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Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: whole population cohort study in 46 million adults in England
William N Whiteley 
,
Samantha Ip,
Jennifer A Cooper ,
Thomas Bolton,
Spencer Keene ,
Venexia Walker ,
Rachel Denholm ,
Ashley Akbari ,
Efosa Omigie,
Sam Hollings,
Emanuele Di Angelantonio ,
Spiros Denaxas ,
Angela Wood ,
Jonathan A C Sterne ,
Cathie Sudlow ,
(CVD-COVID-UK consortium)
,
Samantha Ip,
Jennifer A Cooper ,
Thomas Bolton,
Spencer Keene ,
Venexia Walker ,
Rachel Denholm ,
Ashley Akbari ,
Efosa Omigie,
Sam Hollings,
Emanuele Di Angelantonio ,
Spiros Denaxas ,
Angela Wood ,
Jonathan A C Sterne ,
Cathie Sudlow ,
(CVD-COVID-UK consortium)
PLOS Medicine
Swansea University Author:
Ashley Akbari
-
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Copyright: © 2022 Whiteley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.
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DOI (Published version): 10.1371/journal.pmed.1003926
Abstract
Thromboses in unusual locations after the Coronavirus Disease 2019 (COVID-19) vaccine ChAdOx1-S have been reported, although their frequency with vaccines of different types is uncertain at a population level. The aim of this study was to estimate the population-level risks of hospitalised thrombocy...
| Published in: | PLOS Medicine |
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| ISSN: | 1549-1676 |
| Published: |
Cold Spring Harbor Laboratory
2022
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa57688 |
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| Abstract: |
Thromboses in unusual locations after the Coronavirus Disease 2019 (COVID-19) vaccine ChAdOx1-S have been reported, although their frequency with vaccines of different types is uncertain at a population level. The aim of this study was to estimate the population-level risks of hospitalised thrombocytopenia and major arterial and venous thromboses after COVID-19 vaccination. |
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| Item Description: |
Preprint article before certification by peer review: http://dx.doi.org/10.1101/2021.08.18.21262222 |
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
This work uses data provided by patients and collected by the NHS as part of their care and support. We would also like to acknowledge all data providers who make anonymised data available for research. |