Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Cacciari, Barbara; Balzarini, Jan; Liekens, Sandra; Hamel, Ernest; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Zurlo, Matteo; Finotti, Alessia; Gambari, Roberto

doi:10.3390/molecules25071690

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Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Barbara Cacciari, Jan Balzarini, Sandra Liekens, Ernest Hamel, Andrea Brancale, Salvatore Ferla

, Stefano Manfredini, Matteo Zurlo, Alessia Finotti, Roberto Gambari

Molecules, Volume: 25, Issue: 7, Start page: 1690

Swansea University Author: Salvatore Ferla

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DOI (Published version): 10.3390/molecules25071690

Published in:	Molecules
ISSN:	1420-3049
Published:	MDPI AG 2020
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URI:	https://cronfa.swan.ac.uk/Record/cronfa55228
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first_indexed	2020-10-20T06:23:53Z
last_indexed	2020-11-11T04:09:59Z
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spelling	2020-11-10T11:11:56.1457457 v2 55228 2020-09-20 Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold d4c62248f510e3b221916989a7bbe6a6 0000-0002-5918-9237 Salvatore Ferla Salvatore Ferla true false 2020-09-20 PHAR Journal Article Molecules 25 7 1690 MDPI AG 1420-3049 microtubules; structure–activity relationship; antiproliferative activity; tubulin; tetrahydrothieno[2,3-c]pyridine 7 4 2020 2020-04-07 10.3390/molecules25071690 COLLEGE NANME Pharmacy COLLEGE CODE PHAR Swansea University 2020-11-10T11:11:56.1457457 2020-09-20T14:13:44.2159722 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Romeo Romagnoli 1 Filippo Prencipe 2 Paola Oliva 3 Barbara Cacciari 4 Jan Balzarini 5 Sandra Liekens 6 Ernest Hamel 7 Andrea Brancale 8 Salvatore Ferla 0000-0002-5918-9237 9 Stefano Manfredini 10 Matteo Zurlo 11 Alessia Finotti 12 Roberto Gambari 13 55228__18627__96e2f6adc4004400a5cd12fabdfb469a.pdf 55228.pdf 2020-11-10T11:10:18.5940693 Output 4038369 application/pdf Version of Record true © 2020 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 (CC BY) License true eng http://creativecommons.org/licenses/by/4.0/
title	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
spellingShingle	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold Salvatore Ferla
title_short	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
title_full	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
title_fullStr	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
title_full_unstemmed	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
title_sort	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
author_id_str_mv	d4c62248f510e3b221916989a7bbe6a6
author_id_fullname_str_mv	d4c62248f510e3b221916989a7bbe6a6_***_Salvatore Ferla
author	Salvatore Ferla
author2	Romeo Romagnoli Filippo Prencipe Paola Oliva Barbara Cacciari Jan Balzarini Sandra Liekens Ernest Hamel Andrea Brancale Salvatore Ferla Stefano Manfredini Matteo Zurlo Alessia Finotti Roberto Gambari
format	Journal article
container_title	Molecules
container_volume	25
container_issue	7
container_start_page	1690
publishDate	2020
institution	Swansea University
issn	1420-3049
doi_str_mv	10.3390/molecules25071690
publisher	MDPI AG
college_str	Faculty of Medicine, Health and Life Sciences
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hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
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hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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published_date	2020-04-07T04:09:18Z
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Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

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