Journal article 94 views
Interventions to support patients with sharing genetic test results with at-risk relatives: a synthesis without meta-analysis (SWiM)
,
Becky Band ,
Anneke M. Lucassen
European Journal of Human Genetics, Volume: 31, Issue: 9, Pages: 988 - 1002
Swansea University Author:
Becky Band
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1038/s41431-023-01400-1
Abstract
Whilst the finding of heritable susceptibility to disease was once relatively rare, mainstreaming of genetic testing has resulted in a steady increase. Patients are often encouraged to share their genetic test results with relevant relatives, but relatives may not receive this information, leaving t...
| Published in: | European Journal of Human Genetics |
|---|---|
| ISSN: | 1018-4813 1476-5438 |
| Published: |
Springer Science and Business Media LLC
2023
|
| Online Access: |
Check full text
|
| URI: | https://cronfa.swan.ac.uk/Record/cronfa67967 |
| Abstract: |
Whilst the finding of heritable susceptibility to disease was once relatively rare, mainstreaming of genetic testing has resulted in a steady increase. Patients are often encouraged to share their genetic test results with relevant relatives, but relatives may not receive this information, leaving them without knowledge of their own risk. Therefore, strategies to help communicate such information are important. This review aimed to explore the efficacy of existing interventions to improve the sharing of genetic test results. A synthesis without meta-analysis design was used. A systematic search of Medline, CINAHL, PsychINFO, and AMED was conducted, and five studies were identified worldwide. Data were extracted for each study regarding study aim, participant characteristics, condition, intervention details, comparison, study duration, outcome measures, theory and behaviour change techniques used. Limited efficacy and application of theory was found. Knowledge, motivation and self-efficacy were not increased in any intervention. No gender differences in communication behaviour were encountered in interventions that recruited men and women. Two studies reported an evaluation of acceptability, which showed that the interventions were well received by patients and health professionals. No study reported the involvement of the target population in any phase of intervention development. Given the lack of health psychology-informed interventions in this area of clinical genetics, we recommend genetic health professionals, health psychologists and patients collaborate on all stages of future interventions that involve the cascading of genetic health information within families. We also provide guidance regarding use of theory and intervention elements for future intervention development. |
|---|---|
| College: |
Faculty of Medicine, Health and Life Sciences |
| Funders: |
Health Education England Genomics Education Programme; National Institute for Health Research Biomedical Research Centre Southampton. This work was also supported by funding from a Wellcome Trust collaborative award |
| Issue: |
9 |
| Start Page: |
988 |
| End Page: |
1002 |