Journal article 62 views
Microbiome and epigenetic variation in wild fish with low genetic diversity
Ishrat Z. Anka 
,
Tamsyn Uren Webster ,
Waldir M. Berbel-Filho ,
Matthew Hitchings ,
Benjamin Overland,
Sarah Weller ,
Carlos Garcia De Leaniz ,
Sofia Consuegra del Olmo
,
Tamsyn Uren Webster ,
Waldir M. Berbel-Filho ,
Matthew Hitchings ,
Benjamin Overland,
Sarah Weller ,
Carlos Garcia De Leaniz ,
Sofia Consuegra del Olmo
Nature Communications, Volume: 15, Issue: 1
Swansea University Authors:
Tamsyn Uren Webster , Matthew Hitchings , Carlos Garcia De Leaniz , Sofia Consuegra del Olmo
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1038/s41467-024-49162-8
Abstract
Non-genetic sources of phenotypic variation, such as the epigenome and the microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about the complex interaction between these factors and the genetic diversity of the host, par...
| Published in: | Nature Communications |
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| ISSN: | 2041-1723 |
| Published: |
Springer Science and Business Media LLC
2024
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| Online Access: |
Check full text
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa67975 |
| first_indexed |
2024-10-14T08:48:27Z |
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| last_indexed |
2025-01-09T20:32:16Z |
| id |
cronfa67975 |
| recordtype |
SURis |
| fullrecord |
<?xml version="1.0"?><rfc1807><datestamp>2024-12-20T14:24:55.6384163</datestamp><bib-version>v2</bib-version><id>67975</id><entry>2024-10-14</entry><title>Microbiome and epigenetic variation in wild fish with low genetic diversity</title><swanseaauthors><author><sid>3ea91c154926c86f89ea6a761122ecf6</sid><ORCID>0000-0002-0072-9745</ORCID><firstname>Tamsyn</firstname><surname>Uren Webster</surname><name>Tamsyn Uren Webster</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>be98847c72c14a731c4a6b7bc02b3bcf</sid><ORCID>0000-0002-5527-4709</ORCID><firstname>Matthew</firstname><surname>Hitchings</surname><name>Matthew Hitchings</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>1c70acd0fd64edb0856b7cf34393ab02</sid><ORCID>0000-0003-1650-2729</ORCID><firstname>Carlos</firstname><surname>Garcia De Leaniz</surname><name>Carlos Garcia De Leaniz</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>241f2810ab8f56be53ca8af23e384c6e</sid><ORCID>0000-0003-4403-2509</ORCID><firstname>Sofia</firstname><surname>Consuegra del Olmo</surname><name>Sofia Consuegra del Olmo</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2024-10-14</date><deptcode>BGPS</deptcode><abstract>Non-genetic sources of phenotypic variation, such as the epigenome and the microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about the complex interaction between these factors and the genetic diversity of the host, particularly in wild populations. Here, we examine the skin microbiome composition of two closely-related mangrove killifish species with different mating systems (self-fertilising and outcrossing) under sympatric and allopatric conditions. This allows us to partition the influence of the genotype and the environment on their microbiome and (previously described) epigenetic profiles. We find the diversity and community composition of the skin microbiome are strongly shaped by the environment and, to a lesser extent, by species-specific influences. Heterozygosity and microbiome alpha diversity, but not epigenetic variation, are associated with the fluctuating asymmetry of traits related to performance (vision) and behaviour (aggression). Our study identifies that a proportion of the epigenetic diversity and microbiome differentiation is unrelated to genetic variation, and we find evidence for an associative relationship between microbiome and epigenetic diversity in these wild populations. This suggests that both mechanisms could potentially contribute to variation in species with low genetic diversity.</abstract><type>Journal Article</type><journal>Nature Communications</journal><volume>15</volume><journalNumber>1</journalNumber><paginationStart/><paginationEnd/><publisher>Springer Science and Business Media LLC</publisher><placeOfPublication/><isbnPrint/><isbnElectronic/><issnPrint/><issnElectronic>2041-1723</issnElectronic><keywords/><publishedDay>3</publishedDay><publishedMonth>6</publishedMonth><publishedYear>2024</publishedYear><publishedDate>2024-06-03</publishedDate><doi>10.1038/s41467-024-49162-8</doi><url/><notes/><college>COLLEGE NANME</college><department>Biosciences Geography and Physics School</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>BGPS</DepartmentCode><institution>Swansea University</institution><apcterm/><funders>We are grateful to ICMbio for providing help with accommodation and facilities and to Sergio Lima, Helder M.V. Espírito-Santo, Mateus Lira for support during sample collections. Fieldwork was supported by the National Geographic/Waitt program [W461-16] to SC and by a scholarship from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) to WMB-F. I.A. was supported by a Commonwealth PhD Scholarship (BDCS-2020-41). S.C. was partially funded by a Royal Society Industry Fellowship Ref: IF\R1\231030.</funders><projectreference/><lastEdited>2024-12-20T14:24:55.6384163</lastEdited><Created>2024-10-14T09:41:51.7453246</Created><path><level id="1">Faculty of Science and Engineering</level><level id="2">School of Biosciences, Geography and Physics - Biosciences</level></path><authors><author><firstname>Ishrat Z.</firstname><surname>Anka</surname><orcid>0000-0003-3533-0344</orcid><order>1</order></author><author><firstname>Tamsyn</firstname><surname>Uren Webster</surname><orcid>0000-0002-0072-9745</orcid><order>2</order></author><author><firstname>Waldir M.</firstname><surname>Berbel-Filho</surname><orcid>0000-0001-6991-4685</orcid><order>3</order></author><author><firstname>Matthew</firstname><surname>Hitchings</surname><orcid>0000-0002-5527-4709</orcid><order>4</order></author><author><firstname>Benjamin</firstname><surname>Overland</surname><order>5</order></author><author><firstname>Sarah</firstname><surname>Weller</surname><orcid>0009-0004-4507-1344</orcid><order>6</order></author><author><firstname>Carlos</firstname><surname>Garcia De Leaniz</surname><orcid>0000-0003-1650-2729</orcid><order>7</order></author><author><firstname>Sofia</firstname><surname>Consuegra del Olmo</surname><orcid>0000-0003-4403-2509</orcid><order>8</order></author></authors><documents/><OutputDurs/></rfc1807> |
| spelling |
2024-12-20T14:24:55.6384163 v2 67975 2024-10-14 Microbiome and epigenetic variation in wild fish with low genetic diversity 3ea91c154926c86f89ea6a761122ecf6 0000-0002-0072-9745 Tamsyn Uren Webster Tamsyn Uren Webster true false be98847c72c14a731c4a6b7bc02b3bcf 0000-0002-5527-4709 Matthew Hitchings Matthew Hitchings true false 1c70acd0fd64edb0856b7cf34393ab02 0000-0003-1650-2729 Carlos Garcia De Leaniz Carlos Garcia De Leaniz true false 241f2810ab8f56be53ca8af23e384c6e 0000-0003-4403-2509 Sofia Consuegra del Olmo Sofia Consuegra del Olmo true false 2024-10-14 BGPS Non-genetic sources of phenotypic variation, such as the epigenome and the microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about the complex interaction between these factors and the genetic diversity of the host, particularly in wild populations. Here, we examine the skin microbiome composition of two closely-related mangrove killifish species with different mating systems (self-fertilising and outcrossing) under sympatric and allopatric conditions. This allows us to partition the influence of the genotype and the environment on their microbiome and (previously described) epigenetic profiles. We find the diversity and community composition of the skin microbiome are strongly shaped by the environment and, to a lesser extent, by species-specific influences. Heterozygosity and microbiome alpha diversity, but not epigenetic variation, are associated with the fluctuating asymmetry of traits related to performance (vision) and behaviour (aggression). Our study identifies that a proportion of the epigenetic diversity and microbiome differentiation is unrelated to genetic variation, and we find evidence for an associative relationship between microbiome and epigenetic diversity in these wild populations. This suggests that both mechanisms could potentially contribute to variation in species with low genetic diversity. Journal Article Nature Communications 15 1 Springer Science and Business Media LLC 2041-1723 3 6 2024 2024-06-03 10.1038/s41467-024-49162-8 COLLEGE NANME Biosciences Geography and Physics School COLLEGE CODE BGPS Swansea University We are grateful to ICMbio for providing help with accommodation and facilities and to Sergio Lima, Helder M.V. Espírito-Santo, Mateus Lira for support during sample collections. Fieldwork was supported by the National Geographic/Waitt program [W461-16] to SC and by a scholarship from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) to WMB-F. I.A. was supported by a Commonwealth PhD Scholarship (BDCS-2020-41). S.C. was partially funded by a Royal Society Industry Fellowship Ref: IF\R1\231030. 2024-12-20T14:24:55.6384163 2024-10-14T09:41:51.7453246 Faculty of Science and Engineering School of Biosciences, Geography and Physics - Biosciences Ishrat Z. Anka 0000-0003-3533-0344 1 Tamsyn Uren Webster 0000-0002-0072-9745 2 Waldir M. Berbel-Filho 0000-0001-6991-4685 3 Matthew Hitchings 0000-0002-5527-4709 4 Benjamin Overland 5 Sarah Weller 0009-0004-4507-1344 6 Carlos Garcia De Leaniz 0000-0003-1650-2729 7 Sofia Consuegra del Olmo 0000-0003-4403-2509 8 |
| title |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| spellingShingle |
Microbiome and epigenetic variation in wild fish with low genetic diversity Tamsyn Uren Webster Matthew Hitchings Carlos Garcia De Leaniz Sofia Consuegra del Olmo |
| title_short |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| title_full |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| title_fullStr |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| title_full_unstemmed |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| title_sort |
Microbiome and epigenetic variation in wild fish with low genetic diversity |
| author_id_str_mv |
3ea91c154926c86f89ea6a761122ecf6 be98847c72c14a731c4a6b7bc02b3bcf 1c70acd0fd64edb0856b7cf34393ab02 241f2810ab8f56be53ca8af23e384c6e |
| author_id_fullname_str_mv |
3ea91c154926c86f89ea6a761122ecf6_***_Tamsyn Uren Webster be98847c72c14a731c4a6b7bc02b3bcf_***_Matthew Hitchings 1c70acd0fd64edb0856b7cf34393ab02_***_Carlos Garcia De Leaniz 241f2810ab8f56be53ca8af23e384c6e_***_Sofia Consuegra del Olmo |
| author |
Tamsyn Uren Webster Matthew Hitchings Carlos Garcia De Leaniz Sofia Consuegra del Olmo |
| author2 |
Ishrat Z. Anka Tamsyn Uren Webster Waldir M. Berbel-Filho Matthew Hitchings Benjamin Overland Sarah Weller Carlos Garcia De Leaniz Sofia Consuegra del Olmo |
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Journal article |
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Nature Communications |
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15 |
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1 |
| publishDate |
2024 |
| institution |
Swansea University |
| issn |
2041-1723 |
| doi_str_mv |
10.1038/s41467-024-49162-8 |
| publisher |
Springer Science and Business Media LLC |
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Faculty of Science and Engineering |
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facultyofscienceandengineering |
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Faculty of Science and Engineering |
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facultyofscienceandengineering |
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Faculty of Science and Engineering |
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School of Biosciences, Geography and Physics - Biosciences{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Biosciences, Geography and Physics - Biosciences |
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| description |
Non-genetic sources of phenotypic variation, such as the epigenome and the microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about the complex interaction between these factors and the genetic diversity of the host, particularly in wild populations. Here, we examine the skin microbiome composition of two closely-related mangrove killifish species with different mating systems (self-fertilising and outcrossing) under sympatric and allopatric conditions. This allows us to partition the influence of the genotype and the environment on their microbiome and (previously described) epigenetic profiles. We find the diversity and community composition of the skin microbiome are strongly shaped by the environment and, to a lesser extent, by species-specific influences. Heterozygosity and microbiome alpha diversity, but not epigenetic variation, are associated with the fluctuating asymmetry of traits related to performance (vision) and behaviour (aggression). Our study identifies that a proportion of the epigenetic diversity and microbiome differentiation is unrelated to genetic variation, and we find evidence for an associative relationship between microbiome and epigenetic diversity in these wild populations. This suggests that both mechanisms could potentially contribute to variation in species with low genetic diversity. |
| published_date |
2024-06-03T14:37:34Z |
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1821326028312674304 |
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11.564073 |