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Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study

Bridie Evans Orcid Logo, Ashley Akbari Orcid Logo, Rowena Bailey, Lesley Bethell, Samantha Bufton, Andrew Carson-Stevens Orcid Logo, Lucy Dixon, Adrian Edwards Orcid Logo, Ann John Orcid Logo, Stephen Jolles, Mark Kingston Orcid Logo, Jane Lyons, Ronan Lyons Orcid Logo, Alison Porter Orcid Logo, Berni Sewell Orcid Logo, Cathy Thornton Orcid Logo, Alan Watkins Orcid Logo, Tony Whiffen Orcid Logo, Helen Snooks Orcid Logo

BMJ Open, Volume: 12, Issue: 9, Start page: e059813

Swansea University Authors: Bridie Evans Orcid Logo, Ashley Akbari Orcid Logo, Rowena Bailey, Ann John Orcid Logo, Mark Kingston Orcid Logo, Jane Lyons, Ronan Lyons Orcid Logo, Alison Porter Orcid Logo, Berni Sewell Orcid Logo, Cathy Thornton Orcid Logo, Alan Watkins Orcid Logo, Helen Snooks Orcid Logo

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DOI (Published version): 10.1136/bmjopen-2021-059813

Abstract

Introduction Shielding aimed to protect those predicted to be at highest risk from COVID-19 and was uniquely implemented in the UK during the COVID-19 pandemic. Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were indiv...

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Published in: BMJ Open
ISSN: 2044-6055 2044-6055
Published: BMJ 2022
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Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. This study will generate a logic model of the intervention and evaluate the effects and costs of shielding to inform policy development and delivery during future pandemics.Methods and analysis This is a quasiexperimental study undertaken in Wales where records for people who were identified for shielding were already anonymously linked into integrated data systems for public health decision-making. We will: interview policy-makers to understand rationale for shielding advice to inform analysis and interpretation of results; use anonymised individual-level data to select people identified for shielding advice in March 2020 and a matched cohort, from routine electronic health data sources, to compare outcomes; survey a stratified random sample of each group about activities and quality of life at 12 months; use routine and newly collected blood data to assess immunity; interview people who were identified for shielding and their carers and NHS staff who delivered healthcare during shielding, to explore compliance and experiences; collect healthcare resource use data to calculate implementation costs and cost&#x2013;consequences. Our team includes people who were shielding, who used their experience to help design and deliver this study.Ethics and dissemination The study has received approval from the Newcastle North Tyneside 2 Research Ethics Committee (IRAS 295050). We will disseminate results directly to UK government policy-makers, publish in peer-reviewed journals, present at scientific and policy conferences and share accessible summaries of results online and through public and patient networks.</abstract><type>Journal Article</type><journal>BMJ Open</journal><volume>12</volume><journalNumber>9</journalNumber><paginationStart>e059813</paginationStart><paginationEnd/><publisher>BMJ</publisher><placeOfPublication/><isbnPrint/><isbnElectronic/><issnPrint>2044-6055</issnPrint><issnElectronic>2044-6055</issnElectronic><keywords/><publishedDay>8</publishedDay><publishedMonth>9</publishedMonth><publishedYear>2022</publishedYear><publishedDate>2022-09-08</publishedDate><doi>10.1136/bmjopen-2021-059813</doi><url/><notes/><college>COLLEGE NANME</college><department>Health Data Science</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>HDAT</DepartmentCode><institution>Swansea University</institution><apcterm>SU Library paid the OA fee (TA Institutional Deal)</apcterm><funders>ADR Wales - ES/S007393/1; Health Data Research UK - HDR UK Ltd (HDR-9006); Medical Research Council - MR/V028367/1; National Core Studies Immunity (NCSi4P) Programme - UoB WT Ref: 1745068</funders><projectreference/><lastEdited>2022-11-17T12:01:05.5779942</lastEdited><Created>2022-07-12T10:00:06.7876329</Created><path><level id="1">Faculty of Medicine, Health and Life Sciences</level><level id="2">Swansea University Medical School - Medicine</level></path><authors><author><firstname>Bridie</firstname><surname>Evans</surname><orcid>0000-0003-0293-0888</orcid><order>1</order></author><author><firstname>Ashley</firstname><surname>Akbari</surname><orcid>0000-0003-0814-0801</orcid><order>2</order></author><author><firstname>Rowena</firstname><surname>Bailey</surname><order>3</order></author><author><firstname>Lesley</firstname><surname>Bethell</surname><order>4</order></author><author><firstname>Samantha</firstname><surname>Bufton</surname><order>5</order></author><author><firstname>Andrew</firstname><surname>Carson-Stevens</surname><orcid>0000-0002-7580-7699</orcid><order>6</order></author><author><firstname>Lucy</firstname><surname>Dixon</surname><order>7</order></author><author><firstname>Adrian</firstname><surname>Edwards</surname><orcid>0000-0002-6228-4446</orcid><order>8</order></author><author><firstname>Ann</firstname><surname>John</surname><orcid>0000-0002-5657-6995</orcid><order>9</order></author><author><firstname>Stephen</firstname><surname>Jolles</surname><order>10</order></author><author><firstname>Mark</firstname><surname>Kingston</surname><orcid>0000-0003-2242-4210</orcid><order>11</order></author><author><firstname>Jane</firstname><surname>Lyons</surname><orcid/><order>12</order></author><author><firstname>Ronan</firstname><surname>Lyons</surname><orcid>0000-0001-5225-000X</orcid><order>13</order></author><author><firstname>Alison</firstname><surname>Porter</surname><orcid>0000-0002-3408-7007</orcid><order>14</order></author><author><firstname>Berni</firstname><surname>Sewell</surname><orcid>0000-0001-5471-922X</orcid><order>15</order></author><author><firstname>Cathy</firstname><surname>Thornton</surname><orcid>0000-0002-5153-573X</orcid><order>16</order></author><author><firstname>Alan</firstname><surname>Watkins</surname><orcid>0000-0003-3804-1943</orcid><order>17</order></author><author><firstname>Tony</firstname><surname>Whiffen</surname><orcid>0000-0002-9329-6685</orcid><order>18</order></author><author><firstname>Helen</firstname><surname>Snooks</surname><orcid>0000-0003-0173-8843</orcid><order>19</order></author></authors><documents><document><filename>60455__25814__cf2943abbde14dde8e34b875d3d3b3f9.pdf</filename><originalFilename>60455.pdf</originalFilename><uploaded>2022-11-17T11:59:30.7689239</uploaded><type>Output</type><contentLength>1320082</contentLength><contentType>application/pdf</contentType><version>Version of Record</version><cronfaStatus>true</cronfaStatus><documentNotes>&#xA9; Author(s) (or their employer(s)) 2022. 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spelling 2022-11-17T12:01:05.5779942 v2 60455 2022-07-12 Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study 6098eddc58e31ac2f3e070cb839faa6a 0000-0003-0293-0888 Bridie Evans Bridie Evans true false aa1b025ec0243f708bb5eb0a93d6fb52 0000-0003-0814-0801 Ashley Akbari Ashley Akbari true false 455e2c1e6193448f6269b9e72acaf865 Rowena Bailey Rowena Bailey true false ed8a9c37bd7b7235b762d941ef18ee55 0000-0002-5657-6995 Ann John Ann John true false 3442763d6ff0467963e0792d2b5404fa 0000-0003-2242-4210 Mark Kingston Mark Kingston true false 1b74fa5125a88451c52c45bcf20e0b47 Jane Lyons Jane Lyons true false 83efcf2a9dfcf8b55586999d3d152ac6 0000-0001-5225-000X Ronan Lyons Ronan Lyons true false fcc861ec479a79f7fb9befb13192238b 0000-0002-3408-7007 Alison Porter Alison Porter true false f6a4af2cfa4275d2a8ebba292fa14421 0000-0001-5471-922X Berni Sewell Berni Sewell true false c71a7a4be7361094d046d312202bce0c 0000-0002-5153-573X Cathy Thornton Cathy Thornton true false 81fc05c9333d9df41b041157437bcc2f 0000-0003-3804-1943 Alan Watkins Alan Watkins true false ab23c5e0111b88427a155a1f495861d9 0000-0003-0173-8843 Helen Snooks Helen Snooks true false 2022-07-12 HDAT Introduction Shielding aimed to protect those predicted to be at highest risk from COVID-19 and was uniquely implemented in the UK during the COVID-19 pandemic. Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. This study will generate a logic model of the intervention and evaluate the effects and costs of shielding to inform policy development and delivery during future pandemics.Methods and analysis This is a quasiexperimental study undertaken in Wales where records for people who were identified for shielding were already anonymously linked into integrated data systems for public health decision-making. We will: interview policy-makers to understand rationale for shielding advice to inform analysis and interpretation of results; use anonymised individual-level data to select people identified for shielding advice in March 2020 and a matched cohort, from routine electronic health data sources, to compare outcomes; survey a stratified random sample of each group about activities and quality of life at 12 months; use routine and newly collected blood data to assess immunity; interview people who were identified for shielding and their carers and NHS staff who delivered healthcare during shielding, to explore compliance and experiences; collect healthcare resource use data to calculate implementation costs and cost–consequences. Our team includes people who were shielding, who used their experience to help design and deliver this study.Ethics and dissemination The study has received approval from the Newcastle North Tyneside 2 Research Ethics Committee (IRAS 295050). We will disseminate results directly to UK government policy-makers, publish in peer-reviewed journals, present at scientific and policy conferences and share accessible summaries of results online and through public and patient networks. Journal Article BMJ Open 12 9 e059813 BMJ 2044-6055 2044-6055 8 9 2022 2022-09-08 10.1136/bmjopen-2021-059813 COLLEGE NANME Health Data Science COLLEGE CODE HDAT Swansea University SU Library paid the OA fee (TA Institutional Deal) ADR Wales - ES/S007393/1; Health Data Research UK - HDR UK Ltd (HDR-9006); Medical Research Council - MR/V028367/1; National Core Studies Immunity (NCSi4P) Programme - UoB WT Ref: 1745068 2022-11-17T12:01:05.5779942 2022-07-12T10:00:06.7876329 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Bridie Evans 0000-0003-0293-0888 1 Ashley Akbari 0000-0003-0814-0801 2 Rowena Bailey 3 Lesley Bethell 4 Samantha Bufton 5 Andrew Carson-Stevens 0000-0002-7580-7699 6 Lucy Dixon 7 Adrian Edwards 0000-0002-6228-4446 8 Ann John 0000-0002-5657-6995 9 Stephen Jolles 10 Mark Kingston 0000-0003-2242-4210 11 Jane Lyons 12 Ronan Lyons 0000-0001-5225-000X 13 Alison Porter 0000-0002-3408-7007 14 Berni Sewell 0000-0001-5471-922X 15 Cathy Thornton 0000-0002-5153-573X 16 Alan Watkins 0000-0003-3804-1943 17 Tony Whiffen 0000-0002-9329-6685 18 Helen Snooks 0000-0003-0173-8843 19 60455__25814__cf2943abbde14dde8e34b875d3d3b3f9.pdf 60455.pdf 2022-11-17T11:59:30.7689239 Output 1320082 application/pdf Version of Record true © Author(s) (or their employer(s)) 2022. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license true eng https://creativecommons.org/licenses/by/4.0/
title Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
spellingShingle Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
Bridie Evans
Ashley Akbari
Rowena Bailey
Ann John
Mark Kingston
Jane Lyons
Ronan Lyons
Alison Porter
Berni Sewell
Cathy Thornton
Alan Watkins
Helen Snooks
title_short Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
title_full Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
title_fullStr Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
title_full_unstemmed Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
title_sort Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study
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author_id_fullname_str_mv 6098eddc58e31ac2f3e070cb839faa6a_***_Bridie Evans
aa1b025ec0243f708bb5eb0a93d6fb52_***_Ashley Akbari
455e2c1e6193448f6269b9e72acaf865_***_Rowena Bailey
ed8a9c37bd7b7235b762d941ef18ee55_***_Ann John
3442763d6ff0467963e0792d2b5404fa_***_Mark Kingston
1b74fa5125a88451c52c45bcf20e0b47_***_Jane Lyons
83efcf2a9dfcf8b55586999d3d152ac6_***_Ronan Lyons
fcc861ec479a79f7fb9befb13192238b_***_Alison Porter
f6a4af2cfa4275d2a8ebba292fa14421_***_Berni Sewell
c71a7a4be7361094d046d312202bce0c_***_Cathy Thornton
81fc05c9333d9df41b041157437bcc2f_***_Alan Watkins
ab23c5e0111b88427a155a1f495861d9_***_Helen Snooks
author Bridie Evans
Ashley Akbari
Rowena Bailey
Ann John
Mark Kingston
Jane Lyons
Ronan Lyons
Alison Porter
Berni Sewell
Cathy Thornton
Alan Watkins
Helen Snooks
author2 Bridie Evans
Ashley Akbari
Rowena Bailey
Lesley Bethell
Samantha Bufton
Andrew Carson-Stevens
Lucy Dixon
Adrian Edwards
Ann John
Stephen Jolles
Mark Kingston
Jane Lyons
Ronan Lyons
Alison Porter
Berni Sewell
Cathy Thornton
Alan Watkins
Tony Whiffen
Helen Snooks
format Journal article
container_title BMJ Open
container_volume 12
container_issue 9
container_start_page e059813
publishDate 2022
institution Swansea University
issn 2044-6055
2044-6055
doi_str_mv 10.1136/bmjopen-2021-059813
publisher BMJ
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 1
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description Introduction Shielding aimed to protect those predicted to be at highest risk from COVID-19 and was uniquely implemented in the UK during the COVID-19 pandemic. Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. This study will generate a logic model of the intervention and evaluate the effects and costs of shielding to inform policy development and delivery during future pandemics.Methods and analysis This is a quasiexperimental study undertaken in Wales where records for people who were identified for shielding were already anonymously linked into integrated data systems for public health decision-making. We will: interview policy-makers to understand rationale for shielding advice to inform analysis and interpretation of results; use anonymised individual-level data to select people identified for shielding advice in March 2020 and a matched cohort, from routine electronic health data sources, to compare outcomes; survey a stratified random sample of each group about activities and quality of life at 12 months; use routine and newly collected blood data to assess immunity; interview people who were identified for shielding and their carers and NHS staff who delivered healthcare during shielding, to explore compliance and experiences; collect healthcare resource use data to calculate implementation costs and cost–consequences. Our team includes people who were shielding, who used their experience to help design and deliver this study.Ethics and dissemination The study has received approval from the Newcastle North Tyneside 2 Research Ethics Committee (IRAS 295050). We will disseminate results directly to UK government policy-makers, publish in peer-reviewed journals, present at scientific and policy conferences and share accessible summaries of results online and through public and patient networks.
published_date 2022-09-08T04:18:35Z
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