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Graphene quantum dot–based electrochemical biosensing for early cancer detection

Tanveer A. Tabish, Hasan Hayat, Aumber Abbas, Roger J. Narayan

Current Opinion in Electrochemistry, Volume: 30, Start page: 100786

Swansea University Author: Hasan Hayat

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DOI (Published version): 10.1016/j.coelec.2021.100786

Abstract

Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations of biomarkers that distinguish...

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Published in: Current Opinion in Electrochemistry
ISSN: 2451-9103
Published: Elsevier BV 2021
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa57163
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Abstract: Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations of biomarkers that distinguish between normal and malignant cells. GQDs, known as a novel class of zero-dimensional semiconductor nanocrystals, are tiny graphene particles arranged in a honeycomb structure with a size range of 1-50 nm. The size of these GQDs is comparable to the size of biomolecules, thereby providing an ideal platform to study biomolecules such as proteins, cells, and viruses. GQDs are a superior platform for specific and sensitive recognition of cancer biomarkers; they are highly synergistic with electrochemical sensors. This review will shed light on the recent advancements made in the field of GQDs-based electrochemical sensors for early cancer detection, with the aim of highlighting the prospects for further development in cancer diagnostics.
Keywords: Graphene quantum dot; Electrochemical biosensing; Cancer detection
College: Faculty of Science and Engineering
Start Page: 100786

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