Journal article 115 views 31 downloads
Current mass spectrometry methods for the analysis of 7-ketocholesterol and related sterols
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Mohsen Ali Asgari,
Yuqin Wang
The Journal of Steroid Biochemistry and Molecular Biology, Volume: 259, Start page: 106956
Swansea University Authors:
William Griffiths , Mohsen Ali Asgari, Yuqin Wang
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DOI (Published version): 10.1016/j.jsbmb.2026.106956
Abstract
In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols.
| Published in: | The Journal of Steroid Biochemistry and Molecular Biology |
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| ISSN: | 0960-0760 |
| Published: |
Elsevier BV
2026
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa71464 |
| Abstract: |
In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols. |
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| Keywords: |
Oxysterol; GC-MS; LC-MS; Derivatisation; Autoxidation; Cholesterol |
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
UKRI (MR/Y008057/1, BB/S019588/1) |
| Start Page: |
106956 |