The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review

Alshibani, Abdullah; Warner, Bronwen; Owen, Rhiannon; Mukherjee, Abir; Gilbert, Thomas; Conroy, Simon

doi:10.1136/bmjopen-2022-065499

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The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review

Abdullah Alshibani

, Bronwen Warner, Rhiannon Owen

, Abir Mukherjee, Thomas Gilbert, Simon Conroy

BMJ Open, Volume: 12, Issue: 10, Start page: e065499

Swansea University Author: Rhiannon Owen

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DOI (Published version): 10.1136/bmjopen-2022-065499

Abstract

Introduction Frailty is characterised by vulnerability to adverse health outcomes and increases with age. Many frailty risk scores have been developed. One important example is the Hospital Frailty Risk Score (HFRS) which has the potential to be widely used and automatically calculated which will pr...

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Published in:	BMJ Open
ISSN:	2044-6055 2044-6055
Published:	BMJ 2022
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa71451

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last_indexed	2026-03-07T05:33:04Z
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This systematic review, therefore, seeks to describe the HFRS use since its publication in 2018.Methods and analysis The proposed systematic review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We will include published original peer-reviewed articles, preprints, conference proceedings and letters to the editor reporting primary data where there is an English language abstract available from 1 January 2018 to 30 June 2022. Databases to be searched are MEDLINE, EMBASE and Web of Science. Additional studies from, for example, the reference of the included studies will be identified and assessed for potential inclusion. Two independent reviewers will perform and assess the following: (1) eligibility of the included studies, (2) critical appraisal using the Cochrane Risk of Bias in Non-randomized Studies of Interventions tool, and (3) data extraction using a predefined form. 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spelling	2026-03-06T13:11:52.2579487 v2 71451 2026-02-17 The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review 0d30aa00eef6528f763a1e1589f703ec 0000-0001-5977-376X Rhiannon Owen Rhiannon Owen true false 2026-02-17 MEDS Introduction Frailty is characterised by vulnerability to adverse health outcomes and increases with age. Many frailty risk scores have been developed. One important example is the Hospital Frailty Risk Score (HFRS) which has the potential to be widely used and automatically calculated which will provide accurate assessment of frailty in a time/cost-effective manner. This systematic review, therefore, seeks to describe the HFRS use since its publication in 2018.Methods and analysis The proposed systematic review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We will include published original peer-reviewed articles, preprints, conference proceedings and letters to the editor reporting primary data where there is an English language abstract available from 1 January 2018 to 30 June 2022. Databases to be searched are MEDLINE, EMBASE and Web of Science. Additional studies from, for example, the reference of the included studies will be identified and assessed for potential inclusion. Two independent reviewers will perform and assess the following: (1) eligibility of the included studies, (2) critical appraisal using the Cochrane Risk of Bias in Non-randomized Studies of Interventions tool, and (3) data extraction using a predefined form. Disagreements will be resolved through discussions or by involvement of a third reviewer. It may be possible to undertake a meta-analysis if there are sufficient studies reporting effect measures in homogenous populations and/or settings. Effect sizes will be calculated using meta-analysis methods and expressed as risk ratios or ORs with 95% CIs.Ethics and dissemination No ethical approval is required for this systematic review as it will use secondary data only. The results of the systematic review will be submitted for publication in recognised peer-reviewed journals related to frailty and geriatric care and will be widely disseminated through conferences, congresses, seminars, symposia and scientific meetings. Journal Article BMJ Open 12 10 e065499 BMJ 2044-6055 2044-6055 19 10 2022 2022-10-19 10.1136/bmjopen-2022-065499 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Another institution paid the OA fee King Saud bin Abdulaziz University for Health Sciences (KSAU- HS). 2026-03-06T13:11:52.2579487 2026-02-17T12:40:48.8776967 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Health Data Science Abdullah Alshibani 0000-0002-6709-4721 1 Bronwen Warner 2 Rhiannon Owen 0000-0001-5977-376X 3 Abir Mukherjee 4 Thomas Gilbert 5 Simon Conroy 6 71451__36367__234d70d2c9e94619934ba9f2bd9cdda0.pdf 71451.VoR.pdf 2026-03-06T13:11:00.3011672 Output 265230 application/pdf Version of Record true This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY- NC 4.0) license. true eng http://creativecommons.org/licenses/by-nc/4.0/
title	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
spellingShingle	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review Rhiannon Owen
title_short	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
title_full	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
title_fullStr	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
title_full_unstemmed	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
title_sort	The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review
author_id_str_mv	0d30aa00eef6528f763a1e1589f703ec
author_id_fullname_str_mv	0d30aa00eef6528f763a1e1589f703ec_***_Rhiannon Owen
author	Rhiannon Owen
author2	Abdullah Alshibani Bronwen Warner Rhiannon Owen Abir Mukherjee Thomas Gilbert Simon Conroy
format	Journal article
container_title	BMJ Open
container_volume	12
container_issue	10
container_start_page	e065499
publishDate	2022
institution	Swansea University
issn	2044-6055 2044-6055
doi_str_mv	10.1136/bmjopen-2022-065499
publisher	BMJ
college_str	Faculty of Medicine, Health and Life Sciences
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hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
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hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Health Data Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Health Data Science
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description	Introduction Frailty is characterised by vulnerability to adverse health outcomes and increases with age. Many frailty risk scores have been developed. One important example is the Hospital Frailty Risk Score (HFRS) which has the potential to be widely used and automatically calculated which will provide accurate assessment of frailty in a time/cost-effective manner. This systematic review, therefore, seeks to describe the HFRS use since its publication in 2018.Methods and analysis The proposed systematic review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We will include published original peer-reviewed articles, preprints, conference proceedings and letters to the editor reporting primary data where there is an English language abstract available from 1 January 2018 to 30 June 2022. Databases to be searched are MEDLINE, EMBASE and Web of Science. Additional studies from, for example, the reference of the included studies will be identified and assessed for potential inclusion. Two independent reviewers will perform and assess the following: (1) eligibility of the included studies, (2) critical appraisal using the Cochrane Risk of Bias in Non-randomized Studies of Interventions tool, and (3) data extraction using a predefined form. Disagreements will be resolved through discussions or by involvement of a third reviewer. It may be possible to undertake a meta-analysis if there are sufficient studies reporting effect measures in homogenous populations and/or settings. Effect sizes will be calculated using meta-analysis methods and expressed as risk ratios or ORs with 95% CIs.Ethics and dissemination No ethical approval is required for this systematic review as it will use secondary data only. The results of the systematic review will be submitted for publication in recognised peer-reviewed journals related to frailty and geriatric care and will be widely disseminated through conferences, congresses, seminars, symposia and scientific meetings.
published_date	2022-10-19T05:33:04Z
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The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review

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