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In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon...
Wee Kiat Tan,
Alyssa Rui Yi Tan,
Punitha Sivanandam,
Ernest Jing Hui Goh,
Ze Ping Yap,
Nur Fazilah Saburulla,
Karl Austin-Muttitt,
Jonathan Mullins 
,
Aik Jiang Lau
,
Aik Jiang Lau
Journal of Pharmacology and Experimental Therapeutics, Volume: 374, Issue: 2, Pages: 295 - 307
Swansea University Authors:
Karl Austin-Muttitt, Jonathan Mullins
Full text not available from this repository: check for access using links below.
DOI (Published version): 10.1124/jpet.120.265249
Abstract
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate
| Published in: | Journal of Pharmacology and Experimental Therapeutics |
|---|---|
| ISSN: | 0022-3565 1521-0103 |
| Published: |
American Society for Pharmacology & Experimental Therapeutics (ASPET)
2020
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa55640 |
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2020-12-29T16:47:12Z |
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2020-12-30T04:18:42Z |
| id |
cronfa55640 |
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| fullrecord |
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| spelling |
2020-12-29T16:47:32.5914983 v2 55640 2020-11-10 In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate fafc0917b48af4eaec154646854867f8 Karl Austin-Muttitt Karl Austin-Muttitt true false 4cf2dddedbe1dacb506ec925fdbd5b40 0000-0003-0144-2962 Jonathan Mullins Jonathan Mullins true false 2020-11-10 FGMHL Journal Article Journal of Pharmacology and Experimental Therapeutics 374 2 295 307 American Society for Pharmacology & Experimental Therapeutics (ASPET) 0022-3565 1521-0103 1 8 2020 2020-08-01 10.1124/jpet.120.265249 COLLEGE NANME Medicine, Health and Life Science - Faculty COLLEGE CODE FGMHL Swansea University 2020-12-29T16:47:32.5914983 2020-11-10T13:23:41.1831301 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Wee Kiat Tan 1 Alyssa Rui Yi Tan 2 Punitha Sivanandam 3 Ernest Jing Hui Goh 4 Ze Ping Yap 5 Nur Fazilah Saburulla 6 Karl Austin-Muttitt 7 Jonathan Mullins 0000-0003-0144-2962 8 Aik Jiang Lau 9 |
| title |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| spellingShingle |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate Karl Austin-Muttitt Jonathan Mullins |
| title_short |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| title_full |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| title_fullStr |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| title_full_unstemmed |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| title_sort |
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate |
| author_id_str_mv |
fafc0917b48af4eaec154646854867f8 4cf2dddedbe1dacb506ec925fdbd5b40 |
| author_id_fullname_str_mv |
fafc0917b48af4eaec154646854867f8_***_Karl Austin-Muttitt 4cf2dddedbe1dacb506ec925fdbd5b40_***_Jonathan Mullins |
| author |
Karl Austin-Muttitt Jonathan Mullins |
| author2 |
Wee Kiat Tan Alyssa Rui Yi Tan Punitha Sivanandam Ernest Jing Hui Goh Ze Ping Yap Nur Fazilah Saburulla Karl Austin-Muttitt Jonathan Mullins Aik Jiang Lau |
| format |
Journal article |
| container_title |
Journal of Pharmacology and Experimental Therapeutics |
| container_volume |
374 |
| container_issue |
2 |
| container_start_page |
295 |
| publishDate |
2020 |
| institution |
Swansea University |
| issn |
0022-3565 1521-0103 |
| doi_str_mv |
10.1124/jpet.120.265249 |
| publisher |
American Society for Pharmacology & Experimental Therapeutics (ASPET) |
| college_str |
Faculty of Medicine, Health and Life Sciences |
| hierarchytype |
|
| hierarchy_top_id |
facultyofmedicinehealthandlifesciences |
| hierarchy_top_title |
Faculty of Medicine, Health and Life Sciences |
| hierarchy_parent_id |
facultyofmedicinehealthandlifesciences |
| hierarchy_parent_title |
Faculty of Medicine, Health and Life Sciences |
| department_str |
Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine |
| document_store_str |
0 |
| active_str |
0 |
| published_date |
2020-08-01T04:10:00Z |
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1763753696571686912 |
| score |
11.013731 |