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Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective
Journal of Personalized Medicine, Volume: 12, Issue: 1, Start page: 86
Swansea University Authors: Shang-ming Zhou , Ronan Lyons , Sinead Brophy
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DOI (Published version): 10.3390/jpm12010086
Abstract
(1) Background: This study investigates influential risk factors for predicting 30-day readmission to hospital for Campylobacter infections (CI). (2) Methods: We linked general practitioner and hospital admission records of 13,006 patients with CI in Wales (1990−2015). An approach called TF-zR (term...
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2022
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2022-02-16T12:52:18.3350369 v2 59184 2022-01-14 Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective 118578a62021ba8ef61398da0a8750da 0000-0002-0719-9353 Shang-ming Zhou Shang-ming Zhou true false 83efcf2a9dfcf8b55586999d3d152ac6 0000-0001-5225-000X Ronan Lyons Ronan Lyons true false 84f5661b35a729f55047f9e793d8798b 0000-0001-7417-2858 Sinead Brophy Sinead Brophy true false 2022-01-14 BMS (1) Background: This study investigates influential risk factors for predicting 30-day readmission to hospital for Campylobacter infections (CI). (2) Methods: We linked general practitioner and hospital admission records of 13,006 patients with CI in Wales (1990−2015). An approach called TF-zR (term frequency-zRelevance) technique was presented to evaluates how relevant a clinical term is to a patient in a cohort characterized by coded health records. The zR is a supervised term-weighting metric to assign weight to a term based on relative frequencies of the term across different classes. Cost-sensitive classifier with swarm optimization and weighted subset learning was integrated to identify influential clinical signals as predictors and optimal model for readmission prediction. (3) Results: From a pool of up to 17,506 variables, 33 most predictive factors were identified, including age, gender, Townsend deprivation quintiles, comorbidities, medications, and procedures. The predictive model predicted readmission with 73% sensitivity and 54% specificity. Variables associated with readmission included male gender, recurrent tonsillitis, non-healing open wounds, operation for in-gown toenails. Cystitis, paracetamol/codeine use, age (21−25), and heliclear triple pack use, were associated with a lower risk of readmission. (4) Conclusions: This study gives a profile of clustered variables that are predictive of readmission associated with campylobacteriosis. Journal Article Journal of Personalized Medicine 12 1 86 MDPI AG 2075-4426 hospitalisation, readmission, Campylobacter infections, machine learning, text mining, feature selection, electronic health records 10 1 2022 2022-01-10 10.3390/jpm12010086 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University SU College/Department paid the OA fee This work was supported by the Health Data Research UK (NIWA1). This analysis was also undertaken with the support of the National Centre for Population Health and Wellbeing Research (NCPHWR) via Health and Care Research Wales (grant ref. CA02). 2022-02-16T12:52:18.3350369 2022-01-14T19:35:05.4102867 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Shang-ming Zhou 0000-0002-0719-9353 1 Ronan Lyons 0000-0001-5225-000X 2 Muhammad A. Rahman 3 Alexander Holborow 4 Sinead Brophy 0000-0001-7417-2858 5 59184__22147__e5404844a86a4daea92f318c05da2c01.pdf jpm-12-00086.pdf 2022-01-14T19:35:05.4098894 Output 1802259 application/pdf Version of Record true Copyright: © 2022 by the authors. This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license true eng https://creativecommons.org/licenses/by/4.0/ |
title |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
spellingShingle |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective Shang-ming Zhou Ronan Lyons Sinead Brophy |
title_short |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
title_full |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
title_fullStr |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
title_full_unstemmed |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
title_sort |
Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective |
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118578a62021ba8ef61398da0a8750da 83efcf2a9dfcf8b55586999d3d152ac6 84f5661b35a729f55047f9e793d8798b |
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118578a62021ba8ef61398da0a8750da_***_Shang-ming Zhou 83efcf2a9dfcf8b55586999d3d152ac6_***_Ronan Lyons 84f5661b35a729f55047f9e793d8798b_***_Sinead Brophy |
author |
Shang-ming Zhou Ronan Lyons Sinead Brophy |
author2 |
Shang-ming Zhou Ronan Lyons Muhammad A. Rahman Alexander Holborow Sinead Brophy |
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Journal of Personalized Medicine |
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MDPI AG |
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description |
(1) Background: This study investigates influential risk factors for predicting 30-day readmission to hospital for Campylobacter infections (CI). (2) Methods: We linked general practitioner and hospital admission records of 13,006 patients with CI in Wales (1990−2015). An approach called TF-zR (term frequency-zRelevance) technique was presented to evaluates how relevant a clinical term is to a patient in a cohort characterized by coded health records. The zR is a supervised term-weighting metric to assign weight to a term based on relative frequencies of the term across different classes. Cost-sensitive classifier with swarm optimization and weighted subset learning was integrated to identify influential clinical signals as predictors and optimal model for readmission prediction. (3) Results: From a pool of up to 17,506 variables, 33 most predictive factors were identified, including age, gender, Townsend deprivation quintiles, comorbidities, medications, and procedures. The predictive model predicted readmission with 73% sensitivity and 54% specificity. Variables associated with readmission included male gender, recurrent tonsillitis, non-healing open wounds, operation for in-gown toenails. Cystitis, paracetamol/codeine use, age (21−25), and heliclear triple pack use, were associated with a lower risk of readmission. (4) Conclusions: This study gives a profile of clustered variables that are predictive of readmission associated with campylobacteriosis. |
published_date |
2022-01-10T04:16:17Z |
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11.036837 |