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Emerging nanomaterials for dental treatments

Zi Hong Mok Orcid Logo, Gordon Proctor, Maya Thanou

Emerging Topics in Life Sciences, Volume: 4, Issue: 6, Pages: 613 - 625

Swansea University Author: Zi Hong Mok Orcid Logo

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DOI (Published version): 10.1042/etls20200195

Abstract

The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, anti...

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Published in: Emerging Topics in Life Sciences
ISSN: 2397-8554 2397-8562
Published: Portland Press Ltd. 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa57635
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spelling 2021-09-20T10:23:03.4093945 v2 57635 2021-08-18 Emerging nanomaterials for dental treatments 4a0b8a58c748d6a2c87a54f263f4d397 0000-0002-1231-5048 Zi Hong Mok Zi Hong Mok true false 2021-08-18 PHAR The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, antimicrobial activity, local anaesthesia, anti-inflammation, osteoconductivity and stem cell differentiation. Besides the applications on dental tissues, nanoparticles have been used to enhance the mechanical properties of dental composites, improving their bonding and anchorage and reducing friction. The small particle size allows for enhanced permeation into deeper lesions, and reduction in porosities of dental composites for higher mechanical strength. The large surface area to volume ratio allows for enhanced bioactivity such as bonding and integration, and more intense action towards microorganisms. Controlled release of encapsulated bioactive molecules such as drugs and growth factors enables them to be delivered more precisely, with site-targeted delivery for localised treatments. These properties have benefitted across multiple fields within dentistry, including periodontology and endodontics and reengineering of dental prosthetics and braces. This review summarises the current literature on the emerging field of nanomaterials for dental treatments. Journal Article Emerging Topics in Life Sciences 4 6 613 625 Portland Press Ltd. 2397-8554 2397-8562 endodontics, nanomaterials, orthodontics, periodontics, prosthodontics, remineralisation 17 12 2020 2020-12-17 10.1042/etls20200195 COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2021-09-20T10:23:03.4093945 2021-08-18T11:06:32.5082315 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Zi Hong Mok 0000-0002-1231-5048 1 Gordon Proctor 2 Maya Thanou 3 57635__20932__64fd9a9121284258a76e61092f14f6aa.pdf 57635.pdf 2021-09-20T10:21:57.1341513 Output 1794464 application/pdf Version of Record true © 2020 The Author(s). This is an open access article distributed under the Creative Commons Attribution License 4.0 (CC BY) true eng https://creativecommons.org/licenses/by/4.0/
title Emerging nanomaterials for dental treatments
spellingShingle Emerging nanomaterials for dental treatments
Zi Hong Mok
title_short Emerging nanomaterials for dental treatments
title_full Emerging nanomaterials for dental treatments
title_fullStr Emerging nanomaterials for dental treatments
title_full_unstemmed Emerging nanomaterials for dental treatments
title_sort Emerging nanomaterials for dental treatments
author_id_str_mv 4a0b8a58c748d6a2c87a54f263f4d397
author_id_fullname_str_mv 4a0b8a58c748d6a2c87a54f263f4d397_***_Zi Hong Mok
author Zi Hong Mok
author2 Zi Hong Mok
Gordon Proctor
Maya Thanou
format Journal article
container_title Emerging Topics in Life Sciences
container_volume 4
container_issue 6
container_start_page 613
publishDate 2020
institution Swansea University
issn 2397-8554
2397-8562
doi_str_mv 10.1042/etls20200195
publisher Portland Press Ltd.
college_str Faculty of Medicine, Health and Life Sciences
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hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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description The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, antimicrobial activity, local anaesthesia, anti-inflammation, osteoconductivity and stem cell differentiation. Besides the applications on dental tissues, nanoparticles have been used to enhance the mechanical properties of dental composites, improving their bonding and anchorage and reducing friction. The small particle size allows for enhanced permeation into deeper lesions, and reduction in porosities of dental composites for higher mechanical strength. The large surface area to volume ratio allows for enhanced bioactivity such as bonding and integration, and more intense action towards microorganisms. Controlled release of encapsulated bioactive molecules such as drugs and growth factors enables them to be delivered more precisely, with site-targeted delivery for localised treatments. These properties have benefitted across multiple fields within dentistry, including periodontology and endodontics and reengineering of dental prosthetics and braces. This review summarises the current literature on the emerging field of nanomaterials for dental treatments.
published_date 2020-12-17T04:13:31Z
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