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Stroke in Older Adults Living in Care Homes: Results From a National Data Linkage Study in Wales

Stephanie L. Harrison Orcid Logo, Gregory Y.H. Lip, Ashley Akbari Orcid Logo, Fatemeh Torabi Orcid Logo, Leona A. Ritchie, Asangaedem Akpan, Julian Halcox Orcid Logo, Sarah Rodgers, Joe Hollinghurst, Daniel Harris, Deirdre A. Lane

Journal of the American Medical Directors Association, Volume: 23, Issue: 9, Pages: 1548 - 1554.e11

Swansea University Authors: Ashley Akbari Orcid Logo, Fatemeh Torabi Orcid Logo, Julian Halcox Orcid Logo, Joe Hollinghurst, Daniel Harris

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Abstract

ObjectivesTo determine the proportion of older people moving to care homes with a recent stroke, incidence of stroke after moving to a care home, mortality following stroke, and secondary stroke prevention management in older care home residents.DesignRetrospective cohort study using population-scal...

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Published in: Journal of the American Medical Directors Association
ISSN: 1525-8610
Published: Elsevier BV 2022
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa60151
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Abstract: ObjectivesTo determine the proportion of older people moving to care homes with a recent stroke, incidence of stroke after moving to a care home, mortality following stroke, and secondary stroke prevention management in older care home residents.DesignRetrospective cohort study using population-scale individual-level linked data sources between 2003 and 2018 in the Secure Anonymized Information Linkage (SAIL) Databank.Setting and ParticipantsPeople aged ≥65 years residing in long-term care homes in Wales.MethodsCompeting risk models and logistic regression models were used to examine the association between prior stroke, incident stroke, and mortality following stroke.ResultsOf 86,602 individuals, 7.0% (n = 6055) experienced a stroke in the 12 months prior to care home entry. The incidence of stroke within 12 months after entry to a care home was 26.2 per 1000 person-years [95% confidence interval (CI) 25.0, 27.5]. Previous stroke was associated with higher risk of incident stroke after moving to a care home (subdistribution hazard ratio 1.83, 95% CI 1.57, 2.13) and 30-day mortality following stroke (odds ratio 2.18, 95% CI 1.59, 2.98). Severe frailty was not significantly associated with risk of stroke or 30-day mortality following stroke. Secondary stroke prevention included statins (51.0%), antiplatelets (61.2%), anticoagulants (52.4% of those with atrial fibrillation), and antihypertensives (92.1% of those with hypertension).Conclusions and ImplicationsAt the time of care home entry, individuals with history of stroke in the previous 12 months are at a higher risk of incident stroke and mortality following an incident stroke. These individuals are frequently not prescribed medications for secondary stroke prevention. Further evidence is needed to determine the optimal care pathways for older people living in long-term care homes with history of stroke.
Keywords: Nursing homes; cerebrovascular disease; antiplatelets; anticoagulants
College: Faculty of Medicine, Health and Life Sciences
Funders: No specific funding was received for this work. This work was supported by Health Data Research UK, which receives its funding from HDR UK Ltd (HDR-9006) funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation (BHF) and the Wellcome Trust. This work was supported by the ADR Wales program of work. The ADR Wales program of work is aligned to the priority themes as identified in the Welsh Government's national strategy: Prosperity for All. ADR Wales brings together data science experts at Swansea University Medical School, staff from the Wales Institute of Social and Economic Research, Data and Methods (WISERD) at Cardiff University and specialist teams within the Welsh Government to develop new evidence which supports Prosperity for All by using the SAIL Databank at Swansea University, to link and Analyse anonymized data. ADR Wales is part of the Economic and Social Research Council (part of UK Research and Innovation) funded ADR UK (grant ES/S007393/1). Sarah Rodgers is part-funded by the National Institute for Health Research (NIHR) Applied Research Collaboration North West Coast (ARC NWC). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care.
Issue: 9
Start Page: 1548
End Page: 1554.e11