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Transient changes during microwave ablation simulation : a comparative shape analysis

DALE KERNOT, Jimmy Yang, Nicholas Williams, Tudor Thomas, Paul Ledger, Hari Arora Orcid Logo, Raoul van Loon Orcid Logo

Biomechanics and Modeling in Mechanobiology, Volume: 22

Swansea University Authors: DALE KERNOT, Hari Arora Orcid Logo, Raoul van Loon Orcid Logo

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DOI (Published version): 10.1007/s10237-022-01646-6

Abstract

Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption...

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Published in: Biomechanics and Modeling in Mechanobiology
ISSN: 1617-7959 1617-7940
Published: Springer Science and Business Media LLC 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa61532
first_indexed 2022-10-11T15:07:01Z
last_indexed 2024-11-14T12:19:15Z
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Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption rate fields throughout the course of simulated treatment with different probe concepts. Here, an axisymmetric geometry of a probe embedded within a tissue material is created, solving coupled electromagnetic and bioheat equations using the finite element method, utilizing hp discretisation with the NGSolve library. Results show dynamic changes across all metrics, with different responses from different probe concepts. The sleeve probe yielded the most circular specific absorption rate pattern with circularity of 0.81 initially but suffered the largest reduction throughout ablation. Similarly, reflection coefficients differ drastically from their initial values, with the sleeve probe again experiencing the largest change, suggesting that it is the most sensitive the changes in the tissue dielectric properties in these select probe designs. 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spelling 2023-06-12T17:08:31.8766795 v2 61532 2022-10-11 Transient changes during microwave ablation simulation : a comparative shape analysis c5212b8a5f533d2032d490b234c5e90a DALE KERNOT DALE KERNOT true false ed7371c768e9746008a6807f9f7a1555 0000-0002-9790-0907 Hari Arora Hari Arora true false 880b30f90841a022f1e5bac32fb12193 0000-0003-3581-5827 Raoul van Loon Raoul van Loon true false 2022-10-11 Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption rate fields throughout the course of simulated treatment with different probe concepts. Here, an axisymmetric geometry of a probe embedded within a tissue material is created, solving coupled electromagnetic and bioheat equations using the finite element method, utilizing hp discretisation with the NGSolve library. Results show dynamic changes across all metrics, with different responses from different probe concepts. The sleeve probe yielded the most circular specific absorption rate pattern with circularity of 0.81 initially but suffered the largest reduction throughout ablation. Similarly, reflection coefficients differ drastically from their initial values, with the sleeve probe again experiencing the largest change, suggesting that it is the most sensitive the changes in the tissue dielectric properties in these select probe designs. These collective characteristic observations highlight the need to consider dielectric property changes and probe specific responses during the design cycle. Journal Article Biomechanics and Modeling in Mechanobiology 22 Springer Science and Business Media LLC 1617-7959 1617-7940 Microwave ablation (MWA); Bioheat; Hyperthermal treatment; Numerical simulation; Shape analysis; Temperature sensitivity 26 10 2022 2022-10-26 10.1007/s10237-022-01646-6 COLLEGE NANME COLLEGE CODE Swansea University SU Library paid the OA fee (TA Institutional Deal) This work is part-funded by the European Social Fund through the European Union’s Convergence programme administered by the Welsh Government, and Olympus Surgical Technologies Europe. I would like to acknowledge the Engineering and Physical Sciences Research Council for their support through grant EP/V009028/1. Author DK received research support from Olympus Surgical Technologies Europe. 2023-06-12T17:08:31.8766795 2022-10-11T16:04:34.5164968 Faculty of Science and Engineering School of Engineering and Applied Sciences - Uncategorised DALE KERNOT 1 Jimmy Yang 2 Nicholas Williams 3 Tudor Thomas 4 Paul Ledger 5 Hari Arora 0000-0002-9790-0907 6 Raoul van Loon 0000-0003-3581-5827 7 61532__25604__434047e06dec4ff2ad142fa3243d9ccc.pdf 61532_VoR.pdf 2022-10-28T11:44:53.6047505 Output 1071088 application/pdf Version of Record true © The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License true eng http://creativecommons.org/licenses/by/4.0/
title Transient changes during microwave ablation simulation : a comparative shape analysis
spellingShingle Transient changes during microwave ablation simulation : a comparative shape analysis
DALE KERNOT
Hari Arora
Raoul van Loon
title_short Transient changes during microwave ablation simulation : a comparative shape analysis
title_full Transient changes during microwave ablation simulation : a comparative shape analysis
title_fullStr Transient changes during microwave ablation simulation : a comparative shape analysis
title_full_unstemmed Transient changes during microwave ablation simulation : a comparative shape analysis
title_sort Transient changes during microwave ablation simulation : a comparative shape analysis
author_id_str_mv c5212b8a5f533d2032d490b234c5e90a
ed7371c768e9746008a6807f9f7a1555
880b30f90841a022f1e5bac32fb12193
author_id_fullname_str_mv c5212b8a5f533d2032d490b234c5e90a_***_DALE KERNOT
ed7371c768e9746008a6807f9f7a1555_***_Hari Arora
880b30f90841a022f1e5bac32fb12193_***_Raoul van Loon
author DALE KERNOT
Hari Arora
Raoul van Loon
author2 DALE KERNOT
Jimmy Yang
Nicholas Williams
Tudor Thomas
Paul Ledger
Hari Arora
Raoul van Loon
format Journal article
container_title Biomechanics and Modeling in Mechanobiology
container_volume 22
publishDate 2022
institution Swansea University
issn 1617-7959
1617-7940
doi_str_mv 10.1007/s10237-022-01646-6
publisher Springer Science and Business Media LLC
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Uncategorised{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Uncategorised
document_store_str 1
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description Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region. Modelling can provide a prediction for the outcome of ablation, this paper explores changes in size and shape of temperature and Specific absorption rate fields throughout the course of simulated treatment with different probe concepts. Here, an axisymmetric geometry of a probe embedded within a tissue material is created, solving coupled electromagnetic and bioheat equations using the finite element method, utilizing hp discretisation with the NGSolve library. Results show dynamic changes across all metrics, with different responses from different probe concepts. The sleeve probe yielded the most circular specific absorption rate pattern with circularity of 0.81 initially but suffered the largest reduction throughout ablation. Similarly, reflection coefficients differ drastically from their initial values, with the sleeve probe again experiencing the largest change, suggesting that it is the most sensitive the changes in the tissue dielectric properties in these select probe designs. These collective characteristic observations highlight the need to consider dielectric property changes and probe specific responses during the design cycle.
published_date 2022-10-26T14:19:20Z
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score 11.048042

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