStr 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
title_full_unstemmed 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
title_sort 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants
author_id_str_mv 6775d40c935b36b92058eb10d6454f1a
author_id_fullname_str_mv 6775d40c935b36b92058eb10d6454f1a_***_Anil Bastola
author Anil Bastola
author2 Eric Luis
Houwen Matthew Pan
Anil Bastola
Ram Bajpai
Swee Leong Sing
Juha Song
Wai Yee Yeong
format Journal article
container_title Polymers
container_volume 12
container_issue 9
container_start_page 2136
publishDate 2020
institution Swansea University
issn 2073-4360
doi_str_mv 10.3390/polym12092136
publisher MDPI AG
college_str Faculty of Science and Engineering
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hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Mechanical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Mechanical Engineering
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description Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples.
published_date 2020-09-18T02:26:28Z
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