Journal article 1360 views
Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study
,
Sarah Prior ,
M Atkinson,
Steve Bain,
R Williams,
Helen Davies,
Sinead Brophy ,
Mark Atkinson
BMC Research Notes, Volume: 3, Start page: 317
Swansea University Authors:
Jeffrey Stephens , Sarah Prior , Helen Davies, Sinead Brophy , Mark Atkinson
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DOI (Published version): 10.1186/1756-0500-3-317
Abstract
To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the L...
| Published in: | BMC Research Notes |
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| Published: |
2010
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| Online Access: |
http://www.biomedcentral.com/1756-0500/3/317/abstract |
| URI: | https://cronfa.swan.ac.uk/Record/cronfa10727 |
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| Abstract: |
To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the LADA patients' versus controls. The average adiponectin level for the LADA patients was 9.96 μg/ml compared to 6.4 μg/ml for Type 2 matched controls and 9.6 μg/ml for non-diabetic controls. Mean difference for the LADA-type 2 comparison was calculated after data was log transformed and showed a difference of 1.58 μg/ml (95%CI: 1.28-1.95, p = 0.0001). There was no significant difference between LADA and non-diabetic controls (p = 0.54). Adiponectin levels are higher among people with LADA compared to those with type 2 diabetes and are equivalent to levels seen in non-diabetic controls. This suggests that risk of complications in LADA, as with type 1 diabetes may be related more to glycaemic control rather than to factors of the metabolic syndrome. |
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| College: |
Faculty of Medicine, Health and Life Sciences |
| Start Page: |
317 |