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DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation

Jennifer Niven, Salih Kucuk Orcid Logo, Atrayee Gope, Michelangelo Certo Orcid Logo, Fearon C Cassidy Orcid Logo, Ainhoa Arana Echarri, Sadaf Ali Orcid Logo, Efthymios Ladoukakis Orcid Logo, Sofia Vidali Orcid Logo, Chiara Macchi, Sayeda S Amir, Ronan Bergin Orcid Logo, Sophie Davies Orcid Logo, Oliver J Perkin Orcid Logo, Joanne Smith, Danilo Cucchi, Helen Heneghan, Susanne Wijesinghe, Benjamin Jenkins, Shanat Baig Orcid Logo, Christopher Mahony Orcid Logo, Chiamaka Chidomere Orcid Logo, Sovan Sarkar, Anna Nicolaou Orcid Logo, Jorge Caamaño Orcid Logo, Adam Croft, Edward Davies, Dylan Thompson, Donal O’Shea, Simon W Jones Orcid Logo, Niharika A Duggal, Massimiliano Ruscica Orcid Logo, Maria Makarova, Nick Jones Orcid Logo, Gabriela Da Silva Xavier Orcid Logo, Tarekegn Geberhiwot, James E Turner, Andrew E Hogan Orcid Logo, Belinda Nedjai, Claudio Mauro Orcid Logo

EMBO Reports

Swansea University Authors: Benjamin Jenkins, Nick Jones Orcid Logo

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Published in: EMBO Reports
ISSN: 1469-3178
Published: Springer Science and Business Media LLC
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URI: https://cronfa.swan.ac.uk/Record/cronfa71815
first_indexed 2026-04-28T08:35:40Z
last_indexed 2026-04-29T05:27:50Z
id cronfa71815
recordtype SURis
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Biomedical Science</level></path><authors><author><firstname>Jennifer</firstname><surname>Niven</surname><order>1</order></author><author><firstname>Salih</firstname><surname>Kucuk</surname><orcid>0000-0002-0939-8508</orcid><order>2</order></author><author><firstname>Atrayee</firstname><surname>Gope</surname><order>3</order></author><author><firstname>Michelangelo</firstname><surname>Certo</surname><orcid>0000-0002-5568-3465</orcid><order>4</order></author><author><firstname>Fearon C</firstname><surname>Cassidy</surname><orcid>0000-0003-2577-9519</orcid><order>5</order></author><author><firstname>Ainhoa Arana</firstname><surname>Echarri</surname><order>6</order></author><author><firstname>Sadaf</firstname><surname>Ali</surname><orcid>0000-0001-6768-5495</orcid><order>7</order></author><author><firstname>Efthymios</firstname><surname>Ladoukakis</surname><orcid>0000-0002-4807-1292</orcid><order>8</order></author><author><firstname>Sofia</firstname><surname>Vidali</surname><orcid>0000-0002-0789-0849</orcid><order>9</order></author><author><firstname>Chiara</firstname><surname>Macchi</surname><order>10</order></author><author><firstname>Sayeda S</firstname><surname>Amir</surname><order>11</order></author><author><firstname>Ronan</firstname><surname>Bergin</surname><orcid>0000-0003-4685-7176</orcid><order>12</order></author><author><firstname>Sophie</firstname><surname>Davies</surname><orcid>0000-0002-6069-1056</orcid><order>13</order></author><author><firstname>Oliver J</firstname><surname>Perkin</surname><orcid>0000-0001-8921-8708</orcid><order>14</order></author><author><firstname>Joanne</firstname><surname>Smith</surname><order>15</order></author><author><firstname>Danilo</firstname><surname>Cucchi</surname><order>16</order></author><author><firstname>Helen</firstname><surname>Heneghan</surname><order>17</order></author><author><firstname>Susanne</firstname><surname>Wijesinghe</surname><order>18</order></author><author><firstname>Benjamin</firstname><surname>Jenkins</surname><orcid/><order>19</order></author><author><firstname>Shanat</firstname><surname>Baig</surname><orcid>0000-0003-1625-6839</orcid><order>20</order></author><author><firstname>Christopher</firstname><surname>Mahony</surname><orcid>0000-0003-4487-2540</orcid><order>21</order></author><author><firstname>Chiamaka</firstname><surname>Chidomere</surname><orcid>0000-0003-3118-4896</orcid><order>22</order></author><author><firstname>Sovan</firstname><surname>Sarkar</surname><order>23</order></author><author><firstname>Anna</firstname><surname>Nicolaou</surname><orcid>0000-0002-1314-413x</orcid><order>24</order></author><author><firstname>Jorge</firstname><surname>Caama&#xF1;o</surname><orcid>0000-0003-3530-7056</orcid><order>25</order></author><author><firstname>Adam</firstname><surname>Croft</surname><order>26</order></author><author><firstname>Edward</firstname><surname>Davies</surname><order>27</order></author><author><firstname>Dylan</firstname><surname>Thompson</surname><order>28</order></author><author><firstname>Donal</firstname><surname>O&#x2019;Shea</surname><order>29</order></author><author><firstname>Simon W</firstname><surname>Jones</surname><orcid>0000-0001-6785-2310</orcid><order>30</order></author><author><firstname>Niharika A</firstname><surname>Duggal</surname><order>31</order></author><author><firstname>Massimiliano</firstname><surname>Ruscica</surname><orcid>0000-0002-0195-7061</orcid><order>32</order></author><author><firstname>Maria</firstname><surname>Makarova</surname><order>33</order></author><author><firstname>Nick</firstname><surname>Jones</surname><orcid>0000-0003-4846-5117</orcid><order>34</order></author><author><firstname>Gabriela Da Silva</firstname><surname>Xavier</surname><orcid>0000-0002-0678-012x</orcid><order>35</order></author><author><firstname>Tarekegn</firstname><surname>Geberhiwot</surname><order>36</order></author><author><firstname>James E</firstname><surname>Turner</surname><order>37</order></author><author><firstname>Andrew E</firstname><surname>Hogan</surname><orcid>0000-0001-5875-230x</orcid><order>38</order></author><author><firstname>Belinda</firstname><surname>Nedjai</surname><order>39</order></author><author><firstname>Claudio</firstname><surname>Mauro</surname><orcid>0000-0002-3736-0099</orcid><order>40</order></author></authors><documents/><OutputDurs/></rfc1807>
spelling 2026-04-28T09:35:38.1705404 v2 71815 2026-04-28 DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation 90f7cfd66781feba615436189178a528 Benjamin Jenkins Benjamin Jenkins true false 0fce0f7ddbdbfeb968f4e2f1e3f86744 0000-0003-4846-5117 Nick Jones Nick Jones true false 2026-04-28 MEDS Journal Article EMBO Reports Springer Science and Business Media LLC 1469-3178 0 0 0 0001-01-01 10.1038/s44319-026-00765-w https://doi.org/10.1038/s44319-026-00765-w COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Another institution paid the OA fee 2026-04-28T09:35:38.1705404 2026-04-28T09:34:58.7823190 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Biomedical Science Jennifer Niven 1 Salih Kucuk 0000-0002-0939-8508 2 Atrayee Gope 3 Michelangelo Certo 0000-0002-5568-3465 4 Fearon C Cassidy 0000-0003-2577-9519 5 Ainhoa Arana Echarri 6 Sadaf Ali 0000-0001-6768-5495 7 Efthymios Ladoukakis 0000-0002-4807-1292 8 Sofia Vidali 0000-0002-0789-0849 9 Chiara Macchi 10 Sayeda S Amir 11 Ronan Bergin 0000-0003-4685-7176 12 Sophie Davies 0000-0002-6069-1056 13 Oliver J Perkin 0000-0001-8921-8708 14 Joanne Smith 15 Danilo Cucchi 16 Helen Heneghan 17 Susanne Wijesinghe 18 Benjamin Jenkins 19 Shanat Baig 0000-0003-1625-6839 20 Christopher Mahony 0000-0003-4487-2540 21 Chiamaka Chidomere 0000-0003-3118-4896 22 Sovan Sarkar 23 Anna Nicolaou 0000-0002-1314-413x 24 Jorge Caamaño 0000-0003-3530-7056 25 Adam Croft 26 Edward Davies 27 Dylan Thompson 28 Donal O’Shea 29 Simon W Jones 0000-0001-6785-2310 30 Niharika A Duggal 31 Massimiliano Ruscica 0000-0002-0195-7061 32 Maria Makarova 33 Nick Jones 0000-0003-4846-5117 34 Gabriela Da Silva Xavier 0000-0002-0678-012x 35 Tarekegn Geberhiwot 36 James E Turner 37 Andrew E Hogan 0000-0001-5875-230x 38 Belinda Nedjai 39 Claudio Mauro 0000-0002-3736-0099 40
title DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
spellingShingle DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
Benjamin Jenkins
Nick Jones
title_short DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
title_full DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
title_fullStr DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
title_full_unstemmed DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
title_sort DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
author_id_str_mv 90f7cfd66781feba615436189178a528
0fce0f7ddbdbfeb968f4e2f1e3f86744
author_id_fullname_str_mv 90f7cfd66781feba615436189178a528_***_Benjamin Jenkins
0fce0f7ddbdbfeb968f4e2f1e3f86744_***_Nick Jones
author Benjamin Jenkins
Nick Jones
author2 Jennifer Niven
Salih Kucuk
Atrayee Gope
Michelangelo Certo
Fearon C Cassidy
Ainhoa Arana Echarri
Sadaf Ali
Efthymios Ladoukakis
Sofia Vidali
Chiara Macchi
Sayeda S Amir
Ronan Bergin
Sophie Davies
Oliver J Perkin
Joanne Smith
Danilo Cucchi
Helen Heneghan
Susanne Wijesinghe
Benjamin Jenkins
Shanat Baig
Christopher Mahony
Chiamaka Chidomere
Sovan Sarkar
Anna Nicolaou
Jorge Caamaño
Adam Croft
Edward Davies
Dylan Thompson
Donal O’Shea
Simon W Jones
Niharika A Duggal
Massimiliano Ruscica
Maria Makarova
Nick Jones
Gabriela Da Silva Xavier
Tarekegn Geberhiwot
James E Turner
Andrew E Hogan
Belinda Nedjai
Claudio Mauro
format Journal article
container_title EMBO Reports
institution Swansea University
issn 1469-3178
doi_str_mv 10.1038/s44319-026-00765-w
publisher Springer Science and Business Media LLC
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Biomedical Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Biomedical Science
url https://doi.org/10.1038/s44319-026-00765-w
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published_date 0001-01-01T07:57:05Z
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