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Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study

S Brophy, H Davies, Jeffrey Stephens Orcid Logo, Sarah Prior Orcid Logo, M Atkinson, Steve Bain, R Williams, Helen Davies, Sinead Brophy Orcid Logo, Mark Atkinson Orcid Logo

BMC Research Notes, Volume: 3, Start page: 317

Swansea University Authors: Jeffrey Stephens Orcid Logo, Sarah Prior Orcid Logo, Helen Davies, Sinead Brophy Orcid Logo, Mark Atkinson Orcid Logo

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DOI (Published version): 10.1186/1756-0500-3-317

Abstract

To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the L...

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Published in: BMC Research Notes
Published: 2010
Online Access: http://www.biomedcentral.com/1756-0500/3/317/abstract
URI: https://cronfa.swan.ac.uk/Record/cronfa10727
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spelling 2014-12-05T14:47:21.3962855 v2 10727 2012-05-09 Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study 5219d126f97f8f884bdb622099bd41de 0000-0003-2228-086X Jeffrey Stephens Jeffrey Stephens true false cdda101035997acfaa6fdf17097f52b2 0000-0001-8703-8092 Sarah Prior Sarah Prior true false 73508839e5f4da48f5001240fd834e4b Helen Davies Helen Davies true false 84f5661b35a729f55047f9e793d8798b 0000-0001-7417-2858 Sinead Brophy Sinead Brophy true false 8f85ae301cc97a48eaf58fe343c5a797 0000-0003-4237-3588 Mark Atkinson Mark Atkinson true false 2012-05-09 BMS To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the LADA patients' versus controls. The average adiponectin level for the LADA patients was 9.96 μg/ml compared to 6.4 μg/ml for Type 2 matched controls and 9.6 μg/ml for non-diabetic controls. Mean difference for the LADA-type 2 comparison was calculated after data was log transformed and showed a difference of 1.58 μg/ml (95%CI: 1.28-1.95, p = 0.0001). There was no significant difference between LADA and non-diabetic controls (p = 0.54). Adiponectin levels are higher among people with LADA compared to those with type 2 diabetes and are equivalent to levels seen in non-diabetic controls. This suggests that risk of complications in LADA, as with type 1 diabetes may be related more to glycaemic control rather than to factors of the metabolic syndrome. Journal Article BMC Research Notes 3 317 31 12 2010 2010-12-31 10.1186/1756-0500-3-317 http://www.biomedcentral.com/1756-0500/3/317/abstract COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University 2014-12-05T14:47:21.3962855 2012-05-09T09:46:04.6837473 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine S Brophy 1 H Davies 2 Jeffrey Stephens 0000-0003-2228-086X 3 Sarah Prior 0000-0001-8703-8092 4 M Atkinson 5 Steve Bain 6 R Williams 7 Helen Davies 8 Sinead Brophy 0000-0001-7417-2858 9 Mark Atkinson 0000-0003-4237-3588 10
title Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
spellingShingle Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
Jeffrey Stephens
Sarah Prior
Helen Davies
Sinead Brophy
Mark Atkinson
title_short Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
title_full Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
title_fullStr Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
title_full_unstemmed Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
title_sort Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
author_id_str_mv 5219d126f97f8f884bdb622099bd41de
cdda101035997acfaa6fdf17097f52b2
73508839e5f4da48f5001240fd834e4b
84f5661b35a729f55047f9e793d8798b
8f85ae301cc97a48eaf58fe343c5a797
author_id_fullname_str_mv 5219d126f97f8f884bdb622099bd41de_***_Jeffrey Stephens
cdda101035997acfaa6fdf17097f52b2_***_Sarah Prior
73508839e5f4da48f5001240fd834e4b_***_Helen Davies
84f5661b35a729f55047f9e793d8798b_***_Sinead Brophy
8f85ae301cc97a48eaf58fe343c5a797_***_Mark Atkinson
author Jeffrey Stephens
Sarah Prior
Helen Davies
Sinead Brophy
Mark Atkinson
author2 S Brophy
H Davies
Jeffrey Stephens
Sarah Prior
M Atkinson
Steve Bain
R Williams
Helen Davies
Sinead Brophy
Mark Atkinson
format Journal article
container_title BMC Research Notes
container_volume 3
container_start_page 317
publishDate 2010
institution Swansea University
doi_str_mv 10.1186/1756-0500-3-317
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
url http://www.biomedcentral.com/1756-0500/3/317/abstract
document_store_str 0
active_str 0
description To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the LADA patients' versus controls. The average adiponectin level for the LADA patients was 9.96 μg/ml compared to 6.4 μg/ml for Type 2 matched controls and 9.6 μg/ml for non-diabetic controls. Mean difference for the LADA-type 2 comparison was calculated after data was log transformed and showed a difference of 1.58 μg/ml (95%CI: 1.28-1.95, p = 0.0001). There was no significant difference between LADA and non-diabetic controls (p = 0.54). Adiponectin levels are higher among people with LADA compared to those with type 2 diabetes and are equivalent to levels seen in non-diabetic controls. This suggests that risk of complications in LADA, as with type 1 diabetes may be related more to glycaemic control rather than to factors of the metabolic syndrome.
published_date 2010-12-31T03:12:11Z
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