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Synthesis of the Asperparaline Core by a Radical Cascade

Peter Crick, Nigel S Simpkins, Adrian Highton

Organic Letters, Volume: 13, Issue: 24, Pages: 6472 - 6475

Swansea University Author: Peter Crick

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DOI (Published version): 10.1021/ol202769f

Abstract

A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.

Published in: Organic Letters
ISSN: 1523-7060 1523-7052
Published: 2011
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa15144
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spelling 2013-11-08T10:29:50.0420700 v2 15144 2013-06-28 Synthesis of the Asperparaline Core by a Radical Cascade 9e8253a728dc2ad7303ee8928fc85560 Peter Crick Peter Crick true false 2013-06-28 A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations. Journal Article Organic Letters 13 24 6472 6475 1523-7060 1523-7052 31 12 2011 2011-12-31 10.1021/ol202769f COLLEGE NANME COLLEGE CODE Swansea University 2013-11-08T10:29:50.0420700 2013-06-28T13:01:07.2649673 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Peter Crick 1 Nigel S Simpkins 2 Adrian Highton 3
title Synthesis of the Asperparaline Core by a Radical Cascade
spellingShingle Synthesis of the Asperparaline Core by a Radical Cascade
Peter Crick
title_short Synthesis of the Asperparaline Core by a Radical Cascade
title_full Synthesis of the Asperparaline Core by a Radical Cascade
title_fullStr Synthesis of the Asperparaline Core by a Radical Cascade
title_full_unstemmed Synthesis of the Asperparaline Core by a Radical Cascade
title_sort Synthesis of the Asperparaline Core by a Radical Cascade
author_id_str_mv 9e8253a728dc2ad7303ee8928fc85560
author_id_fullname_str_mv 9e8253a728dc2ad7303ee8928fc85560_***_Peter Crick
author Peter Crick
author2 Peter Crick
Nigel S Simpkins
Adrian Highton
format Journal article
container_title Organic Letters
container_volume 13
container_issue 24
container_start_page 6472
publishDate 2011
institution Swansea University
issn 1523-7060
1523-7052
doi_str_mv 10.1021/ol202769f
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
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description A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.
published_date 2011-12-31T03:26:00Z
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score 11.090071