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Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography

Marta Peña Fernández, Alexander P. Kao, Frank Witte, Hari Arora Orcid Logo, Gianluca Tozzi

Journal of Biomechanics, Volume: 113, Start page: 110105

Swansea University Author: Hari Arora Orcid Logo

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DOI (Published version): 10.1016/j.jbiomech.2020.110105

Abstract

As a composite material, the mechanical properties of bone are highly dependent on its hierarchical organisation, thus, macroscopic mechanical properties are dictated by local phenomena, such as microdamage resulting from repetitive cyclic loading of daily activities. Such microdamage is associated...

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Published in: Journal of Biomechanics
ISSN: 0021-9290
Published: Elsevier BV 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa55512
first_indexed 2020-10-26T09:12:57Z
last_indexed 2020-12-09T04:10:20Z
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spelling 2020-12-08T13:50:34.8364314 v2 55512 2020-10-26 Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography ed7371c768e9746008a6807f9f7a1555 0000-0002-9790-0907 Hari Arora Hari Arora true false 2020-10-26 EAAS As a composite material, the mechanical properties of bone are highly dependent on its hierarchical organisation, thus, macroscopic mechanical properties are dictated by local phenomena, such as microdamage resulting from repetitive cyclic loading of daily activities. Such microdamage is associated with plastic deformation and appears as a gradual accumulation of residual strains. The aim of this study is to investigate local residual strains in cortical bone tissue following compressive cyclic loading, using in situ X-ray computed tomography (XCT) and digital volume correlation (DVC) to provide a deeper insight on the three-dimensional (3D) relationship between residual strain accumulation, cortical bone microstructure and failure patterns. Through a progressive in situ XCT loading–unloading scheme, localisation of local residual strains was observed in highly compressed regions. In addition, a multi-scale in situ XCT cyclic test highlighted the differences on residual strain distribution at the microscale and tissue level, where high strains were observed in regions with the thinnest vascular canals and predicted the failure location following overloading. Finally, through a continuous in situ XCT compression test of cycled specimens, the full-field strain evolution and failure pattern indicated the reduced ability of bone to plastically deform after damage accumulation due to high number of cyclic loads. Altogether, the novel experimental methods employed in this study, combining high-resolution in situ XCT mechanics and DVC, showed a great potential to investigate 3D full-field residual strain development under repetitive loading and its complex interaction with bone microstructure, microdamage and fracture. Journal Article Journal of Biomechanics 113 110105 Elsevier BV 0021-9290 Cortical bone, In situ mechanics, Cyclic loading, X-ray computed tomography, Digital volume correlation, Residual strains 2 12 2020 2020-12-02 10.1016/j.jbiomech.2020.110105 COLLEGE NANME Engineering and Applied Sciences School COLLEGE CODE EAAS Swansea University 2020-12-08T13:50:34.8364314 2020-10-26T09:00:37.6505097 Faculty of Science and Engineering School of Engineering and Applied Sciences - Biomedical Engineering Marta Peña Fernández 1 Alexander P. Kao 2 Frank Witte 3 Hari Arora 0000-0002-9790-0907 4 Gianluca Tozzi 5 55512__18721__c186585c7f2c4995b9d31402d3f97a61.pdf 55512 (2).pdf 2020-11-23T11:48:42.2979588 Output 3507799 application/pdf Version of Record true ©2020 The Author(s). This is an open access article under the CC BY license true eng http://creativecommons.org/licenses/by/4.0/
title Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
spellingShingle Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
Hari Arora
title_short Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
title_full Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
title_fullStr Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
title_full_unstemmed Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
title_sort Low-cycle full-field residual strains in cortical bone and their influence on tissue fracture evaluated via in situ stepwise and continuous X-ray computed tomography
author_id_str_mv ed7371c768e9746008a6807f9f7a1555
author_id_fullname_str_mv ed7371c768e9746008a6807f9f7a1555_***_Hari Arora
author Hari Arora
author2 Marta Peña Fernández
Alexander P. Kao
Frank Witte
Hari Arora
Gianluca Tozzi
format Journal article
container_title Journal of Biomechanics
container_volume 113
container_start_page 110105
publishDate 2020
institution Swansea University
issn 0021-9290
doi_str_mv 10.1016/j.jbiomech.2020.110105
publisher Elsevier BV
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Biomedical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Biomedical Engineering
document_store_str 1
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description As a composite material, the mechanical properties of bone are highly dependent on its hierarchical organisation, thus, macroscopic mechanical properties are dictated by local phenomena, such as microdamage resulting from repetitive cyclic loading of daily activities. Such microdamage is associated with plastic deformation and appears as a gradual accumulation of residual strains. The aim of this study is to investigate local residual strains in cortical bone tissue following compressive cyclic loading, using in situ X-ray computed tomography (XCT) and digital volume correlation (DVC) to provide a deeper insight on the three-dimensional (3D) relationship between residual strain accumulation, cortical bone microstructure and failure patterns. Through a progressive in situ XCT loading–unloading scheme, localisation of local residual strains was observed in highly compressed regions. In addition, a multi-scale in situ XCT cyclic test highlighted the differences on residual strain distribution at the microscale and tissue level, where high strains were observed in regions with the thinnest vascular canals and predicted the failure location following overloading. Finally, through a continuous in situ XCT compression test of cycled specimens, the full-field strain evolution and failure pattern indicated the reduced ability of bone to plastically deform after damage accumulation due to high number of cyclic loads. Altogether, the novel experimental methods employed in this study, combining high-resolution in situ XCT mechanics and DVC, showed a great potential to investigate 3D full-field residual strain development under repetitive loading and its complex interaction with bone microstructure, microdamage and fracture.
published_date 2020-12-02T07:54:21Z
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