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Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents

Arshid Numan, Prabh Simran Singh, Aftab Alam, Mohammad Khalid, Lijie Li Orcid Logo, Sima Singh Orcid Logo

ACS Omega, Volume: 7, Issue: 31, Pages: 27079 - 27089

Swansea University Author: Lijie Li Orcid Logo

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DOI (Published version): 10.1021/acsomega.2c03645

Abstract

Efficient and simple detection of chemical warfare agents (CWAs) is an essential step in minimizing the potentially lethal consequences of chemical weapons. CWAs are a family of organic chemicals that are used as chemical weapons because of their enormous severity and lethal effects when faced with...

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Published in: ACS Omega
ISSN: 2470-1343 2470-1343
Published: American Chemical Society (ACS) 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa61663
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spelling 2022-11-11T14:34:22.8334128 v2 61663 2022-10-25 Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents ed2c658b77679a28e4c1dcf95af06bd6 0000-0003-4630-7692 Lijie Li Lijie Li true false 2022-10-25 EEEG Efficient and simple detection of chemical warfare agents (CWAs) is an essential step in minimizing the potentially lethal consequences of chemical weapons. CWAs are a family of organic chemicals that are used as chemical weapons because of their enormous severity and lethal effects when faced with unforeseen challenges. To stop the spread of CWAs, it is critical to develop a platform that detects them in a sensitive, timely, selective, and minimally invasive manner. Rapid advances in the demand for on-site sensors, metal nanoparticles, and biomarker identification for CWAs have made it possible to use fluorescence as a precise real-time and point-of-care (POCT) testing technique. For POCT-based applications, the new capabilities of micro- and nanomotors offer enormous prospects. In recent decades, significant progress has been made in the design of fluorescent sensors and the further development of noble metal nanoparticles for the detection of organophosphorus CWAs, as described in this review. Through this work, recent attempts to fabricate sensors that can detect organophosphorus CWAs through changes in their fluorescence properties have been summarized. Finally, an integrated outlook on how noble metal nanoparticles could be used to develop smart sensors for organophosphorus CWAs that communicate with and control electronic devices to monitor and improve the health of individuals. Journal Article ACS Omega 7 31 27079 27089 American Chemical Society (ACS) 2470-1343 2470-1343 9 8 2022 2022-08-09 10.1021/acsomega.2c03645 COLLEGE NANME Electronic and Electrical Engineering COLLEGE CODE EEEG Swansea University 2022-11-11T14:34:22.8334128 2022-10-25T18:19:12.6438861 Faculty of Science and Engineering School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Electronic and Electrical Engineering Arshid Numan 1 Prabh Simran Singh 2 Aftab Alam 3 Mohammad Khalid 4 Lijie Li 0000-0003-4630-7692 5 Sima Singh 0000-0002-5277-3430 6 61663__25587__508cac790b284a03af0900724d51cd3c.pdf acsomega.2c03645.pdf 2022-10-25T18:20:07.4389503 Output 5636197 application/pdf Version of Record true Released under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License true eng https://creativecommons.org/licenses/by-nc-nd/4.0/
title Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
spellingShingle Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
Lijie Li
title_short Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
title_full Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
title_fullStr Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
title_full_unstemmed Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
title_sort Advances in Noble-Metal Nanoparticle-Based Fluorescence Detection of Organophosphorus Chemical Warfare Agents
author_id_str_mv ed2c658b77679a28e4c1dcf95af06bd6
author_id_fullname_str_mv ed2c658b77679a28e4c1dcf95af06bd6_***_Lijie Li
author Lijie Li
author2 Arshid Numan
Prabh Simran Singh
Aftab Alam
Mohammad Khalid
Lijie Li
Sima Singh
format Journal article
container_title ACS Omega
container_volume 7
container_issue 31
container_start_page 27079
publishDate 2022
institution Swansea University
issn 2470-1343
2470-1343
doi_str_mv 10.1021/acsomega.2c03645
publisher American Chemical Society (ACS)
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Electronic and Electrical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Aerospace, Civil, Electrical, General and Mechanical Engineering - Electronic and Electrical Engineering
document_store_str 1
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description Efficient and simple detection of chemical warfare agents (CWAs) is an essential step in minimizing the potentially lethal consequences of chemical weapons. CWAs are a family of organic chemicals that are used as chemical weapons because of their enormous severity and lethal effects when faced with unforeseen challenges. To stop the spread of CWAs, it is critical to develop a platform that detects them in a sensitive, timely, selective, and minimally invasive manner. Rapid advances in the demand for on-site sensors, metal nanoparticles, and biomarker identification for CWAs have made it possible to use fluorescence as a precise real-time and point-of-care (POCT) testing technique. For POCT-based applications, the new capabilities of micro- and nanomotors offer enormous prospects. In recent decades, significant progress has been made in the design of fluorescent sensors and the further development of noble metal nanoparticles for the detection of organophosphorus CWAs, as described in this review. Through this work, recent attempts to fabricate sensors that can detect organophosphorus CWAs through changes in their fluorescence properties have been summarized. Finally, an integrated outlook on how noble metal nanoparticles could be used to develop smart sensors for organophosphorus CWAs that communicate with and control electronic devices to monitor and improve the health of individuals.
published_date 2022-08-09T04:20:39Z
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score 11.013171

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