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Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease

Michael Lewis, Joe Annandale, Keir Lewis Orcid Logo

Clinical Physiology and Functional Imaging, Volume: 29, Issue: 6, Pages: 431 - 439

Swansea University Authors: Michael Lewis, Keir Lewis Orcid Logo

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DOI (Published version): 10.1111/j.1475-097X.2009.00891.x

Published in: Clinical Physiology and Functional Imaging
Published: 2009
URI: https://cronfa.swan.ac.uk/Record/cronfa5530
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first_indexed 2013-07-23T11:52:55Z
last_indexed 2018-02-09T04:31:54Z
id cronfa5530
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fullrecord <?xml version="1.0"?><rfc1807><datestamp>2016-08-15T09:55:05.6928443</datestamp><bib-version>v2</bib-version><id>5530</id><entry>2013-09-03</entry><title>Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease</title><swanseaauthors><author><sid>b59c8f5c056bac7e6995385f22ad1639</sid><firstname>Michael</firstname><surname>Lewis</surname><name>Michael Lewis</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>bc53c343c975d6e0ad88c1d8b9ddd70c</sid><ORCID>0000-0002-8248-6774</ORCID><firstname>Keir</firstname><surname>Lewis</surname><name>Keir Lewis</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2013-09-03</date><deptcode>FGSEN</deptcode><abstract></abstract><type>Journal Article</type><journal>Clinical Physiology and Functional Imaging</journal><volume>29</volume><journalNumber>6</journalNumber><paginationStart>431</paginationStart><paginationEnd>439</paginationEnd><publisher/><issnPrint/><keywords/><publishedDay>31</publishedDay><publishedMonth>12</publishedMonth><publishedYear>2009</publishedYear><publishedDate>2009-12-31</publishedDate><doi>10.1111/j.1475-097X.2009.00891.x</doi><url/><notes>The novelty of this work was that it was the first to report cardiac benefits of long-term oxygen therapy (LTOT) in chronic obstructive pulmonary disease (COPD), demonstrated here through time-dependent reversal of autonomic nervous system depression. A rigorous pre-post clinical intervention study design and advanced time-series analysis methods provided evidence to support additional cardiac benefits of LTOT. The work led to further clinical collaborations to establish the cardio-pulmonary pathophysiology underlying COPD. This and companion works fostered the knowledge underpinning a major industrial collaboration with Haemair Ltd. (CIRP/A4B grant HE09COL1029) to empirically model a control system for an artificial lung device.</notes><college>COLLEGE NANME</college><department>Science and Engineering - Faculty</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>FGSEN</DepartmentCode><institution>Swansea University</institution><apcterm/><lastEdited>2016-08-15T09:55:05.6928443</lastEdited><Created>2013-09-03T06:10:55.0000000</Created><path><level id="1">Faculty of Science and Engineering</level><level id="2">School of Engineering and Applied Sciences - Uncategorised</level></path><authors><author><firstname>Michael</firstname><surname>Lewis</surname><order>1</order></author><author><firstname>Joe</firstname><surname>Annandale</surname><order>2</order></author><author><firstname>Keir</firstname><surname>Lewis</surname><orcid>0000-0002-8248-6774</orcid><order>3</order></author></authors><documents/><OutputDurs/></rfc1807>
spelling 2016-08-15T09:55:05.6928443 v2 5530 2013-09-03 Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease b59c8f5c056bac7e6995385f22ad1639 Michael Lewis Michael Lewis true false bc53c343c975d6e0ad88c1d8b9ddd70c 0000-0002-8248-6774 Keir Lewis Keir Lewis true false 2013-09-03 FGSEN Journal Article Clinical Physiology and Functional Imaging 29 6 431 439 31 12 2009 2009-12-31 10.1111/j.1475-097X.2009.00891.x The novelty of this work was that it was the first to report cardiac benefits of long-term oxygen therapy (LTOT) in chronic obstructive pulmonary disease (COPD), demonstrated here through time-dependent reversal of autonomic nervous system depression. A rigorous pre-post clinical intervention study design and advanced time-series analysis methods provided evidence to support additional cardiac benefits of LTOT. The work led to further clinical collaborations to establish the cardio-pulmonary pathophysiology underlying COPD. This and companion works fostered the knowledge underpinning a major industrial collaboration with Haemair Ltd. (CIRP/A4B grant HE09COL1029) to empirically model a control system for an artificial lung device. COLLEGE NANME Science and Engineering - Faculty COLLEGE CODE FGSEN Swansea University 2016-08-15T09:55:05.6928443 2013-09-03T06:10:55.0000000 Faculty of Science and Engineering School of Engineering and Applied Sciences - Uncategorised Michael Lewis 1 Joe Annandale 2 Keir Lewis 0000-0002-8248-6774 3
title Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
spellingShingle Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
Michael Lewis
Keir Lewis
title_short Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_full Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_fullStr Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_full_unstemmed Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
title_sort Influence of long-term oxygen therapy on heart rate and QT time-series in hypoxic patients with chronic obstructive pulmonary disease
author_id_str_mv b59c8f5c056bac7e6995385f22ad1639
bc53c343c975d6e0ad88c1d8b9ddd70c
author_id_fullname_str_mv b59c8f5c056bac7e6995385f22ad1639_***_Michael Lewis
bc53c343c975d6e0ad88c1d8b9ddd70c_***_Keir Lewis
author Michael Lewis
Keir Lewis
author2 Michael Lewis
Joe Annandale
Keir Lewis
format Journal article
container_title Clinical Physiology and Functional Imaging
container_volume 29
container_issue 6
container_start_page 431
publishDate 2009
institution Swansea University
doi_str_mv 10.1111/j.1475-097X.2009.00891.x
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Uncategorised{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Uncategorised
document_store_str 0
active_str 0
published_date 2009-12-31T03:06:39Z
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score 11.013148

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