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In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon...

Wee Kiat Tan, Alyssa Rui Yi Tan, Punitha Sivanandam, Ernest Jing Hui Goh, Ze Ping Yap, Nur Fazilah Saburulla, Karl Austin-Muttitt, Jonathan Mullins Orcid Logo, Aik Jiang Lau

Journal of Pharmacology and Experimental Therapeutics, Volume: 374, Issue: 2, Pages: 295 - 307

Swansea University Authors: Karl Austin-Muttitt, Jonathan Mullins Orcid Logo

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Published in: Journal of Pharmacology and Experimental Therapeutics
ISSN: 0022-3565 1521-0103
Published: American Society for Pharmacology & Experimental Therapeutics (ASPET) 2020
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa55640
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first_indexed 2020-12-29T16:47:12Z
last_indexed 2020-12-30T04:18:42Z
id cronfa55640
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spelling 2020-12-29T16:47:32.5914983 v2 55640 2020-11-10 In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate fafc0917b48af4eaec154646854867f8 Karl Austin-Muttitt Karl Austin-Muttitt true false 4cf2dddedbe1dacb506ec925fdbd5b40 0000-0003-0144-2962 Jonathan Mullins Jonathan Mullins true false 2020-11-10 FGMHL Journal Article Journal of Pharmacology and Experimental Therapeutics 374 2 295 307 American Society for Pharmacology & Experimental Therapeutics (ASPET) 0022-3565 1521-0103 1 8 2020 2020-08-01 10.1124/jpet.120.265249 COLLEGE NANME Medicine, Health and Life Science - Faculty COLLEGE CODE FGMHL Swansea University 2020-12-29T16:47:32.5914983 2020-11-10T13:23:41.1831301 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Wee Kiat Tan 1 Alyssa Rui Yi Tan 2 Punitha Sivanandam 3 Ernest Jing Hui Goh 4 Ze Ping Yap 5 Nur Fazilah Saburulla 6 Karl Austin-Muttitt 7 Jonathan Mullins 0000-0003-0144-2962 8 Aik Jiang Lau 9
title In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
spellingShingle In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
Karl Austin-Muttitt
Jonathan Mullins
title_short In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
title_full In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
title_fullStr In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
title_full_unstemmed In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
title_sort In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
author_id_str_mv fafc0917b48af4eaec154646854867f8
4cf2dddedbe1dacb506ec925fdbd5b40
author_id_fullname_str_mv fafc0917b48af4eaec154646854867f8_***_Karl Austin-Muttitt
4cf2dddedbe1dacb506ec925fdbd5b40_***_Jonathan Mullins
author Karl Austin-Muttitt
Jonathan Mullins
author2 Wee Kiat Tan
Alyssa Rui Yi Tan
Punitha Sivanandam
Ernest Jing Hui Goh
Ze Ping Yap
Nur Fazilah Saburulla
Karl Austin-Muttitt
Jonathan Mullins
Aik Jiang Lau
format Journal article
container_title Journal of Pharmacology and Experimental Therapeutics
container_volume 374
container_issue 2
container_start_page 295
publishDate 2020
institution Swansea University
issn 0022-3565
1521-0103
doi_str_mv 10.1124/jpet.120.265249
publisher American Society for Pharmacology & Experimental Therapeutics (ASPET)
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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published_date 2020-08-01T04:10:00Z
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