Journal article 231 views
Silicone 3D Printing: Process Optimization, Product Biocompatibility, and Reliability of Silicone Meniscus Implants
,
Guo Dong Goh,
Guo Liang Goh,
Heang Kuan Joel Tan,
Ram Bajpai,
Juha Song,
Wai Yee Yeong
3D Printing and Additive Manufacturing, Volume: 6, Issue: 6, Pages: 319 - 332
Swansea University Author:
Anil Bastola
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1089/3dp.2018.0226
Abstract
A novel custom-made 3D silicone printer and two-part Ecoflex silicone resins were used to 3D-print standard-shaped silicone coupon and irregular-shaped meniscus structures via a heat-cured extrusion-based method. This article is segmented into three parts: (1) study on the effect of 3D printing para...
| Published in: | 3D Printing and Additive Manufacturing |
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| ISSN: | 2329-7662 2329-7670 |
| Published: |
Mary Ann Liebert Inc
2019
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa65753 |
| Abstract: |
A novel custom-made 3D silicone printer and two-part Ecoflex silicone resins were used to 3D-print standard-shaped silicone coupon and irregular-shaped meniscus structures via a heat-cured extrusion-based method. This article is segmented into three parts: (1) study on the effect of 3D printing parameters on dimensional accuracy and mechanical properties of 3D-printed silicone, (2) reliability and failure analysis of 3D-printed silicone according to ASTM D575 standards under monotonic and cyclic compressive loading, and (3) cytotoxicity of 3D-printed silicone by extraction method according to ISO 10993-12 for different extraction time and extract volume/surface area ratios. Based on analysis using regression method and analysis of variance, we found that the dimensional accuracy of lengths and widths is sensitive to both nozzle diameters and bed temperatures (BTs), while the height is only sensitive to BTs. Failure results were analyzed using the two-parameter Weibull probability distribution model and Weibull regression analysis and revealed that the Weibull modulus had a value greater than 1 in all groups, indicating an increasing failure rate with time for Ecoflex 30 and 50 meniscus implants. Results from quantitative cell proliferative assay exhibit statistically insignificant differences for all samples, pointing to the low cytotoxicity and excellent biocompatibility of printed silicone. |
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| College: |
Faculty of Science and Engineering |
| Funders: |
This research is supported by the National Research Foundation, Prime Minister's Office, Singapore, under its Medium-Sized Centre funding scheme and by the NTU Start-Up Grant. |
| Issue: |
6 |
| Start Page: |
319 |
| End Page: |
332 |