Wearable Light Sensors Based on Unique Features of a Natural Biochrome

Wilson, Daniel J.; Martin-Martinez, Francisco; Deravi, Leila F.

doi:10.1021/acssensors.1c02342

Journal article 822 views

Wearable Light Sensors Based on Unique Features of a Natural Biochrome

Daniel J. Wilson

, Francisco Martin-Martinez

, Leila F. Deravi

ACS Sensors, Volume: 7, Issue: 2, Pages: 523 - 533

Swansea University Author: Francisco Martin-Martinez

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DOI (Published version): 10.1021/acssensors.1c02342

Abstract

Overexposure to complete solar radiation (combined ultraviolet, visible, and infrared) is correlated with several harmful biological consequences including hyperpigmentation, skin cancer, eye damage, and immune suppression. With limited effective therapeutic options available for these conditions, s...

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Published in:	ACS Sensors
ISSN:	2379-3694 2379-3694
Published:	American Chemical Society (ACS) 2022
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa60574
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first_indexed	2022-07-21T10:23:58Z
last_indexed	2023-01-13T19:20:48Z
id	cronfa60574
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spelling	2022-10-27T14:48:27.7569995 v2 60574 2022-07-21 Wearable Light Sensors Based on Unique Features of a Natural Biochrome a5907aac618ec107662c888f6ead0e4a 0000-0001-7149-5512 Francisco Martin-Martinez Francisco Martin-Martinez true false 2022-07-21 CHEM Overexposure to complete solar radiation (combined ultraviolet, visible, and infrared) is correlated with several harmful biological consequences including hyperpigmentation, skin cancer, eye damage, and immune suppression. With limited effective therapeutic options available for these conditions, significant efforts have been directed toward promoting preventative habits. Recently, wearable solar radiometers have emerged as practical tools for managing personal exposure to sunlight. However, designing simple and inexpensive sensors that can measure energy across multiple spectral regions without incorporating electronic components remains challenging, largely due to inherent spectral limitations of photoresponsive indicators. In this work, we report the design, fabrication, and characterization of wearable radiation sensors that leverage an unexpected feature of a natural biochrome, xanthommatin―its innate sensitivity to both ultraviolet and visible through near-infrared radiation. We found that xanthommatin-based sensors undergo a visible shift from yellow to red in the presence of complete sunlight. This color change is driven by intrinsic photoreduction of the molecule, which we investigated using computational modeling and supplemented by radiation-driven formation of complementary reducing agents. These sensors are responsive to ermatologically relevant doses of erythemally weighted radiation, as well as cumulative doses of high-energy ultraviolet radiation used for germicidal sterilization. We incorporated these miniature sensors into pressure-activated microfluidic systems to illustrate on-demand activation of a wearable and mountable form factor. When taken together, our findings encompass an important advancement toward accessible, quantitative measurements of UVC and complete solar radiation for a variety of use cases. Journal Article ACS Sensors 7 2 523 533 American Chemical Society (ACS) 2379-3694 2379-3694 bioinspired, sensor, paper-based, wearable, microfluidics, DFT 25 2 2022 2022-02-25 10.1021/acssensors.1c02342 COLLEGE NANME Chemistry COLLEGE CODE CHEM Swansea University 2022-10-27T14:48:27.7569995 2022-07-21T11:19:57.8319708 Faculty of Science and Engineering School of Engineering and Applied Sciences - Chemistry Daniel J. Wilson 0000-0002-1472-9623 1 Francisco Martin-Martinez 0000-0001-7149-5512 2 Leila F. Deravi 0000-0003-3226-2470 3
title	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
spellingShingle	Wearable Light Sensors Based on Unique Features of a Natural Biochrome Francisco Martin-Martinez
title_short	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
title_full	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
title_fullStr	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
title_full_unstemmed	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
title_sort	Wearable Light Sensors Based on Unique Features of a Natural Biochrome
author_id_str_mv	a5907aac618ec107662c888f6ead0e4a
author_id_fullname_str_mv	a5907aac618ec107662c888f6ead0e4a_***_Francisco Martin-Martinez
author	Francisco Martin-Martinez
author2	Daniel J. Wilson Francisco Martin-Martinez Leila F. Deravi
format	Journal article
container_title	ACS Sensors
container_volume	7
container_issue	2
container_start_page	523
publishDate	2022
institution	Swansea University
issn	2379-3694 2379-3694
doi_str_mv	10.1021/acssensors.1c02342
publisher	American Chemical Society (ACS)
college_str	Faculty of Science and Engineering
hierarchytype
hierarchy_top_id	facultyofscienceandengineering
hierarchy_top_title	Faculty of Science and Engineering
hierarchy_parent_id	facultyofscienceandengineering
hierarchy_parent_title	Faculty of Science and Engineering
department_str	School of Engineering and Applied Sciences - Chemistry{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Chemistry
document_store_str	0
active_str	0
description	Overexposure to complete solar radiation (combined ultraviolet, visible, and infrared) is correlated with several harmful biological consequences including hyperpigmentation, skin cancer, eye damage, and immune suppression. With limited effective therapeutic options available for these conditions, significant efforts have been directed toward promoting preventative habits. Recently, wearable solar radiometers have emerged as practical tools for managing personal exposure to sunlight. However, designing simple and inexpensive sensors that can measure energy across multiple spectral regions without incorporating electronic components remains challenging, largely due to inherent spectral limitations of photoresponsive indicators. In this work, we report the design, fabrication, and characterization of wearable radiation sensors that leverage an unexpected feature of a natural biochrome, xanthommatin―its innate sensitivity to both ultraviolet and visible through near-infrared radiation. We found that xanthommatin-based sensors undergo a visible shift from yellow to red in the presence of complete sunlight. This color change is driven by intrinsic photoreduction of the molecule, which we investigated using computational modeling and supplemented by radiation-driven formation of complementary reducing agents. These sensors are responsive to ermatologically relevant doses of erythemally weighted radiation, as well as cumulative doses of high-energy ultraviolet radiation used for germicidal sterilization. We incorporated these miniature sensors into pressure-activated microfluidic systems to illustrate on-demand activation of a wearable and mountable form factor. When taken together, our findings encompass an important advancement toward accessible, quantitative measurements of UVC and complete solar radiation for a variety of use cases.
published_date	2022-02-25T04:18:48Z
_version_	1763754249366274048
score	11.037166

Wearable Light Sensors Based on Unique Features of a Natural Biochrome

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