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Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications

Lue Wang, Waye Zhang Orcid Logo

Sensors and Actuators Reports, Volume: 5, Start page: 100153

Swansea University Author: Waye Zhang Orcid Logo

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DOI (Published version): 10.1016/j.snr.2023.100153

Abstract

Molecularly imprinted polymer (MIP)-based electrochemical sensors have received growing attention over past decades owing to its robust nature, simple electrochemical control for template removal and cavity regeneration, and go-as-you-please cavity designs into various geometries specific to target...

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Published in: Sensors and Actuators Reports
ISSN: 2666-0539
Published: Elsevier BV 2023
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URI: https://cronfa.swan.ac.uk/Record/cronfa63361
first_indexed 2023-05-06T10:55:41Z
last_indexed 2024-11-15T18:01:26Z
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spelling 2023-06-09T14:05:07.9478983 v2 63361 2023-05-06 Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications 3ddabbb54b2cfa2ea10f590ea7da6520 0000-0003-3129-2918 Waye Zhang Waye Zhang true false 2023-05-06 EAAS Molecularly imprinted polymer (MIP)-based electrochemical sensors have received growing attention over past decades owing to its robust nature, simple electrochemical control for template removal and cavity regeneration, and go-as-you-please cavity designs into various geometries specific to target analytes. The strength of MIP scheme, in combination with the advantages of electrochemical sensing techniques such as operation simplicity, rapid response, and high sensitivity, provide a synergistic effort to form a highly effective sensing platform suitable for an extremely wide range of interest. In this Review, the introduction of MIP and the comparison between electrochemical sensing methods and other detection strategies are briefly discussed. Then, a broad range of analytes determined using MIP-based electrochemical sensors are listed and critically reviewed, mainly focusing on the applied electrochemical technique, presented linear range along with limit of detection (LOD), biological fluid used in real testing, and pretreatment for real sample. Other sensor performances like selectivity towards analyte, signal repeatability, sensor-to-sensor reproducibility, and stability, are carefully compared with other reported papers. MIP sensors fabricated via the nanoMIP technology, and the ones integrated with portable analyzers, are given in more details as good results are always observed in such instances. Finally, a conclusionregarding recent advances on MIP-based electrochemical sensors is presented, followed by current issues and future development depicted at the last section of the Review. Journal Article Sensors and Actuators Reports 5 100153 Elsevier BV 2666-0539 Molecularly imprinted polymer (MIP), Electrochemical, Sensor, Health application, Clinical 1 6 2023 2023-06-01 10.1016/j.snr.2023.100153 http://dx.doi.org/10.1016/j.snr.2023.100153 COLLEGE NANME Engineering and Applied Sciences School COLLEGE CODE EAAS Swansea University SU Library paid the OA fee (TA Institutional Deal) Mr Matthew Pagett would like to acknowledge the financial support from EPSRC DTP program for his PhD scholarship (Ep/R51312x/1). 2023-06-09T14:05:07.9478983 2023-05-06T11:46:26.7079783 Faculty of Science and Engineering School of Engineering and Applied Sciences - Chemical Engineering Lue Wang 1 Waye Zhang 0000-0003-3129-2918 2 63361__27422__af7943cc1c7c433584b69bab0096ef55.pdf 633.61VOR.pdf 2023-05-10T20:45:14.2593211 Output 10645457 application/pdf Version of Record true This is an open access article under the CC BY license. true eng http://creativecommons.org/licenses/by/4.0/
title Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
spellingShingle Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
Waye Zhang
title_short Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
title_full Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
title_fullStr Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
title_full_unstemmed Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
title_sort Molecularly imprinted polymer (MIP) based electrochemical sensors and their recent advances in health applications
author_id_str_mv 3ddabbb54b2cfa2ea10f590ea7da6520
author_id_fullname_str_mv 3ddabbb54b2cfa2ea10f590ea7da6520_***_Waye Zhang
author Waye Zhang
author2 Lue Wang
Waye Zhang
format Journal article
container_title Sensors and Actuators Reports
container_volume 5
container_start_page 100153
publishDate 2023
institution Swansea University
issn 2666-0539
doi_str_mv 10.1016/j.snr.2023.100153
publisher Elsevier BV
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Chemical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Chemical Engineering
url http://dx.doi.org/10.1016/j.snr.2023.100153
document_store_str 1
active_str 0
description Molecularly imprinted polymer (MIP)-based electrochemical sensors have received growing attention over past decades owing to its robust nature, simple electrochemical control for template removal and cavity regeneration, and go-as-you-please cavity designs into various geometries specific to target analytes. The strength of MIP scheme, in combination with the advantages of electrochemical sensing techniques such as operation simplicity, rapid response, and high sensitivity, provide a synergistic effort to form a highly effective sensing platform suitable for an extremely wide range of interest. In this Review, the introduction of MIP and the comparison between electrochemical sensing methods and other detection strategies are briefly discussed. Then, a broad range of analytes determined using MIP-based electrochemical sensors are listed and critically reviewed, mainly focusing on the applied electrochemical technique, presented linear range along with limit of detection (LOD), biological fluid used in real testing, and pretreatment for real sample. Other sensor performances like selectivity towards analyte, signal repeatability, sensor-to-sensor reproducibility, and stability, are carefully compared with other reported papers. MIP sensors fabricated via the nanoMIP technology, and the ones integrated with portable analyzers, are given in more details as good results are always observed in such instances. Finally, a conclusionregarding recent advances on MIP-based electrochemical sensors is presented, followed by current issues and future development depicted at the last section of the Review.
published_date 2023-06-01T05:25:58Z
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score 11.29607

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