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Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study

B. L. Carter, R. E. Stiff, K. Elwin, H. A. Hutchings, B. W. Mason, A. P. Davies, R. M. Chalmers, Hayley Hutchings Orcid Logo, Angharad Davies Orcid Logo

European Journal of Clinical Microbiology & Infectious Diseases

Swansea University Authors: Hayley Hutchings Orcid Logo, Angharad Davies Orcid Logo

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DOI (Published version): 10.1007/s10096-019-03603-1

Abstract

A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent a...

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Published in: European Journal of Clinical Microbiology & Infectious Diseases
ISSN: 0934-9723 1435-4373
Published: 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa50656
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first_indexed 2019-06-05T20:55:20Z
last_indexed 2019-09-17T20:14:58Z
id cronfa50656
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spelling 2019-09-17T15:02:25.3392697 v2 50656 2019-06-05 Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study bdf5d5f154d339dd92bb25884b7c3652 0000-0003-4155-1741 Hayley Hutchings Hayley Hutchings true false 62586459693e05b2e1063967e76883f1 0000-0003-4190-8894 Angharad Davies Angharad Davies true false 2019-06-05 HDAT A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent abdominal pain and diarrhea, joint pain and/or fatigue. The number reporting symptoms after C. hominis infection was statistically significantly greater compared with C. parvum. Post-infectious gastrointestinal dysfunction were common after cryptosporidiosis and around 10% of people merited a formal diagnosis of IBS following cryptosporidiosis. Journal Article European Journal of Clinical Microbiology & Infectious Diseases 0934-9723 1435-4373 cryptosporidiosis, sequelae, Cryptosporidium hominis, Cryptosporidium parvum, irritable bowel syndrome 31 12 2019 2019-12-31 10.1007/s10096-019-03603-1 COLLEGE NANME Health Data Science COLLEGE CODE HDAT Swansea University 2019-09-17T15:02:25.3392697 2019-06-05T15:31:39.3401281 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine B. L. Carter 1 R. E. Stiff 2 K. Elwin 3 H. A. Hutchings 4 B. W. Mason 5 A. P. Davies 6 R. M. Chalmers 7 Hayley Hutchings 0000-0003-4155-1741 8 Angharad Davies 0000-0003-4190-8894 9 0050656-18062019150428.pdf 50656.pdf 2019-06-18T15:04:28.4970000 Output 222898 application/pdf Accepted Manuscript true 2020-07-14T00:00:00.0000000 true eng
title Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
spellingShingle Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
Hayley Hutchings
Angharad Davies
title_short Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
title_full Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
title_fullStr Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
title_full_unstemmed Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
title_sort Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study
author_id_str_mv bdf5d5f154d339dd92bb25884b7c3652
62586459693e05b2e1063967e76883f1
author_id_fullname_str_mv bdf5d5f154d339dd92bb25884b7c3652_***_Hayley Hutchings
62586459693e05b2e1063967e76883f1_***_Angharad Davies
author Hayley Hutchings
Angharad Davies
author2 B. L. Carter
R. E. Stiff
K. Elwin
H. A. Hutchings
B. W. Mason
A. P. Davies
R. M. Chalmers
Hayley Hutchings
Angharad Davies
format Journal article
container_title European Journal of Clinical Microbiology & Infectious Diseases
publishDate 2019
institution Swansea University
issn 0934-9723
1435-4373
doi_str_mv 10.1007/s10096-019-03603-1
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 1
active_str 0
description A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent abdominal pain and diarrhea, joint pain and/or fatigue. The number reporting symptoms after C. hominis infection was statistically significantly greater compared with C. parvum. Post-infectious gastrointestinal dysfunction were common after cryptosporidiosis and around 10% of people merited a formal diagnosis of IBS following cryptosporidiosis.
published_date 2019-12-31T04:02:11Z
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