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A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta

Betsy Dayana Marcela Chaparro Rico Orcid Logo, Betsy D. M. Chaparro-Rico Orcid Logo, Fabio Sebastiano, Daniele Cafolla Orcid Logo

Machines, Volume: 8, Issue: 4, Start page: 81

Swansea University Authors: Betsy Dayana Marcela Chaparro Rico Orcid Logo, Daniele Cafolla Orcid Logo

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DOI (Published version): 10.3390/machines8040081

Abstract

Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelop...

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Published in: Machines
ISSN: 2075-1702
Published: MDPI AG 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa62498
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last_indexed 2023-03-02T04:17:37Z
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spelling 2023-03-01T15:10:27.0345073 v2 62498 2023-02-03 A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta fab062f51ecae36a295bd5c53e03fef5 0000-0002-6874-2508 Betsy Dayana Marcela Chaparro Rico Betsy Dayana Marcela Chaparro Rico true false ac4feae4da44720e216ab2e0359e4ddb 0000-0002-5602-1519 Daniele Cafolla Daniele Cafolla true false 2023-02-03 MACS Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelope, and pair-operated ultrasonic sensors for restenosis monitoring through flow velocity. Aside from continuous monitoring of restenosis post-implantation, it is also important to evaluate whether the stent design itself causes complications such as restenosis or thrombosis. Therefore, computational fluid dynamic (CFD) analysis before and after stent implantation were carried out as well as finite element analysis (FEA). The proposed smart stent was put in the descending thoracic section of a virtually reconstructed aorta that comes from a computed tomography (CT) scan. Blood flow velocity showed that after stent implantation, there is not liquid retention or vortex generation. In addition, blood pressures after stent implantation were within the normal blood pressure values. The stress and the factor of safety (FOS) analysis showed that the stress values reached by the stent are very far from the yield strength limit of the materials and that the stent is stiff enough to support the applied loads exported from the CFD results. Journal Article Machines 8 4 81 MDPI AG 2075-1702 implantable devices; biocompatible; smart stent; restenosis; stent simulation 24 11 2020 2020-11-24 10.3390/machines8040081 COLLEGE NANME Mathematics and Computer Science School COLLEGE CODE MACS Swansea University 2023-03-01T15:10:27.0345073 2023-02-03T14:17:28.7660727 Faculty of Science and Engineering School of Mathematics and Computer Science - Computer Science Betsy Dayana Marcela Chaparro Rico 0000-0002-6874-2508 1 Betsy D. M. Chaparro-Rico 0000-0002-6874-2508 2 Fabio Sebastiano 3 Daniele Cafolla 0000-0002-5602-1519 4 62498__26715__821a102642c64ed78692873345aa6c26.pdf 62498_VoR.pdf 2023-03-01T15:09:06.2334030 Output 4141160 application/pdf Version of Record true © 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license true eng http://creativecommons.org/licenses/by/4.0/
title A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
spellingShingle A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
Betsy Dayana Marcela Chaparro Rico
Daniele Cafolla
title_short A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_full A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_fullStr A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_full_unstemmed A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_sort A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
author_id_str_mv fab062f51ecae36a295bd5c53e03fef5
ac4feae4da44720e216ab2e0359e4ddb
author_id_fullname_str_mv fab062f51ecae36a295bd5c53e03fef5_***_Betsy Dayana Marcela Chaparro Rico
ac4feae4da44720e216ab2e0359e4ddb_***_Daniele Cafolla
author Betsy Dayana Marcela Chaparro Rico
Daniele Cafolla
author2 Betsy Dayana Marcela Chaparro Rico
Betsy D. M. Chaparro-Rico
Fabio Sebastiano
Daniele Cafolla
format Journal article
container_title Machines
container_volume 8
container_issue 4
container_start_page 81
publishDate 2020
institution Swansea University
issn 2075-1702
doi_str_mv 10.3390/machines8040081
publisher MDPI AG
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Mathematics and Computer Science - Computer Science{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Mathematics and Computer Science - Computer Science
document_store_str 1
active_str 0
description Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelope, and pair-operated ultrasonic sensors for restenosis monitoring through flow velocity. Aside from continuous monitoring of restenosis post-implantation, it is also important to evaluate whether the stent design itself causes complications such as restenosis or thrombosis. Therefore, computational fluid dynamic (CFD) analysis before and after stent implantation were carried out as well as finite element analysis (FEA). The proposed smart stent was put in the descending thoracic section of a virtually reconstructed aorta that comes from a computed tomography (CT) scan. Blood flow velocity showed that after stent implantation, there is not liquid retention or vortex generation. In addition, blood pressures after stent implantation were within the normal blood pressure values. The stress and the factor of safety (FOS) analysis showed that the stress values reached by the stent are very far from the yield strength limit of the materials and that the stent is stiff enough to support the applied loads exported from the CFD results.
published_date 2020-11-24T20:19:19Z
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