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Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial

Olivia M. McCarthy Orcid Logo, Merete Bechmann Christensen, Kasper Birch Kristensen, Signe Schmidt Orcid Logo, Ajenthen G. Ranjan, Stephen C. Bain, Richard Bracken Orcid Logo, Kirsten Nørgaard

Diabetes Technology & Therapeutics, Volume: 25, Issue: 4, Pages: 287 - 292

Swansea University Author: Richard Bracken Orcid Logo

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DOI (Published version): 10.1089/dia.2022.0542

Abstract

In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management gui...

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Published in: Diabetes Technology & Therapeutics
ISSN: 1520-9156 1557-8593
Published: Mary Ann Liebert Inc 2023
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URI: https://cronfa.swan.ac.uk/Record/cronfa63164
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Abstract: In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management guidelines for performing exercise were applied. Plasma glucose concentrations measured over a 3-h monitoring period were stratified into time below range (TBR, <3.9 mmol/L), time in range (TIR, 3.9–10.0 mmol/L), and time above range (TAR, >10.0 mmol/L).Overall, TBR (UP: 11 ± 21 vs. AID: 3% ± 10%, P = 0.413), TIR (UP: 53 ± 27 vs. AID: 66% ± 39%, P = 0.320), and TAR (UP: 37 ± 34 vs. AID: 31% ± 41%, P = 0.604) were similar between arms. A proportionately low number of people experienced exercise-induced hypoglycemia (UP: n = 2 vs. AID: n = 1, P = 1.00).In conclusion, switching to AID therapy did not alter patterns of glycemia around sustained moderate-intensity exercise in adults with T1D.
College: Faculty of Science and Engineering
Issue: 4
Start Page: 287
End Page: 292

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