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Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

Serena Massari, Chiara Bertagnin, Maria Chiara Pismataro, Anna Donnadio, Giulio Nannetti Orcid Logo, Tommaso Felicetti, Stefano Di Bona, Maria Giulia Nizi, Leonardo Tensi, Giuseppe Manfroni, Maria Isabel Loza, Stefano Sabatini, Violetta Cecchetti, Jose Brea, Laura Goracci, Arianna Loregian, Oriana Tabarrini

European Journal of Medicinal Chemistry, Volume: 209, Start page: 112944

Swansea University Author: Giulio Nannetti Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2021
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa57638
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Keywords: Influenza virus; PA-PB1 heterodimerization; RNA-Dependent RNA polymerase; Protein-protein interaction
College: Faculty of Medicine, Health and Life Sciences
Start Page: 112944