The e-psychonaut drugs’ psychopharmacology

Schifano, Fabrizio; Chiappini, Stefania; Corkery, John M.; Scherbaum, Norbert; Guirguis, Amira

doi:10.1016/j.coph.2021.02.008

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The e-psychonaut drugs’ psychopharmacology

Fabrizio Schifano, Stefania Chiappini, John M. Corkery, Norbert Scherbaum, Amira Guirguis

Current Opinion in Pharmacology, Volume: 57, Pages: 165 - 174

Swansea University Author: Amira Guirguis

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DOI (Published version): 10.1016/j.coph.2021.02.008

Abstract

The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g., synthetic cannabimimetics; synthetic opioids; novel stimulants; novel psychedelics; PCP/ketamine-like compounds; prescribed medicinal compounds; and popular psychotropic herbs/p...

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Published in:	Current Opinion in Pharmacology
ISSN:	1471-4892
Published:	UK Elsevier BV 2021
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa56315
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first_indexed	2021-02-24T12:21:23Z
last_indexed	2021-08-14T03:20:12Z
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spelling	2021-08-13T13:10:56.3484848 v2 56315 2021-02-24 The e-psychonaut drugs’ psychopharmacology b49270b9a0d580cf4f31f9a1b6c93f87 0000-0001-8255-0660 Amira Guirguis Amira Guirguis true false 2021-02-24 PHAR The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g., synthetic cannabimimetics; synthetic opioids; novel stimulants; novel psychedelics; PCP/ketamine-like compounds; prescribed medicinal compounds; and popular psychotropic herbs/plants) discussed by Internet-based, new/novel psychoactive substances (NPS) enthusiasts, ‘e-psychonauts’.Currently ongoing related in silico studies, followed by further in vitro and in vivo/preclinical studies, will hopefully provide important findings in terms of which molecules within each given NPS class may present with higher levels of receptor affinities, and hence clinical potency. Understanding the pharmacological characteristics/potency of those novel recreational molecules will hopefully help in predicting related NPS diffusion, morbidity, and possible lethality data. Journal Article Current Opinion in Pharmacology 57 165 174 Elsevier BV UK 1471-4892 e-psychonauts; psychopharmacology; addiction; new psychoactive substances; novel psychoactive substances; NPS; drug abuse 1 4 2021 2021-04-01 10.1016/j.coph.2021.02.008 COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2021-08-13T13:10:56.3484848 2021-02-24T12:12:59.1510234 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Fabrizio Schifano 1 Stefania Chiappini 2 John M. Corkery 3 Norbert Scherbaum 4 Amira Guirguis 0000-0001-8255-0660 5 56315__19465__87a88d1e01104082a6a08a07dbfd091a.pdf 56315.pdf 2021-03-10T13:18:20.9674392 Output 189264 application/pdf Accepted Manuscript true 2022-03-25T00:00:00.0000000 ©2021 All rights reserved. All article content, except where otherwise noted, is licensed under a Creative Commons Attribution Non-Commercial No Derivatives License (CC-BY-NC-ND) true eng http://creativecommons.org/licenses/by-nc-nd/4.0/
title	The e-psychonaut drugs’ psychopharmacology
spellingShingle	The e-psychonaut drugs’ psychopharmacology Amira Guirguis
title_short	The e-psychonaut drugs’ psychopharmacology
title_full	The e-psychonaut drugs’ psychopharmacology
title_fullStr	The e-psychonaut drugs’ psychopharmacology
title_full_unstemmed	The e-psychonaut drugs’ psychopharmacology
title_sort	The e-psychonaut drugs’ psychopharmacology
author_id_str_mv	b49270b9a0d580cf4f31f9a1b6c93f87
author_id_fullname_str_mv	b49270b9a0d580cf4f31f9a1b6c93f87_***_Amira Guirguis
author	Amira Guirguis
author2	Fabrizio Schifano Stefania Chiappini John M. Corkery Norbert Scherbaum Amira Guirguis
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publisher	Elsevier BV
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department_str	Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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description	The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g., synthetic cannabimimetics; synthetic opioids; novel stimulants; novel psychedelics; PCP/ketamine-like compounds; prescribed medicinal compounds; and popular psychotropic herbs/plants) discussed by Internet-based, new/novel psychoactive substances (NPS) enthusiasts, ‘e-psychonauts’.Currently ongoing related in silico studies, followed by further in vitro and in vivo/preclinical studies, will hopefully provide important findings in terms of which molecules within each given NPS class may present with higher levels of receptor affinities, and hence clinical potency. Understanding the pharmacological characteristics/potency of those novel recreational molecules will hopefully help in predicting related NPS diffusion, morbidity, and possible lethality data.
published_date	2021-04-01T04:11:10Z
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The e-psychonaut drugs’ psychopharmacology

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