Journal article 628 views
Role of the inter-protofilament sliding in the bending of protein microtubules
Chengyuan Wang,
Zhigang Guo,
Ruijie Wang,
Ying Luo
Journal of Biomechanics, Volume: 49, Issue: 16, Pages: 3803 - 3807
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DOI (Published version): 10.1016/j.jbiomech.2016.10.008
Abstract
This paper aims to identify the role of the inter-protofilament (PF) sliding in the bending of microtubules (MTs). A molecular structural model (MSM) was employed to study the dependence of bending on the inter-PF bonds. It was found that the inter-PF bonds serve as an angle spring that controls the...
| Published in: | Journal of Biomechanics |
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| ISSN: | 0021-9290 |
| Published: |
2016
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa30719 |
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| Abstract: |
This paper aims to identify the role of the inter-protofilament (PF) sliding in the bending of microtubules (MTs). A molecular structural model (MSM) was employed to study the dependence of bending on the inter-PF bonds. It was found that the inter-PF bonds serve as an angle spring that controls the inter-PF sliding during the bending. When the angle spring is soft inter-PF sliding occurs leading to the length-dependent bending stiffness of MTs. Such a size dependent bending stiffness may also affect the vibration and buckling behavior of MTs where bending deformation is predominant. |
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| College: |
College of Engineering |
| Issue: |
16 |
| Start Page: |
3803 |
| End Page: |
3807 |