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Cardiovascular risk assessment in male and female patients with and without depression: an electronic health record evaluation in Wales
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Richard Summers,
Ann John ,
David P J Osborn,
Keith Lloyd ,
Ashley Akbari ,
Michael Gravenor ,
Julian Halcox
European Journal of Preventive Cardiology, Start page: zwaf178
Swansea University Authors:
Libby Ellins , Richard Summers, Ann John , Keith Lloyd , Ashley Akbari , Michael Gravenor , Julian Halcox
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© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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DOI (Published version): 10.1093/eurjpc/zwaf178
Abstract
Aims: To investigate rates of cardiovascular risk factor assessment (blood pressure, lipid, and QRISK score) in routine clinical practice for primary prevention of cardiovascular disease in patients with and without depression. Methods and results: A retrospective observational cohort study using el...
| Published in: | European Journal of Preventive Cardiology |
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| ISSN: | 2047-4873 2047-4881 |
| Published: |
Oxford University Press (OUP)
2025
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa69153 |
| Abstract: |
Aims: To investigate rates of cardiovascular risk factor assessment (blood pressure, lipid, and QRISK score) in routine clinical practice for primary prevention of cardiovascular disease in patients with and without depression. Methods and results: A retrospective observational cohort study using electronic health record data sources was carried out. Rates of blood pressure measurement, lipid checks, and QRISK documentation in primary care were calculated for non-depressed, and patients prior and subsequent to depression diagnosis. Poisson regression adjusting for age and sex was used to explore associations between depression status and rate of assessment. Differences in rates of assessment by deprivation and location of residence (urban/rural) were also explored. Of 2 290 075 patients, 176 062 had depression diagnosed. Patients with depression had blood pressure and lipid levels checked and QRISK score documented more frequently, after adjustment for sex and age group. Sex differences were noted, with younger females more likely to have blood pressure assessment and males more likely to have lipid levels checked, irrespective of depression status. There were significant three-way interactions between depression ∗ sex ∗ age group for all outcomes, with sex difference in blood pressure assessment highly dependent on age, and sex/depression status difference in lipid assessment most notable in the 60–74 age group. Conclusion:Patients with depression are more likely to have their blood pressure, lipid levels, and QRISK documented than patients without depression. Sex differences in assessment of blood pressure and lipid assessments may also impact on future cardiovascular risk management, providing opportunities for potential improvements in assessment of risk factors. |
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| Keywords: |
Depression, Risk factors, Blood pressure, Lipids, Cardiovascular disease |
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
The study was funded by the British Heart Foundation Project Grant ref. PG/21/10631. |
| Start Page: |
zwaf178 |