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Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes

Benjamin Eagle, David J. Williams, John Dingley

Anesthesia & Analgesia, Volume: 125, Issue: 2, Pages: 458 - 466

Swansea University Author: John Dingley

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DOI (Published version): 10.1213/ANE.0000000000002172

Abstract

Background:An ideal electronic anesthesia recording system would be capable of not only recording physiological data but also injectable drug doses given including those given incrementally from one syringe, without recourse to manual data entry. We compared two prototype devices which wirelessly re...

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Published in: Anesthesia & Analgesia
ISSN: 0003-2999
Published: 2017
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URI: https://cronfa.swan.ac.uk/Record/cronfa32993
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fullrecord <?xml version="1.0"?><rfc1807><datestamp>2019-06-12T15:47:18.7650305</datestamp><bib-version>v2</bib-version><id>32993</id><entry>2017-04-12</entry><title>Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes</title><swanseaauthors><author><sid>1283ffdd09b091ec57ec3e235a48cfcc</sid><firstname>John</firstname><surname>Dingley</surname><name>John Dingley</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2017-04-12</date><deptcode>PMSC</deptcode><abstract>Background:An ideal electronic anesthesia recording system would be capable of not only recording physiological data but also injectable drug doses given including those given incrementally from one syringe, without recourse to manual data entry. We compared two prototype devices which wirelessly recognised individual syringes and measured changes in their plunger positions via two different optical non-contact means, allowing calculation of incremental drug doses given.Methods:Both devices incorporated a Radio-Frequency Identification (RFID) reader which wirelessly read a unique code from an RFID tag within syringe drug labels. A custom designed cradle, oriented any inserted 1ml to 20ml syringe in a repeatable position. The "Laser" device had a moving laser beam broken by the end of the syringe plunger. The infra-red "IR" device measured time of travel of infra-red light from a sender to syringe plunger and back to a receiver. Both devices could therefore determine the drug and volume administered since the previous occasion any syringe had been used. For each syringe size of 1 ml, 2ml, 5ml, 10ml and 20 ml, 121 plunger length measurements were made over their full range with each machine against a reference method of water filling and weighing, using a randomised de Bruijn sequence.Results:For every syringe size, the Laser device showed greater accuracy and precision, lower bias and narrower Limits of Agreement (95% confidence intervals = bias +/- 1.96 SD) than the IR device when compared to the reference method. For all syringe sizes, the range of bias was -0.05 ml to 0.32 ml for the Laser, and -2.42 ml to 1.38 ml for the IR. Lin's Concordance Correlation Coefficient values for the IR versus reference methods ranged from 0.6259 to 0.9255 with the lowest co-efficients seen in syringes with the shortest distance of plunger travel (2ml and 5ml) while in Laser versus reference comparisons, these coefficients were similar (0.9641 - 0.9981) over all syringe lengths.Conclusions:Both devices measured syringe volume changes, demonstrating potential for measuring incremental drug doses, recording these and also the time of each measurement. The IR device had no moving parts which would be advantageous in a clinical situation. However the current embodiment was not deemed accurate enough for clinical use, potentially remediable through improvements in hardware and software design. The laser device showed high accuracy and precision over all syringe sizes and contained volumes and was considered potentially accurate enough for clinical use with suitable development.</abstract><type>Journal Article</type><journal>Anesthesia &amp; Analgesia</journal><volume>125</volume><journalNumber>2</journalNumber><paginationStart>458</paginationStart><paginationEnd>466</paginationEnd><publisher/><issnPrint>0003-2999</issnPrint><keywords/><publishedDay>1</publishedDay><publishedMonth>8</publishedMonth><publishedYear>2017</publishedYear><publishedDate>2017-08-01</publishedDate><doi>10.1213/ANE.0000000000002172</doi><url/><notes/><college>COLLEGE NANME</college><department>Medicine</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>PMSC</DepartmentCode><institution>Swansea University</institution><apcterm/><lastEdited>2019-06-12T15:47:18.7650305</lastEdited><Created>2017-04-12T21:06:59.9157093</Created><path><level id="1">Faculty of Medicine, Health and Life Sciences</level><level id="2">Swansea University Medical School - Medicine</level></path><authors><author><firstname>Benjamin</firstname><surname>Eagle</surname><order>1</order></author><author><firstname>David J.</firstname><surname>Williams</surname><order>2</order></author><author><firstname>John</firstname><surname>Dingley</surname><order>3</order></author></authors><documents/><OutputDurs/></rfc1807>
spelling 2019-06-12T15:47:18.7650305 v2 32993 2017-04-12 Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes 1283ffdd09b091ec57ec3e235a48cfcc John Dingley John Dingley true false 2017-04-12 PMSC Background:An ideal electronic anesthesia recording system would be capable of not only recording physiological data but also injectable drug doses given including those given incrementally from one syringe, without recourse to manual data entry. We compared two prototype devices which wirelessly recognised individual syringes and measured changes in their plunger positions via two different optical non-contact means, allowing calculation of incremental drug doses given.Methods:Both devices incorporated a Radio-Frequency Identification (RFID) reader which wirelessly read a unique code from an RFID tag within syringe drug labels. A custom designed cradle, oriented any inserted 1ml to 20ml syringe in a repeatable position. The "Laser" device had a moving laser beam broken by the end of the syringe plunger. The infra-red "IR" device measured time of travel of infra-red light from a sender to syringe plunger and back to a receiver. Both devices could therefore determine the drug and volume administered since the previous occasion any syringe had been used. For each syringe size of 1 ml, 2ml, 5ml, 10ml and 20 ml, 121 plunger length measurements were made over their full range with each machine against a reference method of water filling and weighing, using a randomised de Bruijn sequence.Results:For every syringe size, the Laser device showed greater accuracy and precision, lower bias and narrower Limits of Agreement (95% confidence intervals = bias +/- 1.96 SD) than the IR device when compared to the reference method. For all syringe sizes, the range of bias was -0.05 ml to 0.32 ml for the Laser, and -2.42 ml to 1.38 ml for the IR. Lin's Concordance Correlation Coefficient values for the IR versus reference methods ranged from 0.6259 to 0.9255 with the lowest co-efficients seen in syringes with the shortest distance of plunger travel (2ml and 5ml) while in Laser versus reference comparisons, these coefficients were similar (0.9641 - 0.9981) over all syringe lengths.Conclusions:Both devices measured syringe volume changes, demonstrating potential for measuring incremental drug doses, recording these and also the time of each measurement. The IR device had no moving parts which would be advantageous in a clinical situation. However the current embodiment was not deemed accurate enough for clinical use, potentially remediable through improvements in hardware and software design. The laser device showed high accuracy and precision over all syringe sizes and contained volumes and was considered potentially accurate enough for clinical use with suitable development. Journal Article Anesthesia & Analgesia 125 2 458 466 0003-2999 1 8 2017 2017-08-01 10.1213/ANE.0000000000002172 COLLEGE NANME Medicine COLLEGE CODE PMSC Swansea University 2019-06-12T15:47:18.7650305 2017-04-12T21:06:59.9157093 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Benjamin Eagle 1 David J. Williams 2 John Dingley 3
title Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
spellingShingle Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
John Dingley
title_short Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
title_full Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
title_fullStr Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
title_full_unstemmed Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
title_sort Investigation of Two Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes
author_id_str_mv 1283ffdd09b091ec57ec3e235a48cfcc
author_id_fullname_str_mv 1283ffdd09b091ec57ec3e235a48cfcc_***_John Dingley
author John Dingley
author2 Benjamin Eagle
David J. Williams
John Dingley
format Journal article
container_title Anesthesia & Analgesia
container_volume 125
container_issue 2
container_start_page 458
publishDate 2017
institution Swansea University
issn 0003-2999
doi_str_mv 10.1213/ANE.0000000000002172
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description Background:An ideal electronic anesthesia recording system would be capable of not only recording physiological data but also injectable drug doses given including those given incrementally from one syringe, without recourse to manual data entry. We compared two prototype devices which wirelessly recognised individual syringes and measured changes in their plunger positions via two different optical non-contact means, allowing calculation of incremental drug doses given.Methods:Both devices incorporated a Radio-Frequency Identification (RFID) reader which wirelessly read a unique code from an RFID tag within syringe drug labels. A custom designed cradle, oriented any inserted 1ml to 20ml syringe in a repeatable position. The "Laser" device had a moving laser beam broken by the end of the syringe plunger. The infra-red "IR" device measured time of travel of infra-red light from a sender to syringe plunger and back to a receiver. Both devices could therefore determine the drug and volume administered since the previous occasion any syringe had been used. For each syringe size of 1 ml, 2ml, 5ml, 10ml and 20 ml, 121 plunger length measurements were made over their full range with each machine against a reference method of water filling and weighing, using a randomised de Bruijn sequence.Results:For every syringe size, the Laser device showed greater accuracy and precision, lower bias and narrower Limits of Agreement (95% confidence intervals = bias +/- 1.96 SD) than the IR device when compared to the reference method. For all syringe sizes, the range of bias was -0.05 ml to 0.32 ml for the Laser, and -2.42 ml to 1.38 ml for the IR. Lin's Concordance Correlation Coefficient values for the IR versus reference methods ranged from 0.6259 to 0.9255 with the lowest co-efficients seen in syringes with the shortest distance of plunger travel (2ml and 5ml) while in Laser versus reference comparisons, these coefficients were similar (0.9641 - 0.9981) over all syringe lengths.Conclusions:Both devices measured syringe volume changes, demonstrating potential for measuring incremental drug doses, recording these and also the time of each measurement. The IR device had no moving parts which would be advantageous in a clinical situation. However the current embodiment was not deemed accurate enough for clinical use, potentially remediable through improvements in hardware and software design. The laser device showed high accuracy and precision over all syringe sizes and contained volumes and was considered potentially accurate enough for clinical use with suitable development.
published_date 2017-08-01T03:40:36Z
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score 11.037581

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