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Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial

Olivia McCarthy, Merete Bechmann Christensen, Kasper Birch Kristensen, Signe Schmidt Orcid Logo, Ajenthen G. Ranjan, Steve Bain Orcid Logo, Richard Bracken Orcid Logo, Kirsten Nørgaard

Diabetes Technology & Therapeutics, Volume: 25, Issue: 4, Pages: 287 - 292

Swansea University Authors: Olivia McCarthy, Steve Bain Orcid Logo, Richard Bracken Orcid Logo

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DOI (Published version): 10.1089/dia.2022.0542

Abstract

In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management gui...

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Published in: Diabetes Technology & Therapeutics
ISSN: 1520-9156 1557-8593
Published: Mary Ann Liebert Inc 2023
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URI: https://cronfa.swan.ac.uk/Record/cronfa63164
Abstract: In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management guidelines for performing exercise were applied. Plasma glucose concentrations measured over a 3-h monitoring period were stratified into time below range (TBR, <3.9 mmol/L), time in range (TIR, 3.9–10.0 mmol/L), and time above range (TAR, >10.0 mmol/L).Overall, TBR (UP: 11 ± 21 vs. AID: 3% ± 10%, P = 0.413), TIR (UP: 53 ± 27 vs. AID: 66% ± 39%, P = 0.320), and TAR (UP: 37 ± 34 vs. AID: 31% ± 41%, P = 0.604) were similar between arms. A proportionately low number of people experienced exercise-induced hypoglycemia (UP: n = 2 vs. AID: n = 1, P = 1.00).In conclusion, switching to AID therapy did not alter patterns of glycemia around sustained moderate-intensity exercise in adults with T1D.
College: Faculty of Science and Engineering
Issue: 4
Start Page: 287
End Page: 292