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Derivation from First Principles of the Statistical Distribution of the Mass Peak Intensities of MS Data

Andreas Ipsen

Analytical Chemistry, Volume: 87, Issue: 3, Pages: 1726 - 1734

Swansea University Author: Andreas Ipsen

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DOI (Published version): 10.1021/ac503554u

Abstract

The statistical distribution of mass peak intensities recorded on instruments employing analog-to-digital converters (ADCs) and electron multipliers is derived from the first principles of the data generation process. The resulting Gaussian model is validated with experimental data.

Published in: Analytical Chemistry
Published: 2015
URI: https://cronfa.swan.ac.uk/Record/cronfa22259
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Abstract: The statistical distribution of mass peak intensities recorded on instruments employing analog-to-digital converters (ADCs) and electron multipliers is derived from the first principles of the data generation process. The resulting Gaussian model is validated with experimental data.
Keywords: mass spectrometry, mass peak intensity, statistical distribution
College: Faculty of Medicine, Health and Life Sciences
Issue: 3
Start Page: 1726
End Page: 1734