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Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria
Engy A. Abdel-Rahman,
Salma Hosseiny,
Abdullah Aaliya ,
Mohamed Adel,
Basma Yasseen ,
Abdelrahman Al-Okda ,
Yasmine Radwan,
Saber H. Saber ,
Nada Elkholy ,
Eslam Elhanafy ,
Emily E. Walker,
Juan P. Zuniga-Hertz,
Hemal H. Patel,
Helen Griffiths,
Sameh S. Ali
Journal of Advanced Research, Volume: 31, Pages: 35 - 47
Swansea University Author: Helen Griffiths
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DOI (Published version): 10.1016/j.jare.2021.01.006
Abstract
Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability to cardiovascular events.
Published in: | Journal of Advanced Research |
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ISSN: | 2090-1232 |
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Elsevier BV
2021
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URI: | https://cronfa.swan.ac.uk/Record/cronfa60385 |
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2022-08-11T12:06:11.4040383 v2 60385 2022-07-05 Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria 0366ea9a689b222146b7d63c6baf8427 Helen Griffiths Helen Griffiths true false 2022-07-05 SMT Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability to cardiovascular events. Journal Article Journal of Advanced Research 31 35 47 Elsevier BV 2090-1232 Heart, Mitochondria function, Calcium dynamics, Hydrogen peroxide, Diurnal, Clock genes 1 7 2021 2021-07-01 10.1016/j.jare.2021.01.006 Appendix A. Supplementary material via https://doi.org/10.1016/j.jare.2021.01.006 COLLEGE NANME Senior Leadership Team COLLEGE CODE SMT Swansea University This work was supported by a National Research Grant no. 6364 by the Science and Technology Development Fund, Egypt, awarded to SSA. SSA and EAA would like to acknowledge the support provided by Horizon 2020, COST Action CA15203 ‘MitoEAGLE’. This work was supported by grants from the National Institutes of Health (NIH) (HL091071, to H. H. Patel), and the Veterans Affairs (BX001963, to H. H. Patel). 2022-08-11T12:06:11.4040383 2022-07-05T13:43:04.6658957 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Engy A. Abdel-Rahman 1 Salma Hosseiny 2 Abdullah Aaliya 0000-0001-9165-842x 3 Mohamed Adel 4 Basma Yasseen 0000-0003-4187-0523 5 Abdelrahman Al-Okda 0000-0002-0352-7292 6 Yasmine Radwan 7 Saber H. Saber 0000-0003-1296-2023 8 Nada Elkholy 0000-0001-9665-1171 9 Eslam Elhanafy 0000-0002-0125-1958 10 Emily E. Walker 11 Juan P. Zuniga-Hertz 12 Hemal H. Patel 13 Helen Griffiths 14 Sameh S. Ali 15 60385__24453__10beb6a5c8274f2bb1721a1230f29730.pdf 60383.VOR.pdf 2022-07-05T14:58:51.7406095 Output 2086008 application/pdf Version of Record true This is an open access article under a Creative Commons CC BY-NC-ND license . true eng http://creativecommons.org/licenses/by-nc-nd/4.0/ |
title |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
spellingShingle |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria Helen Griffiths |
title_short |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
title_full |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
title_fullStr |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
title_full_unstemmed |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
title_sort |
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria |
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0366ea9a689b222146b7d63c6baf8427_***_Helen Griffiths |
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Helen Griffiths |
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Engy A. Abdel-Rahman Salma Hosseiny Abdullah Aaliya Mohamed Adel Basma Yasseen Abdelrahman Al-Okda Yasmine Radwan Saber H. Saber Nada Elkholy Eslam Elhanafy Emily E. Walker Juan P. Zuniga-Hertz Hemal H. Patel Helen Griffiths Sameh S. Ali |
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Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability to cardiovascular events. |
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2021-07-01T14:16:03Z |
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