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3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
Romeo Romagnoli,
Filippo Prencipe,
Paola Oliva,
Stefania Baraldi,
Pier Giovanni Baraldi,
Andrea Brancale,
Salvatore Ferla ,
Ernest Hamel,
Roberta Bortolozzi,
Giampietro Viola
Bioorganic Chemistry, Volume: 80, Pages: 361 - 374
Swansea University Author: Salvatore Ferla
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DOI (Published version): 10.1016/j.bioorg.2018.06.037
Abstract
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
Published in: | Bioorganic Chemistry |
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ISSN: | 0045-2068 |
Published: |
Elsevier BV
2018
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Online Access: |
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URI: | https://cronfa.swan.ac.uk/Record/cronfa55466 |
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2020-10-20T15:02:19Z |
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2020-12-12T04:20:03Z |
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2020-12-11T17:07:45.9374238 v2 55466 2020-10-20 3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization d4c62248f510e3b221916989a7bbe6a6 0000-0002-5918-9237 Salvatore Ferla Salvatore Ferla true false 2020-10-20 MEDS Journal Article Bioorganic Chemistry 80 361 374 Elsevier BV 0045-2068 Microtubule targeting-agent; Structure-activity relationship; Tubulin polymerization; Antiproliferative activity; Molecular docking 1 10 2018 2018-10-01 10.1016/j.bioorg.2018.06.037 http://orca.cf.ac.uk/113241/ COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2020-12-11T17:07:45.9374238 2020-10-20T16:01:58.5170967 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Romeo Romagnoli 1 Filippo Prencipe 2 Paola Oliva 3 Stefania Baraldi 4 Pier Giovanni Baraldi 5 Andrea Brancale 6 Salvatore Ferla 0000-0002-5918-9237 7 Ernest Hamel 8 Roberta Bortolozzi 9 Giampietro Viola 10 |
title |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
spellingShingle |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization Salvatore Ferla |
title_short |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
title_full |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
title_fullStr |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
title_full_unstemmed |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
title_sort |
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization |
author_id_str_mv |
d4c62248f510e3b221916989a7bbe6a6 |
author_id_fullname_str_mv |
d4c62248f510e3b221916989a7bbe6a6_***_Salvatore Ferla |
author |
Salvatore Ferla |
author2 |
Romeo Romagnoli Filippo Prencipe Paola Oliva Stefania Baraldi Pier Giovanni Baraldi Andrea Brancale Salvatore Ferla Ernest Hamel Roberta Bortolozzi Giampietro Viola |
format |
Journal article |
container_title |
Bioorganic Chemistry |
container_volume |
80 |
container_start_page |
361 |
publishDate |
2018 |
institution |
Swansea University |
issn |
0045-2068 |
doi_str_mv |
10.1016/j.bioorg.2018.06.037 |
publisher |
Elsevier BV |
college_str |
Faculty of Medicine, Health and Life Sciences |
hierarchytype |
|
hierarchy_top_id |
facultyofmedicinehealthandlifesciences |
hierarchy_top_title |
Faculty of Medicine, Health and Life Sciences |
hierarchy_parent_id |
facultyofmedicinehealthandlifesciences |
hierarchy_parent_title |
Faculty of Medicine, Health and Life Sciences |
department_str |
Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine |
url |
http://orca.cf.ac.uk/113241/ |
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0 |
active_str |
0 |
published_date |
2018-10-01T19:57:32Z |
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1821346158077804544 |
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11.04748 |