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Graphene quantum dot–based electrochemical biosensing for early cancer detection

Tanveer A. Tabish, Hasan Hayat, Aumber Abbas, Roger J. Narayan

Current Opinion in Electrochemistry, Volume: 30, Start page: 100786

Swansea University Author: Hasan Hayat

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Abstract

Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations of biomarkers that distinguish...

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Published in: Current Opinion in Electrochemistry
ISSN: 2451-9103
Published: Elsevier BV 2021
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URI: https://cronfa.swan.ac.uk/Record/cronfa57163
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spelling 2021-07-16T12:55:52.6946087 v2 57163 2021-06-17 Graphene quantum dot–based electrochemical biosensing for early cancer detection bc4cb860540abc907d8a2271d564774d Hasan Hayat Hasan Hayat true false 2021-06-17 MTLS Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations of biomarkers that distinguish between normal and malignant cells. GQDs, known as a novel class of zero-dimensional semiconductor nanocrystals, are tiny graphene particles arranged in a honeycomb structure with a size range of 1-50 nm. The size of these GQDs is comparable to the size of biomolecules, thereby providing an ideal platform to study biomolecules such as proteins, cells, and viruses. GQDs are a superior platform for specific and sensitive recognition of cancer biomarkers; they are highly synergistic with electrochemical sensors. This review will shed light on the recent advancements made in the field of GQDs-based electrochemical sensors for early cancer detection, with the aim of highlighting the prospects for further development in cancer diagnostics. Journal Article Current Opinion in Electrochemistry 30 100786 Elsevier BV 2451-9103 Graphene quantum dot; Electrochemical biosensing; Cancer detection 1 12 2021 2021-12-01 10.1016/j.coelec.2021.100786 COLLEGE NANME Materials Science and Engineering COLLEGE CODE MTLS Swansea University 2021-07-16T12:55:52.6946087 2021-06-17T11:31:32.4418104 Faculty of Science and Engineering School of Engineering and Applied Sciences - Materials Science and Engineering Tanveer A. Tabish 1 Hasan Hayat 2 Aumber Abbas 3 Roger J. Narayan 4 57163__20184__390a0bdc022649caa12120127766a38e.pdf 57163.pdf 2021-06-17T11:33:10.6176917 Output 9105373 application/pdf Accepted Manuscript true 2022-06-16T00:00:00.0000000 Released under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License true eng http://creativecommons.org/licenses/by-nc-nd/4.0/
title Graphene quantum dot–based electrochemical biosensing for early cancer detection
spellingShingle Graphene quantum dot–based electrochemical biosensing for early cancer detection
Hasan Hayat
title_short Graphene quantum dot–based electrochemical biosensing for early cancer detection
title_full Graphene quantum dot–based electrochemical biosensing for early cancer detection
title_fullStr Graphene quantum dot–based electrochemical biosensing for early cancer detection
title_full_unstemmed Graphene quantum dot–based electrochemical biosensing for early cancer detection
title_sort Graphene quantum dot–based electrochemical biosensing for early cancer detection
author_id_str_mv bc4cb860540abc907d8a2271d564774d
author_id_fullname_str_mv bc4cb860540abc907d8a2271d564774d_***_Hasan Hayat
author Hasan Hayat
author2 Tanveer A. Tabish
Hasan Hayat
Aumber Abbas
Roger J. Narayan
format Journal article
container_title Current Opinion in Electrochemistry
container_volume 30
container_start_page 100786
publishDate 2021
institution Swansea University
issn 2451-9103
doi_str_mv 10.1016/j.coelec.2021.100786
publisher Elsevier BV
college_str Faculty of Science and Engineering
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hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Materials Science and Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Materials Science and Engineering
document_store_str 1
active_str 0
description Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations of biomarkers that distinguish between normal and malignant cells. GQDs, known as a novel class of zero-dimensional semiconductor nanocrystals, are tiny graphene particles arranged in a honeycomb structure with a size range of 1-50 nm. The size of these GQDs is comparable to the size of biomolecules, thereby providing an ideal platform to study biomolecules such as proteins, cells, and viruses. GQDs are a superior platform for specific and sensitive recognition of cancer biomarkers; they are highly synergistic with electrochemical sensors. This review will shed light on the recent advancements made in the field of GQDs-based electrochemical sensors for early cancer detection, with the aim of highlighting the prospects for further development in cancer diagnostics.
published_date 2021-12-01T04:12:41Z
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