Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors

Hugtenburg, Richard; H., Dimitri D.

doi:10.1088/1742-6596/1662/1/012013

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Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors

Richard Hugtenburg

, Dimitri D. H. Reynard

Journal of Physics: Conference Series, Volume: 1662, Start page: 012013

Swansea University Author: Richard Hugtenburg

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DOI (Published version): 10.1088/1742-6596/1662/1/012013

Abstract

X-ray microbeams are a potential, novel mode of radiation therapy and dosimetry methods are under development that require micrometric spatial precision. The microDiamond detector has the requisite resolution and is composed of diamond which is closely tissue-equivalent. The high density of diamond...

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Published in:	Journal of Physics: Conference Series
ISSN:	1742-6588 1742-6596
Published:	IOP Publishing 2020
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa55578

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spelling	2025-03-20T15:44:36.3498957 v2 55578 2020-11-02 Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors efd2f52ea19cb047e01a01e6fa6fa54c 0000-0003-0352-9607 Richard Hugtenburg Richard Hugtenburg true false 2020-11-02 MEDS X-ray microbeams are a potential, novel mode of radiation therapy and dosimetry methods are under development that require micrometric spatial precision. The microDiamond detector has the requisite resolution and is composed of diamond which is closely tissue-equivalent. The high density of diamond however perturbs of secondary electrons and Monte Carlo methods are needed to determine corrections to accurately measure clinical parameters. The PENELOPE Monte Carlo code has been used to calculate corrections for the output factor (OF) and peak-to-valley dose ratio (PVDR). A high-performance computing (HPC) system was found to be necessary and the calculation took 72 hours when performed on a cluster of 100 CPUs. The correction for the output factor was found to be 1.009±0.016 (2 s.d.). The correction factor for the peak-to-valley ratio was found to be 1.144±0.013 (2 s.d.) and was larger due to Compton scattering of the microbeam in the extracameral components of the detector, in particular the 300 micron bulk diamond crystal. It was found that considerable improvements in efficiency could be achieved without loss of precision by switching off electron transport for electrons that are generated far from the sensitive element of the detector. Journal Article Journal of Physics: Conference Series 1662 012013 IOP Publishing 1742-6588 1742-6596 30 10 2020 2020-10-30 10.1088/1742-6596/1662/1/012013 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University SU Library paid the OA fee (TA Institutional Deal) Swansea University 2025-03-20T15:44:36.3498957 2020-11-02T12:32:10.9196504 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medical Physics Richard Hugtenburg 0000-0003-0352-9607 1 Dimitri D. H. Reynard 2 55578__18791__e22f387b1e414803827df2c3a75e71db.pdf 55578.pdf 2020-12-02T14:14:38.8572080 Output 590908 application/pdf Version of Record true Content from this work may be used under the terms of theCreative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. true eng https://creativecommons.org/licenses/by/3.0/
title	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
spellingShingle	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors Richard Hugtenburg
title_short	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
title_full	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
title_fullStr	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
title_full_unstemmed	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
title_sort	Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors
author_id_str_mv	efd2f52ea19cb047e01a01e6fa6fa54c
author_id_fullname_str_mv	efd2f52ea19cb047e01a01e6fa6fa54c_***_Richard Hugtenburg
author	Richard Hugtenburg
author2	Richard Hugtenburg Dimitri D. H. Reynard
format	Journal article
container_title	Journal of Physics: Conference Series
container_volume	1662
container_start_page	012013
publishDate	2020
institution	Swansea University
issn	1742-6588 1742-6596
doi_str_mv	10.1088/1742-6596/1662/1/012013
publisher	IOP Publishing
college_str	Faculty of Medicine, Health and Life Sciences
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hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
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hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Medical Physics{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medical Physics
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description	X-ray microbeams are a potential, novel mode of radiation therapy and dosimetry methods are under development that require micrometric spatial precision. The microDiamond detector has the requisite resolution and is composed of diamond which is closely tissue-equivalent. The high density of diamond however perturbs of secondary electrons and Monte Carlo methods are needed to determine corrections to accurately measure clinical parameters. The PENELOPE Monte Carlo code has been used to calculate corrections for the output factor (OF) and peak-to-valley dose ratio (PVDR). A high-performance computing (HPC) system was found to be necessary and the calculation took 72 hours when performed on a cluster of 100 CPUs. The correction for the output factor was found to be 1.009±0.016 (2 s.d.). The correction factor for the peak-to-valley ratio was found to be 1.144±0.013 (2 s.d.) and was larger due to Compton scattering of the microbeam in the extracameral components of the detector, in particular the 300 micron bulk diamond crystal. It was found that considerable improvements in efficiency could be achieved without loss of precision by switching off electron transport for electrons that are generated far from the sensitive element of the detector.
published_date	2020-10-30T05:00:30Z
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Monte Carlo based corrections for the dosimetry of x-ray microbeams with diamond detectors

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