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Relating quantitative variation within a behavior to variation in transcription

Kyle M. Benowitz, Elizabeth C. McKinney, Christopher B. Cunningham, Allen J. Moore, Chris Cunningham Orcid Logo

Evolution, Volume: 71, Issue: 8, Pages: 1999 - 2009

Swansea University Author: Chris Cunningham Orcid Logo

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DOI (Published version): 10.1111/evo.13273

Abstract

Many studies have shown that variation in transcription is associated with changes in behavioral state, or with variation within a state, but little has been done to address if the same genes are involved in both. Here we investigate the transcriptional basis of variation in parental provisioning us...

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Published in: Evolution
ISSN: 00143820
Published: 2017
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URI: https://cronfa.swan.ac.uk/Record/cronfa37746
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spelling 2018-04-12T10:20:57.3065288 v2 37746 2017-12-30 Relating quantitative variation within a behavior to variation in transcription 0bd688baf9fc30cb39dfae9ed28cb662 0000-0003-3965-2076 Chris Cunningham Chris Cunningham true false 2017-12-30 SBI Many studies have shown that variation in transcription is associated with changes in behavioral state, or with variation within a state, but little has been done to address if the same genes are involved in both. Here we investigate the transcriptional basis of variation in parental provisioning using two species of burying beetle, Nicrophorus orbicollis and Nicrophorus vespilloides. We used RNA-seq to compare transcription in parents that provided high amounts of provisioning behavior versus low amounts in males and females of each species. We found no overarching transcriptional patterns distinguishing high from low caring parents, and no informative transcripts that displayed particularly large expression differences in either sex. However, we did find subtler gene expression differences between high and low provisioning parents that are consistent across both sexes and species. Furthermore, we show that transcripts previously implicated in transitioning into parental care in N. vespilloides had high variance in the levels of transcription and were unusually likely to display differential expression between high and low provisioning parents. Thus, quantitative behavioral variation appears to reflect many transcriptional differences of small effect. Furthermore, the same transcripts required for the transition between behavioral states are also related to variation within a behavioral state. Journal Article Evolution 71 8 1999 2009 00143820 burying beetle, gene set enrichment analysis, Nicrophorus, parental care, quantitative trait transcripts, RNA-seq 31 12 2017 2017-12-31 10.1111/evo.13273 COLLEGE NANME Biosciences COLLEGE CODE SBI Swansea University 2018-04-12T10:20:57.3065288 2017-12-30T00:35:50.1964930 Faculty of Science and Engineering School of Biosciences, Geography and Physics - Biosciences Kyle M. Benowitz 1 Elizabeth C. McKinney 2 Christopher B. Cunningham 3 Allen J. Moore 4 Chris Cunningham 0000-0003-3965-2076 5 0037746-30122017003649.pdf behavvar,transvar,BB,accepted;Moore(2017).pdf 2017-12-30T00:36:49.2470000 Output 1313496 application/pdf Accepted Manuscript true 2018-06-08T00:00:00.0000000 true eng
title Relating quantitative variation within a behavior to variation in transcription
spellingShingle Relating quantitative variation within a behavior to variation in transcription
Chris Cunningham
title_short Relating quantitative variation within a behavior to variation in transcription
title_full Relating quantitative variation within a behavior to variation in transcription
title_fullStr Relating quantitative variation within a behavior to variation in transcription
title_full_unstemmed Relating quantitative variation within a behavior to variation in transcription
title_sort Relating quantitative variation within a behavior to variation in transcription
author_id_str_mv 0bd688baf9fc30cb39dfae9ed28cb662
author_id_fullname_str_mv 0bd688baf9fc30cb39dfae9ed28cb662_***_Chris Cunningham
author Chris Cunningham
author2 Kyle M. Benowitz
Elizabeth C. McKinney
Christopher B. Cunningham
Allen J. Moore
Chris Cunningham
format Journal article
container_title Evolution
container_volume 71
container_issue 8
container_start_page 1999
publishDate 2017
institution Swansea University
issn 00143820
doi_str_mv 10.1111/evo.13273
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Biosciences, Geography and Physics - Biosciences{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Biosciences, Geography and Physics - Biosciences
document_store_str 1
active_str 0
description Many studies have shown that variation in transcription is associated with changes in behavioral state, or with variation within a state, but little has been done to address if the same genes are involved in both. Here we investigate the transcriptional basis of variation in parental provisioning using two species of burying beetle, Nicrophorus orbicollis and Nicrophorus vespilloides. We used RNA-seq to compare transcription in parents that provided high amounts of provisioning behavior versus low amounts in males and females of each species. We found no overarching transcriptional patterns distinguishing high from low caring parents, and no informative transcripts that displayed particularly large expression differences in either sex. However, we did find subtler gene expression differences between high and low provisioning parents that are consistent across both sexes and species. Furthermore, we show that transcripts previously implicated in transitioning into parental care in N. vespilloides had high variance in the levels of transcription and were unusually likely to display differential expression between high and low provisioning parents. Thus, quantitative behavioral variation appears to reflect many transcriptional differences of small effect. Furthermore, the same transcripts required for the transition between behavioral states are also related to variation within a behavioral state.
published_date 2017-12-31T03:47:34Z
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score 11.036684

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