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Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales

Mohammad Al Sallakh Orcid Logo, Shanya Sivakumaran, Sharon Kennedy, Eleftheria Vasileiou, Ronan Lyons Orcid Logo, Chris Robertson, Aziz Sheikh, Gwyneth Davies Orcid Logo, (on behalf of the EAVE II Collaborators)

BMC Medicine, Volume: 19, Issue: 1

Swansea University Authors: Mohammad Al Sallakh Orcid Logo, Shanya Sivakumaran, Ronan Lyons Orcid Logo, Gwyneth Davies Orcid Logo

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DOI (Published version): 10.1186/s12916-021-02000-w

Abstract

The COVID-19 pandemic and ensuing national lockdowns have dramatically changed the healthcare landscape. The pandemic’s impact on people with chronic obstructive pulmonary disease (COPD) remains poorly understood. We hypothesised that the UK-wide lockdown restrictions were associated with reductions...

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Published in: BMC Medicine
ISSN: 1741-7015
Published: Springer Science and Business Media LLC 2021
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URI: https://cronfa.swan.ac.uk/Record/cronfa57990
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spelling 2021-10-20T16:49:35.3857857 v2 57990 2021-09-20 Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales 6efc53139ba1416418a6c6e584a25f2d 0000-0002-8333-7279 Mohammad Al Sallakh Mohammad Al Sallakh true false 2799501bc10dea3008518d41ca0339a2 Shanya Sivakumaran Shanya Sivakumaran true false 83efcf2a9dfcf8b55586999d3d152ac6 0000-0001-5225-000X Ronan Lyons Ronan Lyons true false 92d69cf8519a334ced3f55142c811d95 0000-0003-1218-1008 Gwyneth Davies Gwyneth Davies true false 2021-09-20 HDAT The COVID-19 pandemic and ensuing national lockdowns have dramatically changed the healthcare landscape. The pandemic’s impact on people with chronic obstructive pulmonary disease (COPD) remains poorly understood. We hypothesised that the UK-wide lockdown restrictions were associated with reductions in severe COPD exacerbations. We provide the first national level analyses of the impact of the COVID-19 pandemic and first lockdown on severe COPD exacerbations resulting in emergency hospital admissions and/or leading to death as well as those recorded in primary care or emergency departments. Journal Article BMC Medicine 19 1 Springer Science and Business Media LLC 1741-7015 Acute exacerbation of chronic obstructive pulmonary disease, COVID-19 lockdown 17 5 2021 2021-05-17 10.1186/s12916-021-02000-w COLLEGE NANME Health Data Science COLLEGE CODE HDAT Swansea University SU College/Department paid the OA fee This study was funded by the Medical Research Council (MR/R008345/1) with the support of BREATHE – The Health Data Research Hub for Respiratory Health [MC_PC_19004], which is funded through the UK Research and Innovation Industrial Strategy Challenge Fund and delivered through Health Data Research UK. The funders had no role in the design of the study, collection, analysis, and interpretation of data, or in writing the manuscript. MR/R008345/1 2021-10-20T16:49:35.3857857 2021-09-20T18:17:45.1446353 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Mohammad Al Sallakh 0000-0002-8333-7279 1 Shanya Sivakumaran 2 Sharon Kennedy 3 Eleftheria Vasileiou 4 Ronan Lyons 0000-0001-5225-000X 5 Chris Robertson 6 Aziz Sheikh 7 Gwyneth Davies 0000-0003-1218-1008 8 (on behalf of the EAVE II Collaborators) 9 57990__20950__9e589c7e7525473682e0c8e388775886.pdf 57990.VOR.pdf 2021-09-21T09:06:34.1419639 Output 690890 application/pdf Version of Record true Copyright: The Authors. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. true eng http://creativecommons.org/licenses/by/4.0/ 87 Mohammad A. Alsallakh / SAIL 0000-0002-8333-7279 false 4 true
title Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
spellingShingle Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
Mohammad Al Sallakh
Shanya Sivakumaran
Ronan Lyons
Gwyneth Davies
title_short Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
title_full Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
title_fullStr Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
title_full_unstemmed Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
title_sort Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
author_id_str_mv 6efc53139ba1416418a6c6e584a25f2d
2799501bc10dea3008518d41ca0339a2
83efcf2a9dfcf8b55586999d3d152ac6
92d69cf8519a334ced3f55142c811d95
author_id_fullname_str_mv 6efc53139ba1416418a6c6e584a25f2d_***_Mohammad Al Sallakh
2799501bc10dea3008518d41ca0339a2_***_Shanya Sivakumaran
83efcf2a9dfcf8b55586999d3d152ac6_***_Ronan Lyons
92d69cf8519a334ced3f55142c811d95_***_Gwyneth Davies
author Mohammad Al Sallakh
Shanya Sivakumaran
Ronan Lyons
Gwyneth Davies
author2 Mohammad Al Sallakh
Shanya Sivakumaran
Sharon Kennedy
Eleftheria Vasileiou
Ronan Lyons
Chris Robertson
Aziz Sheikh
Gwyneth Davies
(on behalf of the EAVE II Collaborators)
format Journal article
container_title BMC Medicine
container_volume 19
container_issue 1
publishDate 2021
institution Swansea University
issn 1741-7015
doi_str_mv 10.1186/s12916-021-02000-w
publisher Springer Science and Business Media LLC
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 1
active_str 0
description The COVID-19 pandemic and ensuing national lockdowns have dramatically changed the healthcare landscape. The pandemic’s impact on people with chronic obstructive pulmonary disease (COPD) remains poorly understood. We hypothesised that the UK-wide lockdown restrictions were associated with reductions in severe COPD exacerbations. We provide the first national level analyses of the impact of the COVID-19 pandemic and first lockdown on severe COPD exacerbations resulting in emergency hospital admissions and/or leading to death as well as those recorded in primary care or emergency departments.
published_date 2021-05-17T04:14:09Z
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