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Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse / ROMESSA MAHMOOD

Swansea University Author: ROMESSA MAHMOOD

Abstract

To replace, reduce and refine using vertebrates in pharmacological research, invertebrate in vivo models are required to continue investigating pharmacology in whole animal systems. This study presents the freshwater oligochaete worm Lumbriculus variegatus as a novel in vivo invertebrate model to st...

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Published: Swansea, Wales, UK 2024
Institution: Swansea University
Degree level: Master of Research
Degree name: MSc by Research
Supervisor: Wallace, Lisa ; Davies, Nia ; Seeley, Aidan
URI: https://cronfa.swan.ac.uk/Record/cronfa66584
first_indexed 2024-06-03T14:37:52Z
last_indexed 2024-11-25T14:18:28Z
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recordtype RisThesis
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spelling 2024-06-03T16:09:19.1612614 v2 66584 2024-06-03 Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse ef1f983edbeb76c80ca1b3374f89b8b3 ROMESSA MAHMOOD ROMESSA MAHMOOD true false 2024-06-03 To replace, reduce and refine using vertebrates in pharmacological research, invertebrate in vivo models are required to continue investigating pharmacology in whole animal systems. This study presents the freshwater oligochaete worm Lumbriculus variegatus as a novel in vivo invertebrate model to study the behavioural and physiological effects of ethanol and nicotine, two widely used substances of abuse. E-Thesis Swansea, Wales, UK Invertebrates, models, animals, ethanol, nicotine, oligochaetes, substances of abuse 29 5 2024 2024-05-29 COLLEGE NANME COLLEGE CODE Swansea University Wallace, Lisa ; Davies, Nia ; Seeley, Aidan Master of Research MSc by Research 2024-06-03T16:09:19.1612614 2024-06-03T15:30:26.2298203 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Biomedical Science ROMESSA MAHMOOD 1 66584__30535__b9feb48760594096be5dec2c67a1f0ab.pdf Mahmood_Romessa_MSc_Research_Thesis_Final_Redacted_Signature.pdf 2024-06-03T15:46:40.0036664 Output 20718247 application/pdf E-Thesis – open access true Copyright: The Author, Romessa Mahmood, 2024. true eng
title Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
spellingShingle Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
ROMESSA MAHMOOD
title_short Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
title_full Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
title_fullStr Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
title_full_unstemmed Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
title_sort Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse
author_id_str_mv ef1f983edbeb76c80ca1b3374f89b8b3
author_id_fullname_str_mv ef1f983edbeb76c80ca1b3374f89b8b3_***_ROMESSA MAHMOOD
author ROMESSA MAHMOOD
author2 ROMESSA MAHMOOD
format E-Thesis
publishDate 2024
institution Swansea University
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Biomedical Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Biomedical Science
document_store_str 1
active_str 0
description To replace, reduce and refine using vertebrates in pharmacological research, invertebrate in vivo models are required to continue investigating pharmacology in whole animal systems. This study presents the freshwater oligochaete worm Lumbriculus variegatus as a novel in vivo invertebrate model to study the behavioural and physiological effects of ethanol and nicotine, two widely used substances of abuse.
published_date 2024-05-29T14:33:47Z
_version_ 1821325789414555648
score 11.048042

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