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How biomechanical properties of red blood cells change with temperature

Adesola Ademiloye Orcid Logo

Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019), Volume: 2, Pages: 686 - 689

Swansea University Author: Adesola Ademiloye Orcid Logo

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Abstract

In recent decades, the biomechanical properties of human red blood cells (RBCs) have been greatly explored by numerous researchers for diverse reasons. In normal physiological conditions, RBCs undergoes large deformation when traversing thin microcapillaries, however, upon infection by different blo...

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Published in: Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019)
ISBN: 978-0-9562914-5-5
ISSN: 2227-3085 2227-9385
Published: United Kingdom Zeta Computational Resources Ltd., Cardiff, UK 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa52593
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first_indexed 2019-10-28T19:46:17Z
last_indexed 2023-01-11T14:29:47Z
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spelling 2022-10-31T16:43:35.4988350 v2 52593 2019-10-28 How biomechanical properties of red blood cells change with temperature e37960ed89a7e3eaeba2201762626594 0000-0002-9741-6488 Adesola Ademiloye Adesola Ademiloye true false 2019-10-28 MEDE In recent decades, the biomechanical properties of human red blood cells (RBCs) have been greatly explored by numerous researchers for diverse reasons. In normal physiological conditions, RBCs undergoes large deformation when traversing thin microcapillaries, however, upon infection by different blood-related diseases such as malaria, they experience impaired deformability. This paper examines how biomechanical properties of RBCs change with temperature using a multiscale meshfree method. The multiscale meshfree method offers improved accuracy and better computational efficiency as it incorporates RBC membrane microstructural configuration into its constitutive formulation, thereby providing better insights into the changes on the atomistic level. Book chapter Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019) 2 686 689 Zeta Computational Resources Ltd., Cardiff, UK United Kingdom 978-0-9562914-5-5 2227-3085 2227-9385 10 6 2019 2019-06-10 https://www.compbiomed.net/getfile.php?type=14/site_documents&amp;id=CMBE19proceedings-vol2.pdf COLLEGE NANME Biomedical Engineering COLLEGE CODE MEDE Swansea University 2022-10-31T16:43:35.4988350 2019-10-28T13:01:23.7330719 Faculty of Science and Engineering School of Engineering and Applied Sciences - Biomedical Engineering Adesola Ademiloye 0000-0002-9741-6488 1 52593__15738__a428a027380b4c95b6ab0b6cbce36242.pdf CPaper7__2019__Ademiloye 2019 CMBE_Article_Final.pdf 2019-10-28T16:36:08.4354171 Output 513087 application/pdf Accepted Manuscript true false
title How biomechanical properties of red blood cells change with temperature
spellingShingle How biomechanical properties of red blood cells change with temperature
Adesola Ademiloye
title_short How biomechanical properties of red blood cells change with temperature
title_full How biomechanical properties of red blood cells change with temperature
title_fullStr How biomechanical properties of red blood cells change with temperature
title_full_unstemmed How biomechanical properties of red blood cells change with temperature
title_sort How biomechanical properties of red blood cells change with temperature
author_id_str_mv e37960ed89a7e3eaeba2201762626594
author_id_fullname_str_mv e37960ed89a7e3eaeba2201762626594_***_Adesola Ademiloye
author Adesola Ademiloye
author2 Adesola Ademiloye
format Book chapter
container_title Proceedings of the 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2019)
container_volume 2
container_start_page 686
publishDate 2019
institution Swansea University
isbn 978-0-9562914-5-5
issn 2227-3085
2227-9385
publisher Zeta Computational Resources Ltd., Cardiff, UK
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Biomedical Engineering{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Biomedical Engineering
url https://www.compbiomed.net/getfile.php?type=14/site_documents&amp;id=CMBE19proceedings-vol2.pdf
document_store_str 1
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description In recent decades, the biomechanical properties of human red blood cells (RBCs) have been greatly explored by numerous researchers for diverse reasons. In normal physiological conditions, RBCs undergoes large deformation when traversing thin microcapillaries, however, upon infection by different blood-related diseases such as malaria, they experience impaired deformability. This paper examines how biomechanical properties of RBCs change with temperature using a multiscale meshfree method. The multiscale meshfree method offers improved accuracy and better computational efficiency as it incorporates RBC membrane microstructural configuration into its constitutive formulation, thereby providing better insights into the changes on the atomistic level.
published_date 2019-06-10T04:05:02Z
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score 11.037056

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